Results 21 to 30 of about 177,877 (294)
Oxylipin biosynthetic gene families of Cannabis sativa
PLOS ONE, 2023 Cannabis sativa is a global multi-billion-dollar cash crop with numerous industrial uses, including in medicine and recreation where its value is largely owed to the production of pharmacological and psychoactive metabolites known as cannabinoids.
Eli J. Borrego +4 more
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In silico methods for linking genes and secondary metabolites: The way forward
Synthetic and Systems Biotechnology, 2016 In silico methods for linking genomic space to chemical space have played a crucial role in genomics driven discovery of new natural products as well as biosynthesis of altered natural products by engineering of biosynthetic pathways.
Shradha Khater +2 more
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Scientific Reports, 2023 Chrysophaeum taylorii is a member of an understudied clade of marine algae that can be responsible for harmful coastal blooms and is known to accumulate bioactive natural products including antibiotics of the chrysophaentin class. Whole genome sequencing
Jack R. Davison +3 more
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Mining biosynthetic gene clusters in Virgibacillus genomes [PDF]
BMC Genomics, 2019 Biosynthetic gene clusters produce a wide range of metabolites with activities that are of interest to the pharmaceutical industry. Specific interest is shown towards those metabolites that exhibit antimicrobial activities against multidrug-resistant bacteria that have become a global health threat.
Ghofran Othoum +8 more
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Frontiers in Microbiology, 2018 An actinomycete strain, CB-75, was isolated from the soil of a diseased banana plantation in Hainan, China. Based on phenotypic and molecular characteristics, and 99.93% sequence similarity with Streptomyces spectabilis NBRC 13424 (AB184393), the strain ...
Yufeng Chen +6 more
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In silico analyses of maleidride biosynthetic gene clusters
Fungal Biology and Biotechnology, 2022 Maleidrides are a family of structurally related fungal natural products, many of which possess diverse, potent bioactivities. Previous identification of several maleidride biosynthetic gene clusters, and subsequent experimental work, has determined the ‘
Katherine Williams +3 more
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Functional conservation of coenzyme Q biosynthetic genes among yeasts, plants, and humans. [PDF]
PLoS ONE, 2014 Coenzyme Q (CoQ) is an essential factor for aerobic growth and oxidative phosphorylation in the electron transport system. The biosynthetic pathway for CoQ has been proposed mainly from biochemical and genetic analyses of Escherichia coli and ...
Kazuhiro Hayashi +5 more
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A Candidate Gene Cluster for the Bioactive Natural Product Gyrophoric Acid in Lichen-Forming Fungi
Microbiology Spectrum, 2022 Natural products of lichen-forming fungi are structurally diverse and have a variety of medicinal properties. Despite this, they have limited implementation in industry mostly because the corresponding genes are unknown for most of their natural products.
Garima Singh +6 more
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Marine Drugs, 2009 A new strain belonging to the genus Collimonas was isolated from the sea surface microlayer off the coast of Trøndelag, Norway. The bacterium, designated Collimonas CT, produced an antibacterial compound active against Micrococcus luteus.
Sergey B. Zotchev +6 more
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The Biosynthetic Gene Clusters of Aminocoumarin Antibiotics [PDF]
Planta Medica, 2006 Plants and microorganisms are the most important sources of secondary metabolites in nature. For research in the functional genomics of secondary metabolism, and for the biotechnological application of such research by genetic engineering and combinatorial biosynthesis, most microorganisms offer a unique advantage to the researcher: the biosynthetic ...
Shu-Ming, Li, Lutz, Heide
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