Results 41 to 50 of about 6,578 (240)

Molecular analysis of PKU-associated PAH mutations: a fast and simple genotyping test [PDF]

, 2018
: Neonatal screening for phenylketonuria (PKU, OMIM: 261600) was introduced at the end of the 1960s. We developed a rapid and simple molecular test for the most frequent phenylalanine hydroxylase (PAH, Gene ID: 5053) mutations.
Antonio Angeloni, ARTIOLA, CRISTIANA, CARDUCCI, Carla, CARDUCCI, Claudia, D'AMICI, SIRIO, GIOVANNIELLO, TERESA, Manuela Tolve, PASQUALI, Amelia, PIZZUTI, Antonio, Vincenzo Leuzzi   +9 more
core   +1 more source

Tetrahydro‐6‐biopterin is associated with tetrahydro‐7‐biopterin in primary murine mast cells [PDF]

FEBS Letters, 1992
Murine bone marrow‐derived mast cells proliferate in response to interleukin 3. In addition to 6‐biopterin, 7‐biopterin was identified in these cells by HPLC analysis of iodine oxidized extracts and by alkaline permanganate oxidation to the 6‐ and 7‐carboxylic acids. 7‐Biopterin comprised 31.9 (± 7.7)% of the total biopterin.
Ziegler, Irmgard, Hültner, Lothar
openaire   +2 more sources

Effect of 7,8 -Dihydroneopterin, Biopterin and Isoxanthopterin on Cholesterol and Phospholipid Content and Phospholipid Biosynthesis in Vitro

Pteridines, 1996
Incorporation of fatty acids into phospholipids has been investigated using samples of rat liver tissue homogenate (Krebs-Ringer-phosphate buffer, pH=7.4, containing 0.3% albumin, fatty acid mixture and glycerol). The addition of 7,8-dihydroneopterin and
Rudzite Vera, Jurika Edite, Baier-Bitterlich Gabriele, Wachterl Helmut, Fuchs Dietmar   +4 more
doaj   +1 more source

Measurement of Neopterin and Biopterin in Urine from Phenylketonuria Heterozygotes and Normal Controls

Pteridines, 1991
The effect of an oral load of phenylalanine (100 mg/kg body weight) on the levels of neopterin and biopterin in urine has been determined in 8 heterozygotes for classical phenylketonuria and 25 supposed normal controls. In basal conditions, neopterin and
Ruiz-Vázquez P., Bel Y., Garcia A. M., Cabello M. L., Dalmau J., Alós T., Catalá J. L., Ferré J.   +7 more
doaj   +1 more source

Studies on the regulation of endothelial nitric oxide synthase in endothelial dysfunction [PDF]

, 2016
Ischaemic heart disease and cerebrovascular disease are the leading causes of morbidity and mortality in the world. The underlying progression of the disease is linked to a reduction in the bioavailability of nitric oxide. One factor contributing to this
Cerrato, Ruha
core   +1 more source

Chemical structure of 1-O-(L-erythro-biopterin-2'-yl)-a-glucose isolated from a cyanobacterium Synechococcus sp. PCC 7942

Pteridines, 2001
A pteridine glycoside in Synechococcus sp. PCC 7942, the structure of which had been tentatively identified as biopterin-glucoside, was isolated and characterized for its exact chemical structure by 2D-NMR spectroscopy. The determined structure is 1-0-(L-
Choi Yong Kee, Hwang Yoon Kyung, Kang Yong Han, Park Young Shik   +3 more
doaj   +1 more source

Comparative Study of Blood Neopterin and Biopterins in Patients with COVID-19 and Secondary Bacterial Infection. [PDF]

J Clin Med
Eguchi T, Niiyama S, Kamikokuryo C, Madokoro Y, Shimono K, Hara S, Ichinose H, Kakihana Y.   +7 more
europepmc   +3 more sources

The Levels of Neopterin, Biopterin and the Neopterin/Biopterin Ratio in Urine from Control Subjects and Patients with Alzheimer's Disease and Down's Syndrome

Pteridines, 1995
The levels of neopterin, biopterin and the neopterin/biopterin ratio (NIB) were measured in urine samples taken from normal young and elderly control subjects, exceptionally healthy elderly control subjects classified according to the 'Senieur' protocol ...
Armstrong R.A., Cattell R .J., Winsper S.J., Blair J.A.   +3 more
doaj   +1 more source

Neopterin and Cytokines in Hereditary Dystonia and Parkinson's Disease

Pteridines, 1999
Both neopterin and biopterin concentrations in cerebrospinal fluid from patients with Parkinson's disease, in which the nigrostriatal dopamine neurons degenerate, were lower than those from age-matched older control subjects.
Nagatsu T., Ichinose H., Mogi M., Togari A.   +3 more
doaj   +1 more source

Biopterin in Parkinson's disease. [PDF]

Journal of Neurology, Neurosurgery & Psychiatry, 1987
Tetrahydrobiopterin is an essential co-factor in the natural synthesis of dopamine. Oral tetrahydrobiopterin was given in small doses to four patients with early Parkinson's disease but had no discernible effect.
A P, Moore, P O, Behan, W, Jacobson, W L, Armarego   +3 more
openaire   +2 more sources