Results 11 to 20 of about 3,674,475 (302)
Minimum Information about a Biosynthetic Gene cluster [PDF]
Nature Chemical Biology, 2015 A wide variety of enzymatic pathways that produce specialized metabolites in bacteria, fungi and plants are known to be encoded in biosynthetic gene clusters.Tilmann Weber, Düsterhus, Stephanie, Brady, Sean, Zotchev, Sergey B., Haines, A., Haines, A. S., Seipke, R. F., Willey, J.M., Carla S Jones, Lee, C. Y., Neha Garg, Bode, H., Andreas Bechthold, Leonilde M Moreira, De Bruijn, I.,, Pernodet, Jean Luc, Caffrey, P., Aigle, B., Jan Claesen, Monroe, E.A., Sherman, David H, Fewer, D. P.,, Fergal O'Gara, Fischbach, Michael A., Yu, F., Kim, H., Payne, Shelley M., Gust, B.,, Bruijn, Irene, De, Bertolt Gust, Breitling, R., Balskus, Emily P., Linquan, Bai, Metsä-Ketelä, Mikko, Osburne, M. S., De Mot, Rene, Zhang, Changsheng, Kegler, C.,, Ploux, O., Lautru, S., Harald Gross, Entian, Karl-Dieter, Van Der Donk, W. A.,, Jones, C. S., Wyckoff, Elizabeth, Dorrestein, Pieter C, Driessen, Arnold JM, Rosconi, Federico, Hillwig, Matthew L, Yvonne Mast, Borriss, Rainer, Keller, Nancy P., Douglas A Mitchell, Borriss, R.,, Kuzuyama, T.,, Mast, Yi, Dorrestein, P.C., Viaud, M.,, van Wezel, Gilles P, Yan, Xiaohui, Edwards, Daniel J, Breitling, R.,, Katz, L., Tobias, Nicholas J., Driessen, Arnold J M, Pan, G., Zotchev, S. B., Kwon, H. J.,, Helfrich, E.J.N., Donadio, S.,, Pati, A., Yim, G., Doyle, Sean, Viaud, Muriel,, Michael J Smanski, Carsten Kegler, Eric J N Helfrich, R Cameron Coates, Tahlan, K., Jensen, S. E., Tian, Zhenhua, Michalis Hadjithomas, Fewer, D., Höfte, M.,, Petras, D.,, Walsh, Christopher T, Moreira, L. M., Cheng, Yi-Qiang, Schmitt, E.K., Karl-Dieter Entian, Rob Lavigne, Smanski, M. J., Mueller, Rolf, Irene de Bruijn, Fischbach, M., Gerwick, W. H.,, van der Donk, Wilfred A, Willey, Joanne M, Biggins, John B, Kaysser, L.,, Ben Shen, Chooi, Y. H., Seipke, Ryan F., Neilan, Brett A., Seipke, R.F., Payne, Shelley M, Miroslav Petricek, Melnik, Alexey V., Chia Y Lee, Barona-Gómez, F.,, Scott, Barry, Petras, Daniel, Süssmuth, Roderich D., Kötter, P.,, Sergey B Zotchev, Axel A Brakhage, Wilkinson, Barrie, Gilles P van Wezel, Gerwick, William H, Dorrestein, P. C.,, Monica Höfte, Brakhage, Axel A, Yan, X.,, Gerwick, Lena, Edwards, Daniel J., Driessen, A. J. M., Chooi, Y., Klassen, J.L., Moore, M.,, Takano, E.,, Wiemann, Philipp, Micklefield, J., Adam C Jones, Yit Heng Chooi, Andriy Luzhetskyy, Donadio, S., Balskus, Emily P, Zhenhua Tian, Ju, J., Osbourn, A., Walsh, C. T.,, Glöckner, F. O., Renzo Kottmann, Tobias, N.J., Wyckoff, E., Helfrich, Eric J N, Cox, R.J., Garg, N.,, Jones, A. C., Donk, Wilfred A., Van Der, Wezel, Gilles P., Van, Cruz-Morales, Pablo, Hillwig, M. L.,, Kyrpides, Nikos C, Mantovani, S.M., Süssmuth, R.D., Shen, B., Brady, S., Jungmann, Katrin, Duesterhus, Stephanie, Pablo Cruz-Morales, Moss, N., Liu, W.,, Scott, B.,, Brady, S. F.,, Tsunematsu, Yuta, Nikos C Kyrpides, Salas, J. A.,, Eriko Takano, Kottmann, R., Zhe Rui, Luzhetskyy, A., Krug, D.,, Biggins, J. B., Srikanth Duddela, Walsh, C.T., Donia, M., Cox, R., Sosio, Margherita, Neilan, B. A.,, Kegler, Carsten, Grace Yim, Donia, M.S., Garg, N., Petricek, M., Frank Oliver Glöckner, Süssmuth, R. D., Micklefield, J.,, Reen, F. J.,, Ehling-Schulz, M., De Mot, R.,, Petricek, M.,, Carl J Balibar, Federico Rosconi, Hyung-Jin Kwon, Walton, Jonathan D., Bode, Helge B., Mantovan, Simone M., Biggins, J., Claesen, J.,, Nuetzmann, Hans-Wilhelm, Jones, Carla S., Mantovani, Simone M., Balibar, C.J., Gross, H.,, Chooi, Yi, Takano, Eriko; id_orcid, Yim, Grace, Brady, S.F., Doyle, S.,, Medema, M. H., Balibar, Carl J., Shelley M Payne, Jean-Luc Pernodet, Mahmud, T., Osburne, M. S.,, Balibar, C. J., Kai Blin, Medema, M.H., Donk, Wilfred A van der, Walton, J.D., Wright, Gerard D., Keller, N. P., Haines, Anthony S, Esther K Schmitt, Dorrestein, Pieter C., Helfrich, Eric J.N., Moore, Marcus, K\uf6tter, P., Kai, Blin, Jörn Piel, William H Gerwick, Van Wezel, G. P.,, Donadio, Stefano, Stefano Donadio, Edwards, D. J.,, Thomas, C.M., Nielsen, J., Haines, Anthony S., Walsh, Christopher T., Bode, Helge B, Yilmaz, Pelin, Kaysser, L., Méndez, C., Guohui Pan, Matthew L Hillwig, Medema, M. H.,, Biggins, John B., Tian, Z.,, Claesen, J., Jensen, Susan E., Ryan F Seipke, Monroe, Emily A., Bode, H.B., Rosconi, F.,, Gust, B., Ehling-Schulz, M.,, Melnik, A., Takano, Eriko, Bechthold, A., Cummings, M.,, Nützmann, H-W., Haines, A. S.,, Payne, S. M.,, Wohlleben, Wolfgang, Simone M Mantovani, Juan Pablo Gomez-Escribano, Leonard Kaysser, David P Fewer, Nathan Moss, Truman, A. W., Evi Stegmann, Ehling-Schulz, Monika, Donia, M. S., Cheng, Yi Qiang, Kim, H.U., Fischbach, M.A., Brakhage, A. A.,, F Jerry Reen, Moore, B. S.,, Balibar, Carl J, Liu, Wen, Hillwig, M. L., Nützmann, H. W.,, Jones, Jon, Hertweck, C.,, Ishida, Keishi, Neilan, Brett A, Roderich D Süssmuth, Moore, Bradley S, David H Sherman, Monroe, E. A., Nielsen, Jens, Mot, René De, Yi Tang, Daniel Petras, Walton, J. D., Shen, B.,, Smanski, M. J.,, Nicholas J Tobias, Gomez-Escribano, J., Fischbach, Michael A, Duddela, S.,, Wright, G.D., Schmitt, Esther K, Yilmaz, P.,, Yu, F.,, Jonathan D Walton, Ju, Katrin, Mitchell, D. A.,, Nadine Ziemert, Oscar P Kuipers, Jones, A., Russell J Cox, Gl\uf6ckner, F. O., de Bruijn, Irene, Lee, C.Y., Kuipers, O.P., Gross, Harald, Gerwick, L., Zotchev, S. B.,, Kottmann, Renzo, Hideaki Oikawa, Düsterhus, S.,, Mast, Y.,, Salas, José A., Caffrey, Patrick, D\ufcsterhus, S., Truman, Andrew W, Bruijn, Irene de, Jones, Adam C., Yu, Fengan, Nielsen, Jens B,, Tang, Yi, Nielsen, Jens B., Rui, Zhe, Wezel, G.P. van, Katz, L.,, Rolf Müller, Hyun Uk Kim, Jones, C., Hertweck, Christian, Geiger, C.,, Petras, D., Mahmud, Taifo, Pernodet, J-L., Wright, G. D., O'Gara, F.,, Düsterhus, S., Moss, N.,, Entian, K. D.,, Tang, Y.,, M\ufcller, R., Entian, K.D., Smanski, M.J., Donia, Mohamed S, Moss, Nathan, Lavigne, R., Kuzuyama, Tomohisa, Pernodet, J. L., Salas, J. A., Ishida, K.,, Ostash, B.,, Stegmann, E., Jones, C.S., Hillwig, M., Gust, Bertolt, Apel, Alexander K, Kim, H. U.,, Hadjithomas, M., Greule, A.,, Thomas, Christopher M., Gerwick, William H., Klassen, J. L., Gomez-Escribano, J. P.,, Lavigne, R.,, Jonathan L Klassen, Osbourn, A.,, Lavigne, Rob, Jensen, Jens, Tobias, N., Donia, M. S.,, Jos M Raaijmakers, Wezel, Gilles P van, Breitling, Rainer, Glöckner, F. O.,, Walsh, C. T., Carmen Méndez, Brett A Neilan, Yuta Tsunematsu, Changsheng Zhang, Schmitt, Esther, Nützmann, Hans Wilhelm, Jason Micklefield, Amrita Pati, Neilan, B.A., Metsä-Ketelä, M., Yu, Yuta, Barona-Gómez, Francisco, Driessen, Arnold J.M., Ziemert, N.,, Thomas, Christopher M, Biggins, J.B., Mantovani, S. M.,, Kuipers, Oscar P., Jungmann, K.,, Barona-G\uf3mez, F., Hans-Wilhelm Nützmann, Luzhetskyy, Andriy, Tian, Z., Bechthold, A.,, Kwon, H.J., Pernodet, Jean-Luc, Koetter, Peter, Tang, Y., Marnix H Medema, Rui, Z.,, Stephanie Düsterhus, Geiger, Christoph, Mitchell, D.A., O’Gara, Fergal, Christopher T Walsh, Osburne, Marcia S, Wright, Gerard D, Aigle, Bertrand, Moore, Jon, M\ue9ndez, C., Raaijmakers, J. M., Zhang, C.,, Hillwig, M.L., Andrew W Truman, Brakhage, Axel A., Barona-Gómez, F., Luzhetskyy, Andriy N, Helfrich, E.J., Brakhage, A.A., Pieter C Dorrestein, Raaijmakers, J.M., Cheng, Y. Q., Lautru, S.,, Nützmann, H., Mast, Yvonne, Pan, G.,, Yi-Qiang Cheng, Jianhua Ju, Xie, Y.,, Nielsen, Jens B, Wilkinson, B.,, Anthony S Haines, Kötter, Peter, Kuipers, O. P., Christoph Geiger, Medema, M., Smanski, Michael J, Linquan, B., Weber, Tilmann, Brady, Sean F, Krug, D., Höfte, Monica, Joanne M Willey, Jensen, S.E., Mantovani, Simone M, Süssmuth, Roderich D, Wolfgang Wohlleben, Jones, Adam C, Ju, Jianhua, Kwon, Hyung Jin, Micklefield, Jason, Kegler, C., Moore, B. S., Gerard D Wright, Jens Nielsen, Krug, Daniel, Moreira, L.M., Ploux, O.,, Cheng, Y., Sherman, D.H., De Bruijn, I., Apel, A. K.,, Kuipers, O. P.,, Fewer, D. P., Viaud, M., Moreira, Leonilde M., Osbourn, Anne, Balskus, E. P., Entian, K., Kyrpides, Nikos C., Entian, K-D., Medema, Marnix H, Melnik, A. V., Ostash, Bohdan, Driessen, A. J. M.,, Apel, A.K., Nützmann, H. W., Weber, T., Tahlan, K.,, Wilkinson, B., Müller, Rolf, Glöckner, F.O., Yunchang Xie, Wilfred A van der Donk, Hadjithomas, M.,, Truman, Andrew W., Cheng, Yo, Kuipers, Oscar P; id_orcid, Van Der Donk, W., Anne Osbourn, Biggins, J. B.,, Tsunematsu, Y.,, Nett, M., Kyrpides, N.C., O Gara, Fergal, Moore, B.S., Bode, H. B., Weber, T.,, Donia, Mohamed S., Moore, M., Thomas, Christopher; id_orcid, Bohdan Ostash, Driessen, Arnold J. M., Pati, A.,, Müller, R.,, Cheng, Yi, Méndez, C.,, Emily P Balskus, Cox, R. J., Masschelein, J.,, Brakhage, A., Yim, G.,, Ploux, Olivier, Tobias, N. J., Cox, Russell, Xiaohui Yan, Kyrpides, N. C.,, Fischbach, M. A., Kwon, H. J., Cummings, M., Nancy P Keller, Wohlleben, W.,, Yan, X., Reen, F. Jerry, Keller, Nancy P, Barrie Wilkinson, Rosconi, F., Mikko Metsä-Ketelä, Yim, Yi, Fewer, David P, Wen Liu, Christian Hertweck, Jensen, S. E.,, Helfrich, E. J. N., Piel, J., Tahlan, Kapil, Sherman, D. H., Sivonen, Kaarina, Stegmann, Evi, Cruz-Morales, P., Apel, A. K., Edwards, D. J., O'Gara, F., Wiemann, P.,, Sherman, David H., Dorrestein, P., Cox, Russell J, Entian, Karl Dieter, Mitchell, Douglas A., Scott, B., Kwon, Hyung-Jin, Willey, J. M.,, Driessen, A., Reen, F Jerry, Petricek, Miroslav, Dorrestein, P. C., Marcus Moore, Gomez-Escribano, J. P., Mitchell, D. A., Sean Doyle, Kormanec, J.,, Sivonen, K.,, René De Mot, Glöckner, Frank Oliver, Bertrand Aigle, Zotchev, S.B., Bode, Helge Björn, Christopher M Thomas, Wiemann, P., Francisco Barona-Gómez, Rainer Borriss, Walton, Jonathan D, Duddela, Srikanth, S\ufcssmuth, R. D., Salas Fernández, José Antonio, Driessen, A.J., Schmitt, Esther K., Rui, Z., Alexander K Apel, Duddela, S., Coates, R Cameron, H\uf6fte, M., Kaarina Sivonen, Mitchell, Douglas A, Kyrpides, N. C., Anja Greule, Yilmaz, Yi, Liu, X.,, Müller, R., Hertweck, C., Ju, Juan Pablo, Bai Linquan, Doyle, S., Balskus, E.P., Raaijmakers, Jos M, Sosio, M., Luzhetskyy, A.,, Nützmann, Hans-Wilhelm, Nett, M.,, Helfrich, E., Pan, Guohui, Seipke, Ryan F, Susan E Jensen, Driessen, A.J.M., Xie, Yunchang, Marcia S Osburne, Greule, A., Piel, Jörn, Shen, Ben, Schmitt, E. K., Kapil Tahlan, Willey, Joanne M., Apel, A., Aigle, B.,, Pati, Amrita, Hillwig, Matthew L., Gerwick, W., Bechthold, Andreas, Gloeckner, Frank Oliver, Mantovani, S., Melnik, A. V.,, Jon Clardy, Truman, A.W., Seipke, R. F.,, Keller, N. P.,, Liu, Xinyu, Gerwick, W. H., José A Salas, Lautru, Sylvie, Schmitt, E. K.,, Arnold J M Driessen, Melnik, Alexey V, Mot, René, De, Edwards, Daniel, Gomez-Escribano, Juan Pablo, Masschelein, J., Oikawa, H.,, Keller, N.P., Monroe, E. A.,, Helfrich, Eric JN, Joleen Masschelein, Moore, Bradley S., Reen, F., Melnik, A.V., Stegmann, E.,, Borriss, R., Linquan, B.,, Lee, Chia Y, Reen, F.J., Sherman, D. H.,, Osburne, Marcia S., Monroe, E., Daniel Krug, Smanski, Michael J., Caffrey, P.,, Kormanec, J., Salas, Jose A, Cruz-Morales, P.,, Kötter, P., Masschelein, Joleen, Jensen, Susan E, Piel, Joern, van Wezel, G.P., Oikawa, H., Rainer Breitling, Cheng, Y. Q.,, Tobias, N. J.,, Medema, Marnix H., Gerwick, W.H., Coates, R.C., Jungmann, K., Méndez Fernández, María del Carmen, Geiger, C., Margherita Sosio, Moreira, L. M.,, Van Der Donk, W. A., Ishida, K., Neilan, B. A., Kuipers, Oscar P, Brady, Sean F., Sylvie Lautru, Kottmann, R.,, Coates, R. C., Peter Kötter, Cox, R. J.,, Lee, C. Y.,, Keishi Ishida, Balskus, E. P.,, Chooi, Yit Heng, Kim, Hyun Uk, Mets\ue4-Ketel\ue4, M., Höfte, M., Zhang, C., Balibar, C., Nützmann, H.W., Willey, J. M., Lee, Chia Y., Pernodet, J. L.,, Apel, Alexander K., Pelin Yilmaz, Gross, H., Brady, S. F., Katrin Jungmann, O\u27Gara, F., van der Donk, W.A., Wyckoff, E.,, John B Biggins, Thomas, Christopher M.; id_orcid, Ju, Guohui, Jones, A. C.,, Coates, R. C.,, Emily A Monroe, Cox, Russell J., Markus Nett, Balibar, C. J.,, Sivonen, K., Blin, K.,, Takano, E., Coates, R. Cameron, Ziemert, Nadine, Fengan Yu, Coates, R., Reen, F. J., Clardy, J., Jones, A.C., Haines, A.S., Walton, J. D.,, Leonard Katz, Edwards, D., Bode, H. B.,, Monika Ehling-Schulz, Fewer, D.P., Osburne, M.S., Klassen, Jonathan L., Viaud, Muriel, Yilmaz, P., Kormanec, Jan, Entian, K. D., Katz, Leonard, Pernodet, J.L., Cummings, Matthew, Monroe, Emily A, Van Wezel, G. P., Tomohisa Kuzuyama, Daniel J Edwards, Suessmuth, Roderich D, Xie, Y., Schmitt, J.K., Barry Scott, Edwards, D.J., Gomez-Escribano, J.P., Süssmuth, R. D.,, Blin, K., Kuzuyama, T., Greule, Anja, Tsunematsu, Y., Nett, Markus, Klassen, J. L.,, Piel, J.,, Raaijmakers, Jos M., Helfrich, E. J. N.,, Blin, Kai, Jones, Carla S, Mast, Y., Payne, S.M., Mantovani, S. M., Fewer, David P., Bradley S Moore, Clardy, Jon, Claesen, Jan, Wright, G. D.,, Thomas, C. M.,, Truman, A. W.,, Sean F Brady, Jan Kormanec, Patrick Caffrey, Muriel Viaud, Raaijmakers, J. M.,, Thomas, C. M., Helfrich, Eric J. N., Alexey V Melnik, Salas, J.A., Payne, S. M., Clardy, J.,, Zotchev, Sergey B, Tang, Yihan, Ostash, B., Lena Gerwick, Gerwick, L.,, Brakhage, A. A., Chooi, Y.H., Ju, J.,, Liu, W., Méndez, Carmen, Matthew Cummings, Mahmud, T.,, Kwon, H-J., Elizabeth Wyckoff, Michael A Fischbach, Garg, Neha, van der Donk, Wilfred A., N\ufctzmann, H. W., Chooi, Y. H.,, Liu, X., Cheng, Y-Q., Metsä-Ketelä, M.,, De Mot, R., Jones, C. S.,, Mohamed S Donia, Kim, H. U., Ziemert, N., Kaysser, Leonard, Moreira, Leonilde M, Oikawa, Hideaki, Fischbach, M. A.,, Wohlleben, W., van Wezel, Gilles P., Helge B Bode, Sosio, M.,, Olivier Ploux, Ju, Xiaohui, Taifo Mahmud, Tobias, Nicholas J, Klassen, Jonathan L, Xinyu Liu, Philipp Wiemann, Hadjithomas, Michalis, Balskus, E., O'Gara, Fergal, Schmitt, E., Kwon HJ, Raaijmakers, J., Cummings M, Greule A, Petras D, Hertweck C, Claesen J, Lee CY, Yu F, Moreira, L., Biggins JB, Seipke, R., Tahlan K, Bechthold A, Tobias NJ, Borriss R, Höfte M, Kaysser L, Walton JD, Lavigne R, Neilan BA, Sherman DH, Ploux O, Süssmuth RD, Kuzuyama T, Shen B, Balskus EP, Suessmuth, R., Tsunematsu Y, Monroe EA, de Bruijn I, de Brujin, Irene, Yim G, Gerwick WH, Chooi, Yit H., Takano E, Jungmann K, Duddela S, Mahmud T, Salas, J., Rui Z, Thomas, C., Ishida K, Walton, J., Micklefield J, Blin K, Wright, G., Cox RJ, Kwon, H., Osbourn A, Dorrestein PC, Kyrpides NC, Yan X, O'Gara F, Wiemann P, Mantovani SM, Katz L, Edwards DJ, Méndez C, Krug D, Kegler C, Keller, N., Osburne, M., Nützmann HW, Wilkinson B, Jones AC, van Wezel, G., Mitchell DA, Fischbach MA, Scott B, Bode HB, Nielsen J, Barona-Gómez F, Moss N, Reen FJ, Lee, C., Lautru S, Walsh CT, Zhang C, Hadjithomas M, Kyrpides, N., Sosio M, van Wezel GP, Smanski MJ, Jones CS, Moreira LM, Koetter, P., Zotchev, S., Xie Y, Thomas CM, Garg N, Donadio S, Wyckoff E, Brady SF, Petricek M, Nett M, Jensen, S., Zotchev SB, Coates RC, Ziemert N, Apel AK, Luzhetskyy A, Osburne MS, Breitling R, Gloeckner, F., Nuetzmann, H., Jensen SE, Oikawa H, Yilmaz P, Truman AW, Tian Z, Pernodet JL, Raaijmakers JM, Kottmann R, Payne, S., Stegmann E, Liu W, Liu X, Klassen, J., Haines AS, Linquan B, Mueller, R., Pati A, Doyle S, Moore BS, Cruz-Morales P, Duesterhus, S., Kormanec J, Ostash B, Truman, A., Kötter P, Mitchell, D., Geiger C, Neilan, B., Smanski, M., Kuipers, O., Breitling, Rainer; id_orcid, Moore, B., Melnik AV, Wohlleben W, Gomez-Escribano, Juan P., Pernodet, J., Driessen AJ, Entian KD, Chooi YH, Müller R, Kim HU, Pan G, Clardy J, Salas JA, Kuipers OP, Viaud M, Rosconi F +999 morecore +22 more sourcesFunctional Analysis of the Fusarielin Biosynthetic Gene Cluster [PDF]
Molecules, 2016 Fusarielins are polyketides with a decalin core produced by various species of Aspergillus and Fusarium. Although the responsible gene cluster has been identified, the biosynthetic pathway remains to be elucidated.Aida Droce, Wagma Saei, Simon Hartung Jørgensen, Reinhard Wimmer, Henriette Giese, Rasmus Dam Wollenberg, Teis Esben Sondergaard, Jens Laurids Sørensen +7 moredoaj +4 more sourcesCharacterization of the Actinonin Biosynthetic Gene Cluster
ChemBioChem, 2018 Wolf F, Leipoldt F, Kulik A, Wibberg D, Kalinowski J, Kaysser L. Characterization of the Actinonin Biosynthetic Gene Cluster. CHEMBIOCHEM. 2018;19(11):1189-1195.The hydroxamate moiety of the natural product actinonin mediates inhibition of ...Kaysser, Leonard, Kulik, Andreas, Wibberg, Daniel, Leipoldt, Franziska, Felix Wolf, Andreas Kulik, Leonard Kaysser, Wolf, Felix, Franziska Leipoldt, Daniel Wibberg, Kalinowski, Jörn, Jörn Kalinowski +11 morecore +3 more sourcesBiosynthetic Gene Cluster of Linaridin Peptides Contains Epimerase Gene [PDF]
ChemBioChem, 2022 Salinipeptins belong to the type-A linaridin class of ribosomally synthesized and post-translationally modified peptides (RiPPs) comprising 22 amino acid residues with multiple D-amino acids.Ogasawara, Yasushi, Yasuharu Satoh, Satoh, Yasuharu, Dairi, Tohru, Tohru Dairi, Xiao, Wanlu, Yasushi Ogasawara, Wanlu Xiao +7 morecore +4 more sourcesIdentification, heterologous expression, and characterization of the tolypodiol biosynthetic gene cluster through an integrated approach. [PDF]
, 2023 Cyanobacteria are tremendous producers of biologically active natural products including the potent anti-inflammatory compound tolypodiol. However, linking biosynthetic gene clusters with compound production in cyanobacteria has lagged behind other ...Philip , Williams, Timothy J., O\u27Donnell, Kyle , Axt, Benjamin, Philmus, Daniel, Back, Juan , Vanegas, Joshua , Gurr +6 morecore +2 more sourcesThe Biosynthetic Gene Clusters of Aminocoumarin Antibiotics [PDF]
Planta Medica, 2006 Plants and microorganisms are the most important sources of secondary metabolites in nature. For research in the functional genomics of secondary metabolism, and for the biotechnological application of such research by genetic engineering and combinatorial biosynthesis, most microorganisms offer a unique advantage to the researcher: the biosynthetic ...Shu-Ming, Li, Lutz, Heideopenaire +2 more sourcesMultiplexed mobilization and expression of biosynthetic gene clusters
Nature Communications, 2022 AbstractBacterial genomes contain large reservoirs of biosynthetic gene clusters (BGCs) that are predicted to encode unexplored natural products. Heterologous expression of previously unstudied BGCs should facilitate the discovery of additional therapeutically relevant bioactive molecules from bacterial culture collections, but the large-scale ...Vincent Libis, Logan W. MacIntyre, Rabia Mehmood, Liliana Guerrero, Melinda A. Ternei, Niv Antonovsky, Ján Burian, Zongqiang Wang, Sean F. Brady +8 moreopenaire +3 more sources
