Results 21 to 30 of about 37,214 (250)
Introduction Bisphosphonates are currently the medical treatment most often used in children with osteogenesis imperfecta (OI). The purpose of this retrospective pre–post study was to evaluate the efficacy of treatment with bisphosphonates.
F. de Graaff +3 more
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Osteonecrose da mandíbula associada a bifosfonatos intravenosos em doentes oncológicos.
Bisphosphonates are synthetic analogs of inorganic pyrophosphate, which are not only potent inhibitors of osteoclast-mediated bone resorption, but also present an important inhibitory activity of angiogenesis.
Ana Carvalho +3 more
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Use of bisphosphonates in bone pathology – benefits and risks [PDF]
This article aims to establish, on the basis of medical literature and of the authors’ experience, whether bisphosphonates still have a role in treating skeletal diseases, with increased bone resorption. The effects of bisphosphonates on the bone tissue,
Dinu Antonescu, Cristian Ioan Stoica
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Oral Mucosal Ulcer Associated with Improper Usage of Bisphosphonate: A Case Report
Bisphosphonates are widely used agents for osteoporosis. Although bisphosphonates are generally well-tolerated drugs, especially oral forms may have gastrointestinal system side effects.
Şeyma Nur Bayındır +2 more
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Pharmacology of bisphosphonates [PDF]
The biological effects of the bisphosphonates (BPs) as inhibitors of calcification and bone resorption were first described in the late 1960s. In the 50 years that have elapsed since then, the BPs have become the leading drugs for the treatment of skeletal disorders characterized by increased bone resorption, including Paget's disease of bone, bone ...
Cremers, S. +4 more
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Introduction: Bisphosphonates are pharmacological agents that inhibit bone resorption by targeting osteoclasts, thereby increasing bone density and reducing fracture risk.
Agnieszka Mikosińska +8 more
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BISPHOSPHONATE INDUCED OSTEONECROSIS OF THE JAWS AND CURRENT THERAPIES
Bisphosphonates are pharmacological agents which are the potent inhibitors of osteoclastic activity. Nowadays, bisphosphonates are used to treat a variety of bone disease or related complications such as metastatic or osteolytic bone disease ...
Damla Torul, Mehmet Cihan Bereket
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Bisphosphonates for osteoarthritis [PDF]
Synovitis and subchondral bone turnover are associated with pain in osteoarthritis. Bisphosphonates provide tools for investigating these pathogenic mechanisms and also may have therapeutic potential. Translating preclinical findings into new treatments for human osteoarthritis requires a critical appraisal and refinement of animal models ...
Walsh, David A, Chapman, Victoria
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ATYPICAL FRACTURES DUE TO LONG TREATMENT WITH BISPHOSPHONATES (CRITICAL REVIEW)
This paper reviews the evidence for an association between atypical subtrochanteric fractures and long-term bisphosphonate use. A PubMed search of literature was performed.
G. S. Golubev
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Bisphosphonates and osteonecrosis of jaws
Bisphosphonates are used to treat osteoporosis. Paget disease of bone and other metabolic bone diseases, multiple myeloma, and skeletal events associated with metastatic neoplasms- In 2003, the first reports describing osteonecrosis of the jaw (ONJ) in ...
Geetha Vijay, Vijay Raghavan
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