Results 251 to 260 of about 3,454,458 (298)

Identification of the lydiamycin biosynthetic gene cluster in a plant pathogen guides structural revision and identification of molecular target. [PDF]

Proc Natl Acad Sci U S A
Ford JJ, Santos-Aberturas J, Hems ES, Sallmen JW, Bögeholz LAK, Polturak G, Osbourn A, Wright JA, Rodnina MV, Vereecke D, Francis IM, Truman AW.   +11 more
europepmc   +1 more source

Structure Elucidation, Biosynthetic Gene Cluster Distribution, and Biological Activities of Ketomemicin Analogs in <i>Salinispora</i>. [PDF]

Mar Drugs
Castro-Falcón G, Guillén-Matus DG, Silva EBD, Guo W, Ross A, Sá Magalhães Serafim M, Fernandes THM, Tantillo DJ, O'Donoghue AJ, Jensen PR.   +9 more
europepmc   +1 more source

Whole-Genome Sequencing and Biosynthetic Gene Cluster Analysis of Novel Entomopathogenic Bacteria <i>Xenorhabdus thailandensis</i> ALN 7.1 and ALN 11.5. [PDF]

Biology (Basel)
Meesil W, Ardpairin J, Sharkey LKR, Pidot SJ, Vitta A, Thanwisai A.   +5 more
europepmc   +1 more source

Context matters: assessing the impacts of genomic background and ecology on microbial biosynthetic gene cluster evolution. [PDF]

mSystems
Salamzade R, Kalan LR.
europepmc   +1 more source

LsrL modulates Lsr2-induced chromatin structure to tune biosynthetic gene cluster regulation in Streptomyces venezuelae

Ramirez V, Tiller L, Szafran MJ, Zhang X, Jakimowicz D, Elliot M, Freddolino L.   +6 more
europepmc   +1 more source

Sub-functionalization and epigenetic regulation of a biosynthetic gene cluster in Solanaceae

Priego-Cubero S, Knoch E, Wang Z, Alseekh S, Braun K, Chapman P, Fernie A, Liu C, Becker C.   +8 more
europepmc   +1 more source

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A gene cluster of the ochratoxin A biosynthetic genes inPenicillium

Mycotoxin Research, 2006
A putative ochratoxin A (OTA) biosynthetic gene cluster inP. nordicum has been identified. The first part of the gene cluster is located on a DNA fragment of 10 kb in length and harbours three genes. A gene with high homology to an alkaline serine protease gene (accession number AY557343), which represents the upstream border of the cluster ...
R, Geisen, M, Schmidt-Heydt, A, Karolewiez   +2 more
openaire   +2 more sources

Sequence analysis of porothramycin biosynthetic gene cluster [PDF]

Folia Microbiologica, 2014
The biosynthetic gene cluster of porothramycin, a sequence-selective DNA alkylating compound, was identified in the genome of producing strain Streptomyces albus subsp. albus (ATCC 39897) and sequentially characterized. A 39.7 kb long DNA region contains 27 putative genes, 18 of them revealing high similarity with homologous genes from biosynthetic ...
Jiří Janata, Zdenek Kameník, Dana Ulanova   +2 more
exaly   +3 more sources

Biosynthetic gene clusters for epipolythiodioxopiperazines in filamentous fungi

Mycological Research, 2008
Epipolythiodioxopiperazines (ETPs) are toxic secondary metabolites made only by fungi. Recent research efforts have provided insight into the molecular mechanisms of the toxicity of these compounds. The availability of complete genome sequences for many fungi has also facilitated the identification of putative ETP biosynthetic gene clusters. Expression
Ellen M, Fox, Barbara J, Howlett
openaire   +2 more sources

Lessons from the rifamycin biosynthetic gene cluster

Current Opinion in Chemical Biology, 1999
There is currently intense interest in unravelling the modus operandi of type I modular polyketide synthases in order to lay the ground work for their use in the combinatorial biosynthesis of new bioactive molecules. Much of our knowledge is derived from studies on 6-deoxyerythronolide B (DEBS), the enzyme assembling the polyketide backbone of ...
H G, Floss, T W, Yu
openaire   +2 more sources