Results 21 to 30 of about 37,214 (250)

Decrease in outpatient department visits and operative interventions due to bisphosphonates in children with osteogenesis imperfecta

open access: yesJournal of Children's Orthopaedics, 2011
Introduction Bisphosphonates are currently the medical treatment most often used in children with osteogenesis imperfecta (OI). The purpose of this retrospective pre–post study was to evaluate the efficacy of treatment with bisphosphonates.
F. de Graaff   +3 more
doaj   +1 more source

Osteonecrose da mandíbula associada a bifosfonatos intravenosos em doentes oncológicos.

open access: yesActa Médica Portuguesa, 2008
Bisphosphonates are synthetic analogs of inorganic pyrophosphate, which are not only potent inhibitors of osteoclast-mediated bone resorption, but also present an important inhibitory activity of angiogenesis.
Ana Carvalho   +3 more
doaj   +1 more source

Use of bisphosphonates in bone pathology – benefits and risks [PDF]

open access: yesRomanian Journal of Rheumatology, 2023
This article aims to establish, on the basis of medical literature and of the authors’ experience, whether bisphosphonates still have a role in treating skeletal diseases, with increased bone resorption. The effects of bisphosphonates on the bone tissue,
Dinu Antonescu, Cristian Ioan Stoica
doaj   +1 more source

Oral Mucosal Ulcer Associated with Improper Usage of Bisphosphonate: A Case Report

open access: yesTürk Osteoporoz Dergisi, 2023
Bisphosphonates are widely used agents for osteoporosis. Although bisphosphonates are generally well-tolerated drugs, especially oral forms may have gastrointestinal system side effects.
Şeyma Nur Bayındır   +2 more
doaj   +1 more source

Pharmacology of bisphosphonates [PDF]

open access: yesBritish Journal of Clinical Pharmacology, 2019
The biological effects of the bisphosphonates (BPs) as inhibitors of calcification and bone resorption were first described in the late 1960s. In the 50 years that have elapsed since then, the BPs have become the leading drugs for the treatment of skeletal disorders characterized by increased bone resorption, including Paget's disease of bone, bone ...
Cremers, S.   +4 more
openaire   +3 more sources

Therapeutic potential of bisphosphonates - review of medical indications, mechanism of action, interactions and adverse effects

open access: yesJournal of Education, Health and Sport
Introduction: Bisphosphonates are pharmacological agents that inhibit bone resorption by targeting osteoclasts, thereby increasing bone density and reducing fracture risk.
Agnieszka Mikosińska   +8 more
doaj   +1 more source

BISPHOSPHONATE INDUCED OSTEONECROSIS OF THE JAWS AND CURRENT THERAPIES

open access: yesCumhuriyet Dental Journal, 2017
Bisphosphonates are pharmacological agents which are the potent inhibitors of osteoclastic activity. Nowadays, bisphosphonates are used to treat a variety of bone disease or related complications such as metastatic or osteolytic bone disease ...
Damla Torul, Mehmet Cihan Bereket
doaj   +1 more source

Bisphosphonates for osteoarthritis [PDF]

open access: yesArthritis Research & Therapy, 2011
Synovitis and subchondral bone turnover are associated with pain in osteoarthritis. Bisphosphonates provide tools for investigating these pathogenic mechanisms and also may have therapeutic potential. Translating preclinical findings into new treatments for human osteoarthritis requires a critical appraisal and refinement of animal models ...
Walsh, David A, Chapman, Victoria
openaire   +2 more sources

ATYPICAL FRACTURES DUE TO LONG TREATMENT WITH BISPHOSPHONATES (CRITICAL REVIEW)

open access: yesTravmatologiâ i Ortopediâ Rossii, 2013
This paper reviews the evidence for an association between atypical subtrochanteric fractures and long-term bisphosphonate use. A PubMed search of literature was performed.
G. S. Golubev
doaj   +1 more source

Bisphosphonates and osteonecrosis of jaws

open access: yesJournal of Indian Academy of Oral Medicine and Radiology, 2012
Bisphosphonates are used to treat osteoporosis. Paget disease of bone and other metabolic bone diseases, multiple myeloma, and skeletal events associated with metastatic neoplasms- In 2003, the first reports describing osteonecrosis of the jaw (ONJ) in ...
Geetha Vijay, Vijay Raghavan
doaj   +1 more source

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