Results 51 to 60 of about 61,588 (194)
Indian Journal of Transplantation, 2022 Purpose: Hemorrhagic cystitis (HC) which occurs in 9%–31% of recipients after hematopoietic stem cell transplantation (HSCT) is an important cause of morbidity and mortality.
Ayça Koca Yozgat +7 more
doaj +1 more source
Detection of Bk Polyomavirus Antigen in Patients with Acute Lymphoblastic Leukemia
Diyala Journal of Medicine, 2023 Background: BK polyomavirus that is acquired in early childhood as BKPyV is near ubiquitous in adults with a seroprevalence of >80%, it has been found as the main cause of hemorrhagic cystitis in hematopoietic stem cell transplantation patients, due to
Safa H Ali , +3 more
doaj +1 more source
BK Virus in Cancer Development
Current Issues in Pharmacy and Medical Sciences, 2018 Polyomavirus (PyV) was discovered by accident in 1950 in the course of describing an infectious factor causing multiple tumours in rodents. The term is derived from two Greek words: poly (many) and oma (tumour).
Pasternak Justyna +2 more
doaj +1 more source
TransplantationBK polyomavirus (BKPyV) remains a significant challenge after kidney transplantation. International experts reviewed current evidence and updated recommendations according to Grading of Recommendations, Assessment, Development, and Evaluations (GRADE ...
C. Kotton +16 more
semanticscholar +1 more source
BK polyomavirus—pathogen, paradigm and puzzle
Nephrology Dialysis Transplantation, 2019 AbstractBK virus is a polyomavirus with seroprevalence rates of 80% in adults. Infection is usually acquired during childhood, and the virus is benign or pathologic depending on immune status. The virus reactivates in immunodeficiency states, mostly among transplant (either kidney or bone marrow) recipients.
Suman Krishna Kotla +3 more
openaire +2 more sources
Evaluation of polyomavirus BK reactivation in lupus patients who underwent kidney transplantation
Microbiologia Medica, 2012 Background. A pathogenic role for polyomavirus BK in systemic lupus erythematosus (SLE) has been proposed, however no study evaluated the occurrence of BK replication in renal transplant recipients according to the underlying disease leading to ...
Cristina Costa +9 more
doaj +1 more source
Taking the Scenic Route: Polyomaviruses Utilize Multiple Pathways to Reach the Same Destination
Viruses, 2020 Members of the Polyomaviridae family differ in their host range, pathogenesis, and disease severity. To date, some of the most studied polyomaviruses include human JC, BK, and Merkel cell polyomavirus and non-human subspecies murine and simian virus 40 ...
Colleen L. Mayberry, Melissa S. Maginnis
doaj +1 more source
Control of Archetype BK Polyomavirus MicroRNA Expression
Journal of Virology, 2020 The BK polyomavirus (BKPyV) miRNA plays an important role in regulating viral large-T-antigen expression and limiting the replication of archetype BKPyV, suggesting that the miRNA regulates BKPyV persistence. However, how miRNA expression is regulated is poorly understood.
Wei Zou +5 more
openaire +3 more sources
Transplant Infectious Disease, EarlyView.Third‐party, BK virus‐specific cytotoxic T lymphocytes (CTLs) were safe and effective in reducing viremia in kidney and stem cell transplant recipients with BK virus nephropathy. However, they did not improve kidney function. Earlier administration may be more beneficial before nephropathy and irreversible damage occur.
Amanda Olson +18 more
wiley +1 more source
Transplant Infectious DiseaseBK polyomavirus‐associated nephropathy (BKPyVAN) is an important cause of allograft dysfunction and failure in kidney transplant recipients (KTRs) and there are no proven effective treatments. Case reports and in vitro data support the potential activity
Hannah Imlay +11 more
semanticscholar +1 more source