Results 11 to 20 of about 36,968 (260)

Bisphosphonates for osteoarthritis [PDF]

open access: yesArthritis Research & Therapy, 2011
Synovitis and subchondral bone turnover are associated with pain in osteoarthritis. Bisphosphonates provide tools for investigating these pathogenic mechanisms and also may have therapeutic potential. Translating preclinical findings into new treatments for human osteoarthritis requires a critical appraisal and refinement of animal models ...
Walsh, David A, Chapman, Victoria
openaire   +2 more sources

Bisphosphonates Target B Cells to Enhance Humoral Immune Responses

open access: yesCell Reports, 2013
Bisphosphonates are a class of drugs that are widely used to inhibit loss of bone mass in patients. We show here that the administration of clinically relevant doses of bisphosphonates in mice increases antibody responses to live and inactive viruses ...
Elena Tonti   +14 more
doaj   +1 more source

Bisphosphonates

open access: yesTurkish Journal of Orthodontics, 2009
Bisphosphonates are used with the purpose of preventing bone resorption in some metabolic bone diseases. These drugs have been introduced into clinical use about 30 years ago and widely used in nowadays. As Orthodontic some different researches have been
Fırat Öztürk
doaj   +1 more source

Bisphosphonates and Cancer [PDF]

open access: yesJournal of Veterinary Internal Medicine, 2004
Abstract Bisphosphonates form a family of drugs characterized pharmacologically by their ability to inhibit bone resorption and pharma-cokinetically by similar intestinal absorption, skeletal distribution, and renal elimination. Two groups of bisphosphonates exist chemically, non-amino-bisphosphates and amino-bisphosphonates.
Rowan J, Milner   +5 more
openaire   +2 more sources

Evaluation of trabecular bone changes according to the type of prosthesis in patients using bisphosphonates: a retrospective study [PDF]

open access: yesBrazilian Oral Research, 2023
The objective of the study was to retrospectively compare the fractal size values calculated in the trabecular bone according to the type of complete removable denture, removable partial denture, and partial fixed prosthesis between patients using ...
Begüm Ünlü Kurşun, Ender Akan
doaj   +1 more source

Bisphosphonates and Atypical Hip Fractures: Current Status of Issue and Answers to Discussion Questions

open access: yesBolʹ, Sustavy, Pozvonočnik, 2012
The paper presents the recent data with the literature review on the controversial issue of the link between chronic administration of bisphosphonates, and atypical femoral shaft fractures.
I.Yu. Golovach
doaj   +1 more source

The incidence and relative risk of adverse events in patients treated with bisphosphonate therapy for breast cancer: a systematic review and meta-analysis

open access: yesTherapeutic Advances in Medical Oncology, 2019
Background: Adjuvant bisphosphonates reduce the rate of breast cancer recurrence in the bone and improve breast cancer survival. However, the risk of adverse events associated with bisphosphonate therapy for breast cancer remains poorly defined. Methods:
Yan-Li Yang   +4 more
doaj   +1 more source

Adherence to Bisphosphonates among People Admitted to an Orthopaedic and Geriatric Ward at a University Hospital in Sweden

open access: yesPharmacy, 2018
Oral bisphosphonates are the first choice of therapy to reduce the risk of osteoporotic fractures. These medications have generally poor oral bioavailability, which may further be reduced by concomitant intake of certain foods and drugs; therefore, it is
Linnea Abramsson, Maria Gustafsson
doaj   +1 more source

Pharmacology of bisphosphonates [PDF]

open access: yesBritish Journal of Clinical Pharmacology, 2019
The biological effects of the bisphosphonates (BPs) as inhibitors of calcification and bone resorption were first described in the late 1960s. In the 50 years that have elapsed since then, the BPs have become the leading drugs for the treatment of skeletal disorders characterized by increased bone resorption, including Paget's disease of bone, bone ...
Cremers, S.   +4 more
openaire   +3 more sources

Long Term Bisphosphonate Use in Osteoporotic Patients; A Step Forward, Two Steps Back

open access: yesJournal of Pharmacy & Pharmaceutical Sciences, 2012
Purpose. Bisphosphonates are the main class of drugs widely used in prevention and treatment of osteoporosis. Along with the beneficial effects, recent studies point to the harms of long-term treatment with bisphosphonates. Methods.
Pooneh Salari, Mohammad Abdollahi
doaj   +1 more source

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