Results 41 to 50 of about 61,588 (194)

Molecular Characterization of BK Polyomavirus Replication in Allogeneic Hematopoietic Cell Transplantation Patients

Journal of Infectious Diseases, 2022
Background High-level BK polyomavirus (BKPyV) replication in allogeneic hematopoietic cell transplantation (HCT) predicts failing immune control and BKPyV-associated hemorrhagic cystitis.
K. Leuzinger, A. Kaur, Maud Wilhelm, Konstantin Frank, Carolin Hillenbrand, F. Weissbach, H. Hirsch   +6 more
semanticscholar   +1 more source

Persistently high-level polyomavirus BK replication in the absence of renal function abnormalities in a kidney transplant recipient

Microbiologia Medica, 2016
Polyomavirus-associated nephropathy is an important cause of allograft dysfunction and graft loss after kidney transplantation. Even if histological evaluation is the gold standard for graft study and diagnosis of polyomavirus-associated nephropathy, K ...
Antonio Curtoni, Cristina Costa, Maria Messina, Francesca Sidoti, Andrea Piceghello, Gabriele Bianco, Luigi Biancone, Giuseppe Paolo Segoloni, Rossana Cavallo   +8 more
doaj   +1 more source

Research progress in BK polyomavirus nephropathy [PDF]

Jichu yixue yu linchuang
BK polyomavirus (BKPyV) typically enters host cells through caveolin-mediated endocytosis or clathrin-independent vesicle encapsulation, maintaining clinical latency without symptomatic manifestations.
YANG Dan, YANG Feng
doaj   +1 more source

Everolimus reduces BK polyomavirus infection by suppressing its replication and spread of infection.

Antiviral Research, 2022
BK polyomavirus-associated nephropathy is one of serious complications in transplant recipients. Everolimus-a mammalian target of rapamycin inhibitor-has been shown to reduce the incidence of BK polyomavirus infection in transplant recipients.
Noriaki Sato, Atsuko Shiraki, Keita P. Mori, K. Sakai, Long Tan, Yoshinori Takemura, Yasushi Okuno, K. Tanabe, K. Shiraki   +8 more
semanticscholar   +1 more source

The Potential Role of BK and JC Polyomaviruses in Urothelial Cancer

The Iraqi Journal of Medical Sciences
Background:    BK and JC polyomaviruses are perceived as the two most common human polyomaviruses (HPyVs). These two viruses inhabit the epithelial surfaces of the bladder and kidney as the primary site of replication and latency.
Kawther A. AlMalaki, Asmaa' B. Al-Obaidi, Haider F. Ghazi   +2 more
doaj   +3 more sources

Polyomavirus infections and its clinical relevance in cancer patients: A Prospective Study

Journal of Infection and Public Health, 2017
Summary: BK and JC polyomaviruses (PyV) have been demonstrated to be associated with the pathogenesis of various human cancers. We aimed to investigate the impact of BK and JC polyomavirus infections on several clinical parameters in different human ...
Samah A. Loutfy, Manar M. Moneer, Salem E. Salem, Emad A. El-Moniem Abada, Entsar A. El-Moniem Ahmed, Lamiaa H. Ibrahim, EL-Chaimaa B. Mohamed   +6 more
doaj   +1 more source

Comparison of two RT-qPCR methods targeting BK polyomavirus microRNAs in kidney transplant recipients

Frontiers in Medicine, 2023
BackgroundBK polyomavirus replication leads to progressive tubulointerstitial nephritis and ureteral stenosis, with a considerable risk of subsequent graft failure in kidney transplant recipients. Since specific antiviral therapies are lacking, new tools
Kenza Zoubir, Kenza Zoubir, Véronique Descamps, Véronique Descamps, Aurélien Aubry, Aurélien Aubry, Francois Helle, Catherine Francois, Catherine Francois, Sandrine Castelain, Sandrine Castelain, Etienne Brochot, Etienne Brochot, Baptiste Demey, Baptiste Demey   +14 more
doaj   +1 more source

Molecular Evaluation of BK Polyomavirus Nephropathy

American Journal of Transplantation, 2005
Understanding at a molecular level, the immunologic response of polyomavirus nephropathy (PVN), a critical cause of kidney graft loss, could lead to new targets for treatment and diagnosis. We undertook a transcriptional evaluation of kidney allograft biopsies from recipients with PVN or acute rejection (AR), as well as from recipients with stable ...
R B, Mannon, S C, Hoffmann, R L, Kampen, O C, Cheng, D E, Kleiner, C, Ryschkewitsch, B, Curfman, E, Major, D A, Hale, A D, Kirk   +9 more
openaire   +2 more sources

Association of donor hepatitis C virus infection status and risk of BK polyomavirus viremia after kidney transplantation

American Journal of Transplantation, 2021
Kidney transplantation (KT) from deceased donors with hepatitis C virus (HCV) into HCV‐negative recipients has become more common. However, the risk of complications such as BK polyomavirus (BKPyV) remains unknown.
M. Z. Molnar, Vishnu S. Potluri, D. Schaubel, M. Sise, B. Concepcion, R. Forbes, E. Blumberg, R. Bloom, D. Shaffer, R. Chung, I. Strohbehn, N. Elias, Ambreen Azhar, Mital Shah, D. Sawinski, Laura A. Binari, M. Talwar, V. Balaraman, Anshul Bhalla, J. Eason, B. Besharatian, J. Trofe‐Clark, D. Goldberg, P. Reese   +23 more
semanticscholar   +1 more source

Fluoroquinolone prophylaxis in preventing BK polyomavirus infection after renal transplant: A systematic review and meta-analysis

Kaohsiung Journal of Medical Sciences, 2016
Previous studies regarding the prevention of BK viremia following renal transplantation with fluoroquinolone have yielded conflicting results. The purpose of this systematic review was to examine the evidence regarding the efficacy of fluoroquinolone in ...
Tu-Run Song, Zheng-Sheng Rao, Yang Qiu, Jin-Peng Liu, Zhong-Li Huang, Xian-Ding Wang, Tao Lin   +6 more
doaj   +1 more source