Results 261 to 270 of about 3,454,458 (298)

Cloning and Sequencing of the Chaetocin Biosynthetic Gene Cluster

ChemBioChem, 2013
How a fungus does it: The epidithiodiketopiperazine (ETP) fungal alkaloids, which include gliotoxin, have garnered much attention since their initial isolation. The cloning and sequencing of the biosynthetic gene cluster for another ETP, chaetocin A were used to suggest a route towards dimerization and sulfur incorporation in these molecules.
Thomas, Gerken, Christopher T, Walsh
openaire   +2 more sources

Biosynthetic Gene Clusters in Bacteria: A Review

Proceedings of the Pakistan Academy of Sciences: B. Life and Environmental Sciences, 2022
Soil is a nutrient-rich environment that harbors billions of microbial species. The diversity of microbes in an environment varies with the change in edaphic factors. To survive these environmental changes, microbes produce secondary metabolites which are not directly associated with their growth and reproduction. Bacterial genomes possess biosynthetic
Rimsha Dilshad, Nazia Jamil, Rida Batool
openaire   +1 more source

A Bioinformatics Workflow for Investigating Fungal Biosynthetic Gene Clusters

2022
Predicting secondary metabolite biosynthetic gene clusters is a routine analysis performed for each newly sequenced fungal genome. Yet, the usefulness of such predictions remains restricted as they provide total numbers of biosynthetic pathways with only very limited biological significance.
Collemare, J., Navarro-Munoz, J.C.
openaire   +3 more sources

Ergot alkaloids: structure diversity, biosynthetic gene clusters and functional proof of biosynthetic genes

Nat. Prod. Rep., 2011
Ergot alkaloids are toxins and important pharmaceuticals which are produced biotechnologically on an industrial scale. They have been identified in two orders of fungi and three families of higher plants. The most important producers are fungi of the genera Claviceps, Penicillium and Aspergillus (all belonging to the Ascomycota).
Christiane, Wallwey, Shu-Ming, Li
openaire   +2 more sources

Characterization of the secondary metabolite biosynthetic gene clusters in archaea

Computational Biology and Chemistry, 2019
Secondary metabolites are a range of bioactive compounds yielded by bacteria, fungi and plants, etc. The published archaea genomic data provide the opportunity for efficient identification of secondary metabolite biosynthetic gene clusters (BGCs) by genome mining. However, the study of secondary metabolites in archaea is still rare.
Shengqin Wang, Zhihong Zheng, Huixi Zou, Nan Li, Mingjiang Wu   +4 more
openaire   +3 more sources

Horizontal transfer and evolution of the biosynthetic gene cluster for benzoxazinoids in plants

Plant Communications, 2022
Michael Timko, Chu-Yu Ye, Dongya Wu
exaly  

The Biosynthetic Gene Cluster for Sestermobaraenes—Discovery of a Geranylfarnesyl Diphosphate Synthase and a Multiproduct Sesterterpene Synthase from Streptomyces mobaraensis

Angewandte Chemie - International Edition, 2020
Jeroen Dickschat
exaly  

Identification of the kinanthraquinone biosynthetic gene cluster by expression of an atypical response regulator

Bioscience, Biotechnology and Biochemistry, 2021
Jun-Pil Jang, Katsuyuki Sakai, Hiroyuki Koshino   +2 more
exaly  

Genetic localization of the orevactaene/epipyrone biosynthetic gene cluster in Epicoccum nigrum

Bioorganic and Medicinal Chemistry Letters, 2020
Hyung-Jin Kwon, Si-Hyung Park
exaly  

Discovery, Bioactivity Evaluation, Biosynthetic Gene Cluster Identification, and Heterologous Expression of Novel Albofungin Derivatives

Frontiers in Microbiology, 2021
Lan Yi, Wenkang Ye, Cheng Aifang
exaly