Results 11 to 20 of about 52,862 (295)

Bisphosphonates: An update

Journal of Pharmacy and Bioallied Sciences, 2012
Bisphosphonates are used widely for variety of bone condition, most notably IV bisphosphonates in the treatment of metastic bone lesion and oral bisphosphonates for osteoporosis.
Nalliappan Ganapathy, Subramanium Gokulnathan, Nataraj Balan, Thangadurai Maheswaran, Venkatesan   +4 more
doaj   +4 more sources

Bisphosphonates and osteonecrosis of jaws

Journal of Indian Academy of Oral Medicine and Radiology, 2012
Bisphosphonates are used to treat osteoporosis. Paget disease of bone and other metabolic bone diseases, multiple myeloma, and skeletal events associated with metastatic neoplasms- In 2003, the first reports describing osteonecrosis of the jaw (ONJ) in ...
Geetha Vijay, Vijay Raghavan
doaj   +2 more sources

Therapeutic potential of bisphosphonates - review of medical indications, mechanism of action, interactions and adverse effects [PDF]

Journal of Education, Health and Sport
Introduction: Bisphosphonates are pharmacological agents that inhibit bone resorption by targeting osteoclasts, thereby increasing bone density and reducing fracture risk.
Agnieszka Mikosińska, Mateusz Litwin, Jakub Parys, Patrycja Kałuziak, Aleksandra Witek, Martyna Kaźmierczak, Stanisław Jesionek, Marta Jajczak, Maciej Mossakowski   +8 more
doaj   +2 more sources

The survey of anti-inflammatory effect of bisphosphonates

Journal of Mazandaran University of Medical Sciences, 2009
(Received 13 Dec, 2008 ; Accepted 28 Jan, 2009)AbstractBisphosphonates are currently used in metabolic disorder of bone; however, there have been few studies that reviewed the role of anti-inflammatory and immune modulatory effect of this agent in in ...
Reza Shiari, Mohammad Mehdi Nasehi, Shervin Farivar, Bijan Hatamian   +3 more
doaj   +1 more source

Influence on persistence and adherence with oral bisphosphonates on fracture rates in osteoporosis

Patient Preference and Adherence, 2008
Ariane Höer1, Cornelia Seidlitz1, Holger Gothe1, Guido Schiffhorst1, Melvin Olson2, Peyman Hadji3, Bertram Häussler11IGES Institut, Friedrichstrasse 180, D-10117 Berlin, Germany; 2Novartis Pharma AG; 3Department of Gynaecology ...
Ariane Höer, Cornelia Seidlitz, Holger Gothe, Guido Schiffhorst, Melvin Olson, et al   +5 more
doaj   +1 more source

Safety of bisphosphonates

Bone, 2011
Bisphosphonates are one of the most well studied groups of medications and they are bone specific. This tissue specificity is a rare property for a drug introduced into clinical practice as long as 40 years ago. Over the years, the therapeutic boundaries of bisphosphonates were explored and their safety profile has withstood the challenges of the harsh
Pazianas, Michael, Abrahamsen, Bo
openaire   +4 more sources

Bisphosphonates [PDF]

Endocrinology and Metabolism Clinics of North America, 2003
Osteoporosis is the result of bone loss due to an imbalance in bone turnover such that bone resorption exceeds bone formation. Bisphosphonates are potent inhibitors of osteoclast activity that reduce bone turnover and re-establish the balance between bone resorption and formation. In clinical studies, several bisphosphonates prevent bone loss, preserve
Julie T, Lin, Joseph M, Lane
openaire   +7 more sources

Bisphosphonates for Osteoporosis [PDF]

New England Journal of Medicine, 2011
One in three women and at least one in 12 men in the UK have osteoporosis, a condition which can lead to fractures, deformity, pain and disability, at a cost to the NHS of around £1.5 billion each year.1,2 Bisphosphonates offer a therapeutic option for preventing and treating osteoporosis.
Vis, M., Dijkmans, B.A.C., Lems, W.F.
  +9 more sources

Bisphosphonates and Cancer [PDF]

Journal of Veterinary Internal Medicine, 2004
Abstract Bisphosphonates form a family of drugs characterized pharmacologically by their ability to inhibit bone resorption and pharma-cokinetically by similar intestinal absorption, skeletal distribution, and renal elimination. Two groups of bisphosphonates exist chemically, non-amino-bisphosphates and amino-bisphosphonates.
Rowan J, Milner, James, Farese, Carolyn J, Henry, Kim, Selting, Timothy M, Fan, Louis-Philippe, de Lorimier   +5 more
openaire   +2 more sources

Oral Bisphosphonates and Risk of Atrial Fibrillation and Flutter in Women: A Self-Controlled Case-Series Safety Analysis [PDF]

, 2009
Background: A recent trial unexpectedly reported that atrial fibrillation, when defined as serious, occurred more often in participants randomized to an annual infusion of the relatively new parenteral bisphosphonate, zoledronic acid, than among those ...
Aroon Hingorani, Douglas, I, Hingorani, A, Douglas, Ian, MacAllister, Raymond, Grosso, Anthony, MacAllister, R, Anthony Grosso, Liam Smeeth, Smeeth, Liam, Raymond MacAllister, Grosso, A, Smeeth, L, Ian Douglas, Hingorani, Aroon   +14 more
core   +1 more source