Results 11 to 20 of about 61,588 (194)
BK polyomavirus: latency, reactivation, diseases and tumorigenesis
Frontiers in Cellular and Infection Microbiology, 2023 The identification of the first human polyomavirus BK (BKV) has been over half century, The previous epidemiological and phylogenetic studies suggest that BKV prevailed and co-evolved with humans, leading to high seroprevalence all over the world.
Xianfeng Zhou, Chunlong Zhu, Hui Li
semanticscholar +4 more sources
BK Polyomavirus-Induced Nephropathy in Native Kidney
Cureus, 2023 BK polyomavirus has been well-studied as an opportunistic infection in immunocompromised kidney transplant patients. In the majority of the population, BK polyomavirus establishes a lifelong infection in renal tubular and uroepithelial cells; however, in
Ripudaman Munjal +3 more
semanticscholar +3 more sources
Optimized amplification of BK polyomavirus in urine.
Journal of Virological Methods, 2021 BK polyomavirus (BKPyV) is a ubiquitous pathogen that typically results in asymptomatic infection. However, in immunocompromised individuals, BKPyV viral shedding in the urine can reach 109 copies per mL.
Elizabeth A. Odegard +9 more
semanticscholar +4 more sources
BK polyomavirus diversity—Why viral variation matters
Reviews in Medical Virology, 2020 BK polyomavirus (BKPyV or BKV) is a non‐enveloped, circular double‐stranded DNA virus that may exceed 80% seroprevalence in adults. BKV infection typically occurs during childhood, and the majority of adults are latently infected.
J. Blackard, S. Davies, B. Laskin
semanticscholar +4 more sources
HLA-B Leader Dimorphism Predicts BK Polyomavirus Replication After Kidney Transplant. [PDF]
HLAABSTRACT BK polyomavirus (BKPyV) and Cytomegalovirus (CMV) often replicate after kidney transplantation, with management limited to reducing immunosuppression and risking rejection. Among genetic factors that may modulate the antiviral response, HLA evolutionary divergence (HED, allowing a greater diversity of antigen presentation) and the HLA‐B leader
Aubry A +7 more
europepmc +2 more sources
BK Polyomavirus and Transformation [PDF]
American Journal of Transplantation, 2011 The human BK polyomavirus (PyV) (BKV) was isolated from the urine of a kidney transplant patient with the initials B.K. after cells with nuclear atypia were noted in the urine in the diagnostic workup of an alloureter stenosis. Electron microscopy revealed intranuclear inclusions of nonenveloped viral particles of 40–45-nm diameter suggesting infection
Tina Dalianis, Hans H. Hirsch
openaire +4 more sources
PLoS ONE, 2023 BK polyomavirus-associated nephropathy occurs in kidney transplant recipients under immunosuppressive treatment. BK polyomavirus is implicated in cancer development and invasion, and case reports of renal cell carcinoma and urothelial carcinoma possibly ...
Noriaki Sato +8 more
doaj +1 more source
BK polyomavirus: emerging pathogen [PDF]
Microbes and Infection, 2012 BK polyomavirus (BKPyV) is a small double-stranded DNA virus that is an emerging pathogen in immunocompromised individuals. BKPyV is widespread in the general population, but primarily causes disease when immune suppression leads to reactivation of latent virus.
Shauna M, Bennett +2 more
openaire +2 more sources
Kidney International Reports, 2022 Introduction BK polyomavirus-associated nephropathy (BKPyVAN) is associated with graft dysfunction and loss; however, knowledge of immunosuppression reduction strategies and long-term graft, and patient outcomes across the disease spectrum is lacking ...
Ryan P Gately +9 more
semanticscholar +1 more source
Cytomegalovirus and polyomavirus BK posttransplant [PDF]
Nephrology Dialysis Transplantation, 2007 Virus replication and progression to disease in transplant patients is determined by patient-, graft- and virus-specific factors. This complex interaction is modulated by the net state of immunosuppression and its impact on virus-specific cellular immunity.
Egli, Adrian +8 more
openaire +4 more sources