Results 21 to 30 of about 61,588 (194)
International Journal of Molecular Sciences, 2022 Background: Bkv-miR-B1-5p is a viral micro-RNA (miRNA) specifically produced during BK polyomavirus (BKPyV) replication. Recent studies have suggested using bkv-miR-B1-5p as a biomarker to monitor viral infection and predict complications in kidney ...
Baptiste Demey +7 more
semanticscholar +1 more source
Oncogene, 2022 Limited understanding of bladder cancer aetiopathology hampers progress in reducing incidence. Mutational signatures show the anti-viral apolipoprotein B mRNA editing enzyme catalytic polypeptide (APOBEC) enzymes are responsible for the preponderance of ...
S. Baker +10 more
semanticscholar +1 more source
Regulation of Virus Replication by BK Polyomavirus Small T Antigen
Journal of Virology, 2023 BK polyomavirus is a virus that establishes a lifelong infection of the majority of people. The infection usually does not cause any clinical symptoms, but, in transplant recipients whose immune systems have been suppressed, unchecked virus replication ...
W. Zou, M. Imperiale
semanticscholar +1 more source
Transplantation Reports, 2021 Introduction: : BK polyoma virus nephropathy represents one of the non-immunological causes of renal graft loss with a cumulative incidence between 5 and 10 percent, and a graft loss rate on BK virus nephropathy patients that ranges from 30 to 90 percent
Rodolfo Torres +7 more
doaj +1 more source
BK Polyomavirus Nephropathy in Kidney Transplantation: Balancing Rejection and Infection
Viruses, 2021 BK polyomavirus nephropathy (BKVN) and allograft rejection are two closely-associated diseases on opposite ends of the immune scale in kidney transplant recipients. The principle of balancing the immune system remains the mainstay of therapeutic strategy.
Chia-Lin Shen +4 more
semanticscholar +1 more source
Levels of donor‐derived cell‐free DNA and chemokines in BK polyomavirus‐associated nephropathy
Clinical Transplantation, 2022 BK polyomavirus‐associated nephropathy (BKPyVAN) carries a risk of irreversible allograft injury. While detection of BK viremia and biopsy assessment are the current diagnostic gold standard, the diagnostic value of biomarkers reflecting tissue injury ...
Katharina A Mayer +14 more
semanticscholar +1 more source
BK Polyomavirus in Solid Organ Transplantation [PDF]
American Journal of Transplantation, 2013 The human BK polyomavirus (BKV) is the major cause of polyomavirus-associated nephropathy (PyVAN) putting 1-15% of kidney transplant patients at risk of premature allograft failure, but is less common in other solid organ transplants. Because effective antiviral therapies are lacking, screening kidney transplant patients for BKV replication in urine ...
Hirsch, H. H., Randhawa, P.
openaire +3 more sources
Acute Kidney Injury and BK Polyomavirus in Urine Sediment Cells
International Journal of Molecular Sciences, 2023 Polyomaviruses are widespread, with BK viruses being most common in humans who require immunosuppression due to allotransplantation. Infection with BK polyomavirus (BKV) may manifest as BK virus-associated nephropathy and hemorrhagic cystitis ...
S. Pajenda +9 more
semanticscholar +1 more source
Native BK Polyomavirus Nephropathy in an Orthotopic Heart Transplant Patient
Journal of Investigative Medicine High Impact Case Reports, 2023 BK polyomavirus nephropathy (BKVN) is a common cause of nephropathy in kidney transplant patients and is typically seen within the first year after transplantation.
Zachary M. Thompson MD +5 more
doaj +1 more source
Viruses, 2022 The BK polyomavirus (BKPyV) is a widespread pathogen in humans. Polymorphism of the region encoding the VP1 protein of BKPyV provides the basis for classifying the virus into types and subtypes, whose frequency varies depending on geographic location ...
J. Furmaga +7 more
semanticscholar +1 more source