Results 41 to 50 of about 3,674,475 (302)
Minimum Information about a Biosynthetic Gene cluster [PDF]
, 2017 A wide variety of enzymatic pathways that produce specialized metabolites in bacteria, fungi and plants are known to be encoded in biosynthetic gene clusters.Geiger, Christoph, Yim, Grace, Düsterhus, Stephanie, Payne, Shelley M, Ploux, Olivier, Viaud, Muriel, Scott, Barry, Petras, Daniel, Kormanec, Jan, Osburne, Marcia S, Liu, Xinyu, Wright, Gerard D, de Bruijn, Irene, Aigle, Bertrand, Lautru, Sylvie, Katz, Leonard, Melnik, Alexey V, Cummings, Matthew, Monroe, Emily A, Gomez-Escribano, Juan Pablo, Haines, Anthony S, Gross, Harald, Wilkinson, Barrie, Gerwick, William H, Keller, Nancy P, Kottmann, Renzo, Brakhage, Axel A, Fewer, David P, Gerwick, Lena, Moore, Marcus, Caffrey, Patrick, Lee, Chia Y, Truman, Andrew W, Yu, Fengan, Sherman, David, Tahlan, Kapil, Wiemann, Philipp, Sivonen, Kaarina, Stegmann, Evi, Donadio, Stefano, Tang, Yi, Rui, Zhe, Mast, Yvonne, Greule, Anja, Nett, Markus, Kötter, Peter, Bode, Helge B, Hertweck, Christian, Linquan, Bai, Smanski, Michael J, Brady, Sean F, Weber, Tilmann, Yilmaz, Pelin, Blin, Kai, Cox, Russell J, Metsä-Ketelä, Mikko, Jones, Carla S, Mahmud, Taifo, Helfrich, Eric J N, Zhang, Changsheng, Höfte, Monica, Kwon, Hyung-Jin, Masschelein, Joleen, Jensen, Susan E, Cruz-Morales, Pablo, Mantovani, Simone M, Reen, F Jerry, Petricek, Miroslav, Entian, Karl-Dieter, Süssmuth, Roderich D, Clardy, Jon, Jones, Adam C, Claesen, Jan, Kyrpides, Nikos C, Ju, Jianhua, Wyckoff, Elizabeth, Micklefield, Jason, Dorrestein, Pieter C, Takano, Eriko, Hillwig, Matthew L, Rosconi, Federico, Borriss, Rainer, Donia, Mohamed S, Moss, Nathan, Jungmann, Katrin, Kuzuyama, Tomohisa, Wohlleben, Wolfgang, Krug, Daniel, Glöckner, Frank Oliver, Gust, Bertolt, Apel, Alexander K, Zotchev, Sergey B, O, Fergal, van Wezel, Gilles P, Tsunematsu, Yuta, Walton, Jonathan D, Ehling-Schulz, Monika, Kuipers, Oscar P, Edwards, Daniel J, Yan, Xiaohui, Duddela, Srikanth, Driessen, Arnold J M, Méndez, Carmen, Sosio, Margherita, Osbourn, Anne, Chooi, Yit Heng, Kim, Hyun Uk, Salas, José A, Kegler, Carsten, Medema, Marnix H, Ostash, Bohdan, Coates, R Cameron, Lavigne, Rob, Walsh, Christopher, Balibar, Carl J, Doyle, Sean, Mitchell, Douglas A, Liu, Wen, Garg, Neha, Tian, Zhenhua, Müller, Rolf, Breitling, Rainer, Ishida, Keishi, Neilan, Brett A, Moore, Bradley S, Raaijmakers, Jos M, Nützmann, Hans-Wilhelm, Nielsen, Jens, Cheng, Yi-Qiang, Pan, Guohui, De Mot, René, Seipke, Ryan F, Barona-Gómez, Francisco, Kaysser, Leonard, Xie, Yunchang, Moreira, Leonilde M, Thomas, Christopher M, Oikawa, Hideaki, van der Donk, Wilfred A, Piel, Jörn, Willey, Joanne M, Fischbach, Michael A, Shen, Ben, Biggins, John B, Ziemert, Nadine, Luzhetskyy, Andriy, Schmitt, Esther K, Pati, Amrita, Pernodet, Jean-Luc, Tobias, Nicholas J, Klassen, Jonathan L, Balskus, Emily, Hadjithomas, Michalis, Bechthold, Andreas +153 morecore +1 more sourceHeterologous expression of the diazaquinomycin biosynthetic gene cluster [PDF]
Journal of Industrial Microbiology and Biotechnology, 2019 Abstract Members of the diazaquinomycin class of natural products have shown potent and selective activity against Mycobacterium tuberculosis. However, poor aqueous solubility has prevented extensive studies in animal models thus far. Our long-term goal is to harness knowledge regarding diazaquinomycin biosynthesis towards the generation Jana, Braesel, Tuan Anh, Tran, Alessandra S, Eustáquio +2 moreopenaire +2 more sourcesA single Streptomyces symbiont makes multiple antifungals to support the fungus farming ant Acromyrmex octospinosus [PDF]
, 2013 Attine ants are dependent on a cultivated fungus for food and use antibiotics produced by symbiotic Actinobacteria as weedkillers in their fungus gardens. Actinobacterial species belonging to the genera Pseudonocardia, Streptomyces and Amycolatopsis have Brearley, Charles, Seipke, Ryan F., Barke, Joerg, Yu, Douglas W., Goss, Rebecca J. M., Hill, Lionel, Hutchings, Matthew I. +6 morecore +2 more sourcesIdentification and analysis of the resorcinomycin biosynthetic gene cluster [PDF]
Bioscience, Biotechnology, and Biochemistry, 2015 Abstract Resorcinomycin (1) is composed of a nonproteinogenic amino acid, (S)-2-(3,5-dihydroxy-4-isopropylphenyl)-2-guanidinoacetic acid (2), and glycine. A biosynthetic gene cluster was identified in a genome database of Streptoverticillium roseoverticillatum by searching for orthologs of the genes responsible for biosynthesis of ...Koichi, Ooya, Yasushi, Ogasawara, Motoyoshi, Noike, Tohru, Dairi +3 moreopenaire +2 more sourcesMIBiG 4.0: advancing biosynthetic gene cluster curation through global collaboration [PDF]
Specialized or secondary metabolites are small molecules of biological origin, often showing potent biological activities with applications in agriculture, engineering and medicine.Aguilar, C., Donahey, M. S. C., Teufel, R., Medema, M. H., Huynh, T., Jing, J., Katsuyama, Y., Zimmermann, C., Mahmud, T., Jayachandran, S., Streiff, A. B., Hooft, J. J. V. D., Barbieri, H. B., Macias, M. I., Liu, J., Santos-Medellin, C., Linington, R. G., Parra, J., Witte, T. E., Aleti, G., Augustijn, H. E., Barbosa, J. C. J., Koetsier, R. A., Borriss, R., Bulcock, B. W., Ryu, B., Bernaldo-Aguero, J., Creamer, K. E., Ostash, B. O., Tarnowski, M. J., Rubio, M. P., Kim, G. J., Hanif, N., Grayson, N. E., Bozhuyuk, K. A., Hindra, H., Kalkreuter, E., Kim, H., Rutz, A., Kakumu, Y., Li, S., Carrion, V. J., Choi, H., Barra, L., Larsen, N. J., Pham, H. T., Duncan, K. R., Damiani, T., Krug, D., Navarro, J., Robinson, S. L., Bhatt, K. M., Saldanha, M., Rosas-Becerra, L. R., Kollten, C., Gutierrez-Garcia, K., Haslinger, K., Ramesh, S., Singh, G., Connolly, J. A., Rojo, M. Y. A., Otani, H., Cumsille, A., Warnasinghe, R., Williams, S. E., Hoing, L., Korenskaia, A., Licona-Cassani, C., Merrild, A., Le, N., Singh, H., Kubach, N., Cano-Prieto, C., Rey, T., Kust, A., Reher, R., Zimmer, L., Gu, W., Strüder, A., Tan, B., Sowa, S. T., Truman, A. W., Doering, D. T., Chromy, J., Parade, D. S., Rosiles, P. Y., Salvi, L., Borges, R. M., Charria-Giron, E., Kang, K. B., Jenner, M., Sieber, S., Fewer, D. P., Tugizimana, F., Guerra, S., Machushynets, N. V., Torring, T., Yu, J., Paliya, S., Cediel-Becerra, J. D., Shah, A. D., Park, J., Lopez, J. A. V., Libis, V., Müller, A. V., Weber, T., Nguyen, G., Yang, D., Castro-Falcon, G., Dillen, J., Jung, J. J., Schoellhorn, S. M., Szenei, J., Ulbricht, C., Durusu, S., Singh, K. S., Yamada, K., Trindade, M., Frediansyah, A., Bielinski, V. A., Sokolova, N., Niedermeyer, T. H. J., Pan, X., Lorio, M., Flores, S. G., Weddeling, H. G., Hart, L., Surup, F., Cruz, A. A., Selem, N., Lee, B. T., Ossowicki, A., Kushnareva, A. K., Morgan, K. D., Kriukova, Y., Barrett, S. E., Kim, W., Gurevich, A., Rasmussen, M. H., Gavriilidou, A., Beemelmanns, C., Holland, D. C., Chooi, Y. H., Steffen, K., Sala, G. D., Foldi, J., Carter, R. S., Beqaj, D., Klapper, M., Wezel, G. P. V., Zdouc, M. M., Al-Salihi, S. A., Phan, C., Li, Y., Dallery, J., Launay, A. P., Owen, C., Winter, J. M., Schumm, C., Avelar-Rivas, J. A., Kruijff, M. D., Dommaraju, S. R., McBride, C. M., Chagas, F. O., Metsä-Ketela, M., Alharthi, S. A., Mantri, S., Alberti, F., Philmus, B., Hu, J., Helfrich, E. J., Bretscher, K. M., Fetter, A., Pidot, S. J., Gonzalez-Salazar, L. A., Piel, J., Lev, K. L., Bailey, C. B., Reitz, Z. L., Brigham, M. W., Blin, K., Larralde, M., McLellan, R. M., Arishi, A. A., Feuermann, M., Crusemann, M., Romero-Otero, A., Maleckis, M., Lien, A., Hrab, P., Booth, T. J., Jeong, E., Loureiro, C., Hemmann, J. L., Sonnenschein, E. C., Greco, C., Mast, Y., Biermann1, F., Berger, T., Buedenbender, L., Shishido, T. K., Lamber, J., Padva, L., Panghal, M., Damas-Ramos, L. C., Martin, B. D., Terlouw1, B. R., D’Agostino, P. M., Gomez-Escribano, J. P., Gentile, A., Mitchell, D. A., Williams, K., Breitenbach, M., Castelo-Branco, R., Capela, J., Kang, S., Rocca, S. M. W., Faussurier, B., Bader, C. D., Stegmann, E., Segato, L. G. B., Kovacs, A. T., Ortega, L. R. T., Lund, G., Bettenbuhl, S. M., Udwary, D. W., Axt, K. K., Martinez-Martinez, A. M., Hebra, T., Rice, A. J., Baunach, M., Sahadeo, L., Rond, T. D., Gomez, J. E. G., Tagirdzhanov, A., Sbaraini, N., Chaudhry, V., Rego, A., Sánchez-Carvajal, E., Chevrette, M. G., Maximo, M. F., Zhou, Z., Holme, J. E., Ulanova, D., Louwen, N. L., Charlop-Powers, Z., Walmsley, M., Collemare, J., Choi, Y., Gerke, J., Pourmohsenin, B., Ellerhorst, M., Gerstmans, H., Svenningsen, T., Sehnal, L., Horch, T., He, B., Rigolet, A., Kunjapur, A. M., O’Hare, J. H., Weir, A. N., Silviani, V., Choupannejad, R., Melkonian, C., Sosio, M., Tvilum, M., Vader, L., Akiyama, D. Y., Garza, E. A., Zimmermann, A., Avalon, N. E., Tong, Y., Rakhmanov, M., Kim, H. U., Ziemert, N., Lacovelli, R., Thome, N. U., Nguyen, H. T., Lftime, D., Egbert, S., Chaudhri, A. A., Pup, E. D., Lebeer, S., Lee, K., Sweeney, D., Alanjary, M., Hwang, J. +286 morecore +1 more source
