Results 61 to 70 of about 1,584 (196)
Chemistry – A European Journal, Volume 31, Issue 43, August 1, 2025.A library of novel bisindole derivatives was synthesized through an optimized rapid Suzuki‐Miyaura coupling reaction, utilizing NH2‐unprotected bromobisindole ethanamines and boronic acids with yields up to 93%. The compounds were screened for their activity against L. infantum promastigotes.
Alessandro Buono +8 more
wiley +1 more source
MoleculesSynthetic efforts toward complex natural product (NP) scaffolds are useful ones, particularly those aimed at expanding their bioactive chemical space.
Darren C. Holland +3 more
doaj +1 more source
Review: Marine natural products [PDF]
, 2005 This review covers the literature published in 2003 for marine natural products, with 619 citations (413 for the period January to December 2003) referring to compounds isolated from marine microorganisms and phytoplankton, green algae, brown algae, red ...
Blunt, John W. +4 more
core +3 more sources
Plant-derived antimalarial agents: from crude extracts to isolated bioactive compounds [PDF]
, 2011 Despite decades of intense research, malaria remains a deadly disease of the developing worlds. Drugresistance to limited available antimalarials, in part, has contributed to the persistence of this infectious disease.
Abdullah, Wan Omar, Ismail, Patimah
core
Cyclopropanation of Some Alkaloids [PDF]
, 2015 New derivatives of natural compounds, galanthamine using in treatment of Alzheimer’s disease and antitumor dimer alkaloids vinblastine and vincristine were synthesized.
Hazai, László +3 more
core +2 more sources
From data to discovery: leveraging big data in plant natural products biosynthesis research
The Plant Journal, Volume 122, Issue 6, June 2025.SUMMARY Plant natural products or specialized metabolites play a vital role in drug discovery and development, with many clinically important derivatives such as the anticancer drugs topotecan (derived from the natural alkaloid camptothecin) and etoposide (derived from the natural polyphenol podophyllotoxin).
Matthew McConnachie +4 more
wiley +1 more source
Indole alkaloids from marine sources as ootential leads againstinfectious diseases [PDF]
, 2014 Indole alkaloids comprise a large and complex class of natural products found in a variety of marine sources. Infectious diseases remain a major threat to public health, and in the absence of long-term protective vaccines, the control of these infectious
Araújo Júnior, João Xavier de +10 more
core +1 more source
Food Science &Nutrition, Volume 12, Issue 12, Page 9951-9973, December 2024.This study discussed the therapeutic capacity of various polyphenols, terpenoids, and alkaloids on CRC via the PI3K/Akt/mTOR pathway. Each bioactive component causes various physiological processes, such as triggering free radical production, disruption of mitochondrial membrane potential, cell cycle arrest, inhibition of CRC stem cell migration ...
Kübra Demir +4 more
wiley +1 more source
Screening for Bioactive Compounds from Algae [PDF]
, 2012 At present, functional foods are seen as a good alternative to maintain or even improve human health, mainly for the well-known correlation between diet and health.
Herrero, Miguel +3 more
core +2 more sources
Mechanochemistry in Organic Synthesis: An Italian Journey through Innovations
European Journal of Organic Chemistry, Volume 27, Issue 30, August 12, 2024.The contribution of Italy to the development of mechanochemistry dates back to 1988 with the first studies on metal alloys. With the progress of time, it has flourished not only in the field of organic chemistry, but also in other scientific fields due to the enormous interest of Italian researchers in the various advantages brought by this technique ...
Francesco Basoccu +2 more
wiley +1 more source