Results 41 to 50 of about 8,158 (274)

Plasma Levels of Neopterin and Biopterin in the Umbilical Vessels and the Maternal Vein

Pteridines, 2003
Tetrahydrobiopterin (BH4) is a highly bioactive pterin required for nitric oxide synthase and monooxygenases of aromatic amino acids, and is involved in the synthesis of nitric oxide, catecholamines and Serotonin.
Iwanaga Naoko, Yamamasu Seiichi, Tachibana Daisuke, Nishio Junko, Nakai Yuichiro, Shintaku Haruo, Imanaka Motoharu, Yamano Tsunekazu, Ishiko Osamu   +8 more
doaj   +1 more source

Usefulness of serum biopterin as a predictive biomarker for childhood asthma control: A prospective cohort study

Allergology International, 2019
Background: Pteridines are metabolites of tetrahydrobiopterin, which serves as co-enzyme of nitric oxide synthase. We sought to investigate the usefulness of pteridines as biomarkers for childhood asthma control.
Saki Kasuga, Daijiro Kabata, Tomoko Sakaguchi, Satoshi Kudoh, Satsuki Nishigaki, Yusuke Higa, Shiori Fujikawa, Hiroko Fujitani, Ayumi Shintani, Takashi Hamazaki, Haruo Shintaku   +10 more
doaj   +1 more source

Studies on the regulation of endothelial nitric oxide synthase in endothelial dysfunction [PDF]

, 2016
Ischaemic heart disease and cerebrovascular disease are the leading causes of morbidity and mortality in the world. The underlying progression of the disease is linked to a reduction in the bioavailability of nitric oxide. One factor contributing to this
Cerrato, Ruha
core   +1 more source

Tetrahydro‐6‐biopterin is associated with tetrahydro‐7‐biopterin in primary murine mast cells [PDF]

FEBS Letters, 1992
Murine bone marrow‐derived mast cells proliferate in response to interleukin 3. In addition to 6‐biopterin, 7‐biopterin was identified in these cells by HPLC analysis of iodine oxidized extracts and by alkaline permanganate oxidation to the 6‐ and 7‐carboxylic acids. 7‐Biopterin comprised 31.9 (± 7.7)% of the total biopterin.
Ziegler, Irmgard, Hültner, Lothar
openaire   +2 more sources

Endothelial, Sympathetic, and Cardiac Function in Inherited (6 R )- l -Erythro-5,6,7,8-Tetrahydro- l -Biopterin Deficiency [PDF]

Circulation: Cardiovascular Genetics, 2010
Lila Mayahi, Lydia Mason, Katherine Bleasdale-Barr, Ann E. Donald, Iris Trender‐Gerhard, Mary G. Sweeney, Mary B. Davis, Nicholas Wood, Christopher J. Mathias, Laura Watson, Denis Pellerin, Simon Heales, John Deanfield, Kailash P. Bhatia, Judith Murray‐Rust, Aroon D. Hingorani   +15 more
openalex   +2 more sources

Measurement of Neopterin and Biopterin in Urine from Phenylketonuria Heterozygotes and Normal Controls

Pteridines, 1991
The effect of an oral load of phenylalanine (100 mg/kg body weight) on the levels of neopterin and biopterin in urine has been determined in 8 heterozygotes for classical phenylketonuria and 25 supposed normal controls. In basal conditions, neopterin and
Ruiz-Vázquez P., Bel Y., Garcia A. M., Cabello M. L., Dalmau J., Alós T., Catalá J. L., Ferré J.   +7 more
doaj   +1 more source

Tetrahydrobiopterin Supplementation: Elevation of Tissue Biopterin Levels Accompanied by a Relative Increase in Dihydrobiopterin in the Blood and the Role of Probenecid-Sensitive Uptake in Scavenging Dihydrobiopterin in the Liver and Kidney of Rats

PLoS ONE, 2016
Tetrahydrobiopterin (BH4) is an essential cofactor of nitric oxide synthase (NOS) and aromatic amino acid hydroxylases. BH4 and 7,8-dihydrobiopterin (BH2) are metabolically interchangeable at the expense of NADPH.
Akiko Ohashi, Yusuke Saeki, Tomonori Harada, M. Naito, Tomihisa Takahashi, S. Aizawa, H. Hasegawa   +6 more
semanticscholar   +1 more source

Chemical structure of 1-O-(L-erythro-biopterin-2'-yl)-a-glucose isolated from a cyanobacterium Synechococcus sp. PCC 7942

Pteridines, 2001
A pteridine glycoside in Synechococcus sp. PCC 7942, the structure of which had been tentatively identified as biopterin-glucoside, was isolated and characterized for its exact chemical structure by 2D-NMR spectroscopy. The determined structure is 1-0-(L-
Choi Yong Kee, Hwang Yoon Kyung, Kang Yong Han, Park Young Shik   +3 more
doaj   +1 more source

Organic anion transporters, OAT1 and OAT3, are crucial biopterin transporters involved in bodily distribution of tetrahydrobiopterin and exclusion of its excess

Molecular and Cellular Biochemistry, 2017
Tetrahydrobiopterin (BH4) is a common coenzyme of phenylalanine-, tyrosine-, and tryptophan hydroxylases, alkylglycerol monooxygenase, and NO synthases (NOS).
Akiko Ohashi, K. Mamada, Tomonori Harada, M. Naito, Tomihisa Takahashi, S. Aizawa, H. Hasegawa   +6 more
semanticscholar   +1 more source

Dysregulated Choline, Methionine, and Aromatic Amino Acid Metabolism in Patients with Wilson Disease: Exploratory Metabolomic Profiling and Implications for Hepatic and Neurologic Phenotypes. [PDF]

, 2019
Wilson disease (WD) is a genetic copper overload condition characterized by hepatic and neuropsychiatric symptoms with a not well-understood pathogenesis.
Czlonkowska, Anna, Kim, Kyoungmi, Litwin, Tomasz, Mazi, Tagreed A, Medici, Valentina, Sarode, Gaurav V, Shibata, Noreene M   +6 more
core   +2 more sources