Results 51 to 60 of about 1,494 (196)
Photochemical Approaches to Complex Chemotypes: Applications in Natural Product Synthesis. [PDF]
, 2016 The use of photochemical transformations is a powerful strategy that allows for the formation of a high degree of molecular complexity from relatively simple building blocks in a single step. A central feature of all light-promoted transformations is the
Kärkäs, Markus D. +2 more
core +2 more sources
Transcription Factors in Alkaloid Engineering [PDF]
, 2021 Plants produce a large variety of low-molecular-weight and specialized secondary compounds. Among them, nitrogen-containing alkaloids are the most biologically active and are often used in the pharmaceutical industry. Although alkaloid chemistry has been
Sato, Fumihiko, Yamada, Yasuyuki
core +1 more source
Synthesis of Pseudellone Analogs and Characterization as Novel T-type Calcium Channel Blockers
Marine Drugs, 2018 T-type calcium channel (CaV3.x) blockers are receiving increasing attention as potential therapeutics for the treatment of pathophysiological disorders and diseases, including absence epilepsy, Parkinson’s disease (PD), hypertension, cardiovascular
Dan Wang +4 more
doaj +1 more source
Marine Drugs, 2020 Skin is an important barrier to protect the body from environmental stress. However, exposure to ultraviolet radiation (UV) and various environmental oxidative stresses can cause skin inflammation.
Jiyoung Hwang +5 more
doaj +1 more source
Phytochemical and Pharmacological Properties of the Genus Melodinus – A Review [PDF]
, 2016 Melodinus is an important genus comprising of approximately 53 species of medicinal plants (Apocynaceae). Some species have been used in Chinese folk medicine for the treatment of meningitis in children, rheumatic heart diseases, and diuresis, as well as
Chen, Ye-Gao +2 more
core +2 more sources
, 2015 Marine indole alkaloids comprise a large and steadily growing group of secondary metabolites. Their diverse biological activities make many compounds of this class attractive starting points for pharmaceutical development.
Netz, Natalie, Opatz, Till
core +1 more source
Marine Sponge Derived Natural Products between 2001 and 2010: Trends and Opportunities for Discovery of Bioactives [PDF]
, 2014 This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).Abstract: Marine sponges belonging to the phylum Porifera (Metazoa ...
Franco, Christopher Milton +3 more
core +2 more sources
Chapter 3 Noniridoid Bisindole Alkaloids
, 1995 This chapter discusses that indole is a reactive nucleus prone to dimerization when it is isolated or a part of tryptamine or tryptophan, which themselves are reactive toward many functionalities. For these reasons, bisindoles, the majority of which are of iridoid origin, are frequently isolated in nature. Besides these “dimers,” there exists a growing
Sapi, J., Massiot, G.
openaire +1 more source
Fishing for Targets of Alien Metabolites: A Novel Peroxisome Proliferator-Activated Receptor (PPAR) Agonist from a Marine Pest [PDF]
, 2018 Although the chemical warfare between invasive and native species has become a central problem in invasion biology, the molecular mechanisms by which bioactive metabolites from invasive pests influence local communities remain poorly characterized.
Amodeo, Pietro +21 more
core +1 more source
The Raputindoles: Novel Cyclopentyl Bisindole Alkaloids from Raputia simulans
Organic Letters, 2010 A novel class of bisindole alkaloids is established by the isolation and structural determination of raputindoles A-D (1-4) from the Amazonian plant Raputia simulans Kallunki (Rutaceae). Complete spectroscopic characterization was accomplished by means of NMR spectroscopy and APCI (+) HRMS.
Vougogiannopoulou, K. +4 more
openaire +3 more sources