Results 141 to 150 of about 177,877 (294)

Bioinformatic mining for RiPP biosynthetic gene clusters in Bacteroidales reveals possible new subfamily architectures and novel natural products [PDF]

, 2023
María Victoria Fernández-Cantos, Diego García-Morena, Yunhai Yi, Lifeng Liang, Emilio Gómez, Oscar P. Kuipers   +5 more
openalex   +1 more source

Hyperandrogenemia Induces Trophoblast Ferroptosis and Early Pregnancy Loss in Patients With PCOS via CMA‐Dependent FTH1 Degradation

Advanced Science, EarlyView.
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou, Weijie Yang, Na Liu, Qing Liu, Jiamin Jin, Chenqiong Zhao, Xiaoying Jin, Miao Gui, Haiyan Zhu, Songying Zhang, Yinli Zhang   +10 more
wiley   +1 more source

Mining metagenomes reveals diverse antibiotic biosynthetic genes in uncultured microbial communities. [PDF]

Braz J Microbiol, 2023
Amin DH, Nageeb WM, Elkelish A, Makharita RR.   +3 more
europepmc   +1 more source

Cloning and Characterization of Two Anthocyanin Biosynthetic Genes from Dendrobium Orchid [PDF]

, 2005
Rasika G. Mudalige–Jayawickrama, Michele Marino Champagne, A. David Hieber, Adelheid R. Kuehnle   +3 more
openalex   +1 more source

2‐line Ferrihydrite Enhance Microbial Synthesis of Plant Biostimulants in Composted Biosolid by Regulating Phyla Pseudomonadota and Actinomycetota

Advanced Science, EarlyView.
This study explores how iron and manganese oxides transform sewage sludge into plant biostimulants during composting. Non‐targeted identification reveals the main species of plant biostimulants. Metagenomic analysis reveals that 2‐line ferrihydrite specifically enriches microbial genes for biosynthesis, boosting plant‐growth promoters.
Yu Zhang, Ziwei Zhang, Zexu Chen, Boyuan Yang, Siying Cai, Jun Chen, Jianhua Guo, Weijun Zhang   +7 more
wiley   +1 more source

Glucosinolate Biosynthetic Genes of Cabbage: Genome-Wide Identification, Evolution, and Expression Analysis. [PDF]

Genes (Basel), 2023
Wang P, Cao W, Yang L, Zhang Y, Fang Z, Zhuang M, Lv H, Wang Y, Cheng S, Ji J.   +9 more
europepmc   +1 more source

Modifying Glucose Metabolism Reverses Memory Defects of Alzheimer's Disease Model at Late Stages

Advanced Science, EarlyView.
Using spatial transcriptomics, we show that ferul enanthate (SL‐ZF‐01) reverses episodic‐like memory deficits in aged, but not young, Alzheimer’s disease (AD) mice. SL restores glucose metabolism and Glucose Transporter 1/3 expression via an ‘Aging‐AD‐Rescue’ pattern, rescuing deficits seen in aged AD mice.
Fang Liu, Yiyu‐Li Tang, Zong‐Bo Zhang, Ya‐Hong Tan, Si‐Hui Lin, Ni‐Ya Wang, Jin‐Nan Li, Zhi‐Jie Pan, Jian‐Feng Li, Jing‐Fei Huang, Yu‐Qiang Ding, Chun‐Ming Guo, Lin Xu, Cheng Peng, Qi‐Xin Zhou   +14 more
wiley   +1 more source

Identification and characterization of a strong constitutive promoter stnYp for activating biosynthetic genes and producing natural products in streptomyces. [PDF]

Microb Cell Fact, 2023
Guo W, Xiao Z, Huang T, Zhang K, Pan HX, Tang GL, Deng Z, Liang R, Lin S.   +8 more
europepmc   +1 more source

Effects of chilling on the expression of ethylene biosynthetic genes in Passe-Crassane pear (Pyrus communis L.) fruits

, 1997
Jean‐Marc Lelièvre, L. Tichit, Patrick Dao, Laurent Fillion, Youngwoo Nam, Jean‐Claude Pech, Alain Lachaux   +6 more
openalex   +2 more sources

Comparative analysis of assembly algorithms to optimize biosynthetic gene cluster identification in novel marine actinomycete genomes

, 2022
Daniela Tizabi, Tsvetan R. Bachvaroff, Russell T. Hill   +2 more
openalex   +1 more source