Results 31 to 40 of about 52,862 (295)

Oral Mucosal Ulcer Associated with Improper Usage of Bisphosphonate: A Case Report

open access: yesTürk Osteoporoz Dergisi, 2023
Bisphosphonates are widely used agents for osteoporosis. Although bisphosphonates are generally well-tolerated drugs, especially oral forms may have gastrointestinal system side effects.
Şeyma Nur Bayındır   +2 more
doaj   +1 more source

Decrease in outpatient department visits and operative interventions due to bisphosphonates in children with osteogenesis imperfecta

open access: yesJournal of Children's Orthopaedics, 2011
Introduction Bisphosphonates are currently the medical treatment most often used in children with osteogenesis imperfecta (OI). The purpose of this retrospective pre–post study was to evaluate the efficacy of treatment with bisphosphonates.
F. de Graaff   +3 more
doaj   +1 more source

Osteonecrose da mandíbula associada a bifosfonatos intravenosos em doentes oncológicos.

open access: yesActa Médica Portuguesa, 2008
Bisphosphonates are synthetic analogs of inorganic pyrophosphate, which are not only potent inhibitors of osteoclast-mediated bone resorption, but also present an important inhibitory activity of angiogenesis.
Ana Carvalho   +3 more
doaj   +1 more source

ATYPICAL FRACTURES DUE TO LONG TREATMENT WITH BISPHOSPHONATES (CRITICAL REVIEW)

open access: yesTravmatologiâ i Ortopediâ Rossii, 2013
This paper reviews the evidence for an association between atypical subtrochanteric fractures and long-term bisphosphonate use. A PubMed search of literature was performed.
G. S. Golubev
doaj   +1 more source

Changes in the utilization of osteoporosis drugs after the 2010 FDA bisphosphonate drug safety communication

open access: yesSaudi Pharmaceutical Journal, 2018
Introduction: In October 2010, the US Food and Drug Administration (FDA) issued a safety communication regarding the risks of atypical fractures of the femur, with bisphosphonates drugs.
Bander Balkhi   +2 more
doaj   +1 more source

Comparing Efficacy of Denosumab to Bisphosphonates in Fragility Fractures [PDF]

open access: yes, 2022
Background: Osteoporosis is a disease of the bones with decreased bone mineral density and bone mass, leading to poor bone quality/structure, increasing the risk of fragility fractures.
Cardoso, Ronald Toledo
core   +1 more source

The Effects of Low-Dose Bisphosphonate Treatment on Bone Mineral Density and Bone Turnover Markers in Elderly Patients With Osteoporosis

open access: yesAnnals of Geriatric Medicine and Research, 2016
Background: Osteoporosis is commonly treated with bisphosphonates. These drugs promote osteoclast apoptosis, which suppresses bone resorption. However, the probability of side effects increases with long-term use of bisphosphonates.
Seo Young Lee   +7 more
doaj   +1 more source

Bisphosphonates for osteoarthritis [PDF]

open access: yesArthritis Research & Therapy, 2011
Synovitis and subchondral bone turnover are associated with pain in osteoarthritis. Bisphosphonates provide tools for investigating these pathogenic mechanisms and also may have therapeutic potential. Translating preclinical findings into new treatments for human osteoarthritis requires a critical appraisal and refinement of animal models ...
Walsh, David A, Chapman, Victoria
openaire   +2 more sources

Differential effects of bisphosphonates on breast cancer cell lines [PDF]

open access: yes, 2007
Bisphosphonates may induce direct anti-tumor effects in breast cancers cells in virtro. In this study, six bisphosphonates were administered to three breast caner cell lines.
Franke, H.R.   +3 more
core   +1 more source

Macrophage–Fibroblast Crosstalk Governs Tumor Mechanics, as Revealed by Spatiotemporal Force Mapping in 3D Spheroids

open access: yesAdvanced Healthcare Materials, EarlyView.
This study shows crosstalk among tumor cells, fibroblasts, and macrophages alters the physical forces inside 3D tumor spheroids. Incorporating deformable microparticles in 3D tumor spheroids, the researchers mapped mechanical stresses spatially and with respect to tumor growth (temporally).
Kunal P. Pednekar   +2 more
wiley   +1 more source

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