Results 141 to 150 of about 120,525 (339)
Design challenges for space bioreactors [PDF]
The design of bioreactors for operation under conditions of microgravity presents problems and challenges. Absence of a significant body force such as gravity can have profound consequences for interfacial phenomena. Marangoni convection can no longer be
Petersen, G. R., Seshan, P. K.
core +1 more source
Advanced Intelligent Systems, EarlyView.Liquid metal “sloshing” by the robot's own actuator is proposed to improve the self‐healing performance. The proposed method drastically enhances the healed strength by decomposing the surface oxides and the impurities. The method contributes to the world's first demonstration of active self‐healing behavior performed by a life‐sized legged robot. Self‐
Shinsuke Nakashima +8 more
wiley +1 more source
Selective Phosphorylation of Phenols and Benzenediols by the Kinase PsiK and Variants Thereof
Angewandte Chemie, EarlyView.PsiK from Psilocybe cubensis phosphorylates a diverse set of substituted phenols and benzenediols beyond its native substrate. High‐throughput screening of active site mutant libraries using DESI‐MS enabled protein engineering of PsiK, further expanding its substrate scope.
Ahram Kim +8 more
wiley +2 more sources
Animal Models and Experimental Medicine, EarlyView.This represents the first serial hepatocyte transplantation pig model designed to investigate the massive hepatocyte proliferation in vivo. Leveraging this novel model, we achieved serial hepatocyte transplantation and regeneration in a porcine model, where the transplanted hepatocytes effectively repopulated the livers of two‐generation model pigs in ...
Zhiqiang Han +10 more
wiley +1 more source
Marine DrugsThe enormous potential attributed to prodigiosin regarding its applicability as a natural pigment and pharmaceutical agent justifies the development of sound bioprocesses for its production.
Ricardo F. S. Pereira +1 more
doaj +1 more source
Journal of Advanced Manufacturing and Processing, EarlyView.ABSTRACT The use of perfusion bioreactor systems is increasing in biomanufacturing due to their potential for productivity gains, increased facility utilization, and process intensification. Systematic studies on cell retention devices are limited even if these devices are often described as process‐limiting during perfusion.
Delphine Tavernier +2 more
wiley +1 more source
Design Principles for Laser-Printed Macrofluidics
InventionsThis paper presents a novel method for fabricating fluidic circuits using laser printing technology. The method allows for rapid prototyping of macrofluidic devices with control over fluid manipulation and environmental conditions.
Gilad Gome +3 more
doaj +1 more source
Advanced NanoBiomed Research, EarlyView.A novel extracellular matrix (ECM)‐integrated mesenchymal stem cell spheroid bioprinting technology has been introduced to significantly enhance exosome production for therapeutic applications. By optimizing spheroid size and ECM composition, the study demonstrates an 18.4‐fold increase in exosome yield compared to 2D culture systems.
Jun‐Ho Heo +3 more
wiley +1 more source
Advanced NanoBiomed Research, EarlyView.Traditional static culture provides limited physiological relevance for evaluation of vascular grafts. A perfusion bioreactor system can provide more accurate in vitro model for evaluation of vascular grafts, exposing endothelial cells on 3D structure to physiological or pathological shear stress.
Praveesuda L. Michael +10 more
wiley +1 more source