Results 41 to 50 of about 51,509 (201)

How Do Bisphosphonates Inhibit Bone Metastasis In Vivo? [PDF]

, 2010
"Bisphosphonates are potent inhibitors of osteoclast-mediated bone resorption and have demonstrated clinical utility in the treatment of patients with osteolytic bone metastases.
PIERRICK GERARD JEAN FOURNIER
core   +1 more source

Bisphosphonate-related bilateral atypical femoral fractures : be aware and beware [PDF]

, 2011
Although bisphosphonates have a well established therapeutic role in the prevention of osteoporosis-related fractures, several reports published over the past 5-6 years suggest a possible causative relationship between long-term use of bisphosphonates ...
Depasquale, Ruben, Matthews, Claire, Cassar-Pullicino, Victor N.   +2 more
core  

Denosumab compared to bisphosphonates to treat postmenopausal osteoporosis: a meta-analysis

Journal of Orthopaedic Surgery and Research, 2018
Background The standard treatment for osteoporosis was controversial. Denosumab and bisphosphonates were two most common drugs. The purpose of this study was to compare the efficacy and safety of denosumab with bisphosphonates to treat osteoporosis ...
Jiaqi Wu, Qingsheng Zhang, Guanghui Yan, Xianhui Jin   +3 more
doaj   +1 more source

Bisphosphonates in Total Joint Arthroplasty: A Review of Their Use and Complications

Arthroplasty Today, 2022
Background: Considerable interest has been expressed in the use of bisphosphonates to treat periprosthetic osteoporosis with the clinical goals of reducing periprosthetic fractures and prolonging implant survival.
Christopher L. McDonald, MD, Nicholas J. Lemme, MD, Edward J. Testa, MD, Roy Aaron, MD, Davis A. Hartnett, BS, Eric M. Cohen, MD   +5 more
doaj   +1 more source

The survey of anti-inflammatory effect of bisphosphonates

Journal of Mazandaran University of Medical Sciences, 2009
(Received 13 Dec, 2008 ; Accepted 28 Jan, 2009)AbstractBisphosphonates are currently used in metabolic disorder of bone; however, there have been few studies that reviewed the role of anti-inflammatory and immune modulatory effect of this agent in in ...
Reza Shiari, Mohammad Mehdi Nasehi, Shervin Farivar, Bijan Hatamian   +3 more
doaj  

Bisphosphonates

, 2013
Over the 40-year period during which bisphosphonates have been used in clinical practice, the mechanism of action for both simple and nitrogen-containing compounds has become clear, although sources variation in individual response still requires further
Bishop, NJ, Russell, G, Russell, Graham
core   +1 more source

Bone Healing After Tooth Extraction in a Patient on Oral Bisphosphonates: A Case Report

Osteology
Background: The present case report study aims to describe, from both clinical and histological aspects, the bone healing pattern in a patient under oral bisphosphonates therapy.
Antonello Falco, Lorenzo Vittorini Orgeas, Roberta Di Pietro, Loredana Masciotra, Sergio Rexhep Tari, Calogero Bugea, Antonio Scarano   +6 more
doaj   +1 more source

The impact of vitamin D status on changes in bone mineral density during treatment with bisphosphonates and after discontinuation following long-term use in post-menopausal osteoporosis

BMC Musculoskeletal Disorders, 2007
Background It is still unclear whether addition of calcium/vitamin D supplements leads to an incremental benefit in patients taking bisphosphonates and whether achievement of serum level of 25 (OH) vitamin D of at least 70 nmol/L has an impact on the ...
Fogelman Ignac, Constancio Leonor, Deane Andrew, Hampson Geeta   +3 more
doaj   +1 more source

Comparison of denosumab and oral bisphosphonates for the treatment of glucocorticoid-induced osteoporosis: a systematic review and meta-analysis

BMC Musculoskeletal Disorders, 2022
Background Both denosumab and bisphosphonates have been demonstrated effective for glucocorticoid-induced osteoporosis. However, evidence-based medicine is still lacking to prove the clinical results between denosumab and bisphosphonates.
Lianghai Jiang, Jian Dong, Jianwei Wei, Lantao Liu   +3 more
doaj   +1 more source

The Role of Biphosphonate and Denosumab in Bone Metastasis

Indonesian Journal of Cancer
Metastasis is a major contributor to cancer-related morbidity and mortality. Bone metastasis is prevalent and associated with pain and fractures, particularly in breast cancer where up to 80% of patients may be affected. Bisphosphonates, traditional anti-
Rahmat Cahyanur, Aravinda Pravita
doaj   +1 more source