Results 61 to 70 of about 373,234 (333)

Minimum Information about a Biosynthetic Gene cluster [PDF]

, 2017
A wide variety of enzymatic pathways that produce specialized metabolites in bacteria, fungi and plants are known to be encoded in biosynthetic gene clusters.
Geiger, Christoph, Yim, Grace, Düsterhus, Stephanie, Payne, Shelley M, Ploux, Olivier, Viaud, Muriel, Scott, Barry, Petras, Daniel, Kormanec, Jan, Osburne, Marcia S, Liu, Xinyu, Wright, Gerard D, de Bruijn, Irene, Aigle, Bertrand, Lautru, Sylvie, Katz, Leonard, Melnik, Alexey V, Cummings, Matthew, Monroe, Emily A, Gomez-Escribano, Juan Pablo, Haines, Anthony S, Gross, Harald, Wilkinson, Barrie, Gerwick, William H, Keller, Nancy P, Kottmann, Renzo, Brakhage, Axel A, Fewer, David P, Gerwick, Lena, Moore, Marcus, Caffrey, Patrick, Lee, Chia Y, Truman, Andrew W, Yu, Fengan, Sherman, David, Tahlan, Kapil, Wiemann, Philipp, Sivonen, Kaarina, Stegmann, Evi, Donadio, Stefano, Tang, Yi, Rui, Zhe, Mast, Yvonne, Greule, Anja, Nett, Markus, Kötter, Peter, Bode, Helge B, Hertweck, Christian, Linquan, Bai, Smanski, Michael J, Brady, Sean F, Weber, Tilmann, Yilmaz, Pelin, Blin, Kai, Cox, Russell J, Metsä-Ketelä, Mikko, Jones, Carla S, Mahmud, Taifo, Helfrich, Eric J N, Zhang, Changsheng, Höfte, Monica, Kwon, Hyung-Jin, Masschelein, Joleen, Jensen, Susan E, Cruz-Morales, Pablo, Mantovani, Simone M, Reen, F Jerry, Petricek, Miroslav, Entian, Karl-Dieter, Süssmuth, Roderich D, Clardy, Jon, Jones, Adam C, Claesen, Jan, Kyrpides, Nikos C, Ju, Jianhua, Wyckoff, Elizabeth, Micklefield, Jason, Dorrestein, Pieter C, Takano, Eriko, Hillwig, Matthew L, Rosconi, Federico, Borriss, Rainer, Donia, Mohamed S, Moss, Nathan, Jungmann, Katrin, Kuzuyama, Tomohisa, Wohlleben, Wolfgang, Krug, Daniel, Glöckner, Frank Oliver, Gust, Bertolt, Apel, Alexander K, Zotchev, Sergey B, O, Fergal, van Wezel, Gilles P, Tsunematsu, Yuta, Walton, Jonathan D, Ehling-Schulz, Monika, Kuipers, Oscar P, Edwards, Daniel J, Yan, Xiaohui, Duddela, Srikanth, Driessen, Arnold J M, Méndez, Carmen, Sosio, Margherita, Osbourn, Anne, Chooi, Yit Heng, Kim, Hyun Uk, Salas, José A, Kegler, Carsten, Medema, Marnix H, Ostash, Bohdan, Coates, R Cameron, Lavigne, Rob, Walsh, Christopher, Balibar, Carl J, Doyle, Sean, Mitchell, Douglas A, Liu, Wen, Garg, Neha, Tian, Zhenhua, Müller, Rolf, Breitling, Rainer, Ishida, Keishi, Neilan, Brett A, Moore, Bradley S, Raaijmakers, Jos M, Nützmann, Hans-Wilhelm, Nielsen, Jens, Cheng, Yi-Qiang, Pan, Guohui, De Mot, René, Seipke, Ryan F, Barona-Gómez, Francisco, Kaysser, Leonard, Xie, Yunchang, Moreira, Leonilde M, Thomas, Christopher M, Oikawa, Hideaki, van der Donk, Wilfred A, Piel, Jörn, Willey, Joanne M, Fischbach, Michael A, Shen, Ben, Biggins, John B, Ziemert, Nadine, Luzhetskyy, Andriy, Schmitt, Esther K, Pati, Amrita, Pernodet, Jean-Luc, Tobias, Nicholas J, Klassen, Jonathan L, Balskus, Emily, Hadjithomas, Michalis, Bechthold, Andreas   +153 more
core   +1 more source

Figure S2 – NB-183-Biosynthetic gene cluster regions.pdf

, 2023
Biosynthetic gene cluster ...
Lawrence Goodridge (4821957), Noah Bryan (17549065), Melinda Precious (17549093), Opeyemi Lawal (14999119), Yanhong Chen (304926), Mitra Soni (17549067), Valeria R. Parreira (13049283)   +6 more
core   +1 more source

Isolation and characterization of the gibberellin biosynthetic gene cluster in Sphaceloma manihoticola

, 2008
Gibberellins (GAs) are tetracyclic diterpenoid phytohormones that were first identified as secondary metabolites of the fungus Fusarium fujikuroi (teleomorph, Gibberella fujikuroi). GAs were also found in the cassava pathogen Sphaceloma manihoticola, but
Hedden, P., Bomke, C., Gong, F., Bömke, Christiane, Tudzynski, Bettina, Gong, Fan, Tudzynski, B., Rojas, M. C., Hedden, Peter, Rojas, Maria Cecilia   +9 more
core   +1 more source

Biosynthetic Gene Cluster of a d‐Tryptophan‐Containing Lasso Peptide, MS‐271

ChemBioChem, 2018
MS‐271, produced by Streptomyces sp. M‐271, is a lasso peptide natural product comprising 21 amino acid residues with a d‐tryptophan at its C terminus. Because lasso peptides are ribosomal peptides, the biosynthesis of MS‐271, especially the mechanism of
Zhi-Mei Feng, Yasushi Ogasawara, S. Nomura, T. Dairi   +3 more
semanticscholar   +1 more source

Marine Microbial-Derived Resource Exploration: Uncovering the Hidden Potential of Marine Carotenoids

Marine Drugs, 2022
Microbes in marine ecosystems are known to produce secondary metabolites. One of which are carotenoids, which have numerous industrial applications, hence their demand will continue to grow.
Ray Steven, Zalfa Humaira, Yosua Natanael, Fenny M. Dwivany, Joko P. Trinugroho, Ari Dwijayanti, Tati Kristianti, Trina Ekawati Tallei, Talha Bin Emran, Heewon Jeon, Fahad A. Alhumaydhi, Ocky Karna Radjasa, Bonglee Kim   +12 more
doaj   +1 more source

Control of Aflatoxin Production of Aspergillus flavus and Aspergillus parasiticus Using RNA Silencing Technology by Targeting aflD (nor-1) Gene. [PDF]

, 2011
Aspergillus flavus and Aspergillus parasiticus are important pathogens of cotton, corn, peanuts and other oil-seed crops, producing toxins both in the field and during storage.
Daniel Caley, Naresh Magan, Abdel-Hadi, A, Abdel-Hadi, Ahmed, Caley, D. P., Carter, D. R., Ahmed M. Abdel-Hadi, Ahmed Abdel-Hadi, David R. F. Carter, Caley, D, Carter, D, Daniel P. Caley, Magan, Naresh, David Carter, Magan, N   +14 more
core   +1 more source

Identifying the Biosynthetic Gene Cluster for Triacsins with an N-hydroxytriazene Moiety.

bioRxiv, 2018
Triacsins are a family of natural products containing an N-hydroxytriazene moiety not found in any other known secondary metabolites. Though many studies have examined the biological activity of triacsins in lipid metabolism, the biosynthesis of ...
Frederick F. Twigg, W. Cai, Wei Huang, Joyce Liu, Michio Sato, Tynan J. Perez, Jiaxin Geng, Moriel J. Dror, Ismael Montanez, Tate L. Tong, Hyunsu Lee, Wenjun Zhang   +11 more
semanticscholar   +1 more source

Cloning and Characterization of the Ravidomycin and Chrysomycin Biosynthetic Gene Clusters [PDF]

ChemBioChem, 2010
AbstractThe gene clusters responsible for the biosynthesis of two antitumor antibiotics, ravidomycin and chrysomycin, have been cloned from Streptomyces ravidus and Streptomyces albaduncus, respectively. Sequencing of the 33.28 kb DNA region of the cosmid cosRav32 and the 34.65 kb DNA region of cosChry1‐1 and cosChryF2 revealed 36 and 35 open reading ...
Madan K, Kharel, S Eric, Nybo, Micah D, Shepherd, Jürgen, Rohr   +3 more
openaire   +2 more sources

Isolation and structure elucidation of lipopeptide antibiotic taromycin B from the activated taromycin biosynthetic gene cluster

Journal of antibiotics (Tokyo. 1968), 2017
In the ongoing effort to unlock the chemical potential of marine bacteria, genetic engineering of biosynthetic gene clusters (BGCs) is increasingly used to awake or improve expression of biosynthetic genes that may lead to discovery of novel bioactive ...
Kirk A Reynolds, H. Luhavaya, Jie Li, Samira Dahesh, V. Nizet, Kazuya Yamanaka, B. Moore   +6 more
semanticscholar   +1 more source

Biosynthesis of Quinolidomicin, the Largest Known Macrolide of Terrestrial Origin: Identification and Heterologous Expression of a Biosynthetic Gene Cluster over 200 kb.

Organic Letters, 2018
Quinolidomicin A1 is the largest macrolide compound from terrestrial sources, consisting of a 60-membered ring, and its biosynthetic gene cluster was revealed to be over 200 kb. The gene cluster for quinolidomicin was cloned and heterologously expressed.
T. Hashimoto, J. Hashimoto, I. Kozone, Keita Amagai, Teppei Kawahara, Shunji Takahashi, H. Ikeda, K. Shin‐ya   +7 more
semanticscholar   +1 more source