Results 61 to 70 of about 2,195 (192)

The risk factors associated with post-transplantation BKPyV nephropathy and BKPyV DNAemia: a prospective study in kidney transplant recipients

BMC Infectious Diseases
Abstract Background BK polyomavirus (BKPyV) infection after kidney transplantation can lead to serious complications such as BKPyV-associated nephropathy (BKPyVAN) and graft loss. The aim of this study was to investigate the incidence of BKPyVAN after implementing a BKPyV screening program, to map the distribution of ...
Lorant, Camilla, Zigmantaviciute, Justina, Ali, Naima, Bonnevier, Ursa, Tejde, Mattias, von Zur-Mühlen, Bengt, Eriksson, Britt-Marie, Bergqvist, Anders, Westman, Gabriel   +8 more
openaire   +4 more sources

Pre-Transplantation Assessment of BK Virus Serostatus: Significance, Current Methods, and Obstacles

Viruses, 2019
The immunosuppression required for graft tolerance in kidney transplant patients can trigger latent BK polyomavirus (BKPyV) reactivation, and the infection can progress to nephropathy and graft rejection.
Fatima Dakroub, Antoine Touzé, Haidar Akl, Etienne Brochot   +3 more
doaj   +1 more source

The PP4R1 sub-unit of protein phosphatase PP4 is essential for inhibition of NF-kB by Merkel Polyomavirus small Tumour antigen [PDF]

, 2017
Merkel cell carcinoma (MCC) is a highly aggressive skin cancer with a high metastatic potential. The majority of MCC cases are caused by the Merkel cell polyomavirus (MCPyV), through expression of the virus-encoded tumour antigens.
Agou, Akira, Becker, Bossuyt, Bowie, Chang, Chen, Cohen, Cohen, DeCaprio, Dikic, Dikic, Fischer, Garcea, Harris, Harris, Hatzivassiliou, Hesbacher, Israël, Jain, Klemke, Macdonald, Macdonald, Macdonald, Macdonald, Macdonald, Macdonald, Marshall, McFadden, McFadden, Moore, Moore, Moore, Perkins, Qi, Roberts, Scott, Senechal, Wadzinski, Whitehouse, Whitehouse, Whitehouse, Wu   +42 more
core   +3 more sources

BK Polyomavirus in Pediatric Renal Transplantation—What We Know and What We Do Not

Biomedicines
BK polyomavirus (BKPyV) is still a real threat in the management of kidney transplantation. Immunosuppressive treatment disrupts the equilibrium between virus replication and immune response, and uncontrolled BKPyV replication leads to nephropathy (BKPyV
Benedetta Chiodini, Pauline Guillaume-Gentil, Charlotte Vanhomwegen, Elise Hennaut, Ksenija Lolin, Nathalie Tram, Alain Le Moine, Khalid Ismaili   +7 more
doaj   +1 more source

Early fulminant BK polyomavirus-associated nephropathy in two kidney transplant patients with low neutralizing antibody titers receiving allografts from the same donor

Virology Journal, 2020
Background BK Polyomavirus (BKPyV) causes premature graft failure in 1 to 15% of kidney transplant (KT) recipients. High-level BKPyV-viruria and BKPyV-DNAemia precede polyomavirus-associated nephropathy (PyVAN), and guide clinical management decisions ...
Elias Myrvoll Lorentzen, Stian Henriksen, Amandeep Kaur, Grete Birkeland Kro, Clara Hammarström, Hans H. Hirsch, Karsten Midtvedt, Christine Hanssen Rinaldo   +7 more
doaj   +1 more source

Merkel cell polyomavirus: molecular insights into the most recently discovered human tumour virus. [PDF]

, 2014
A fifth of worldwide cancer cases have an infectious origin, with viral infection being the foremost. One such cancer is Merkel cell carcinoma (MCC), a rare but aggressive skin malignancy.
Abdul-Sada, H, Adzahar, NS, Knight, LM, Macdonald, A, Nwogu, N, Stakaitytė, G, Whitehouse, A, Wood, JJ   +7 more
core   +3 more sources

Next-generation sequencing shows marked rearrangements of BK polyomavirus that favor but are not required for polyomavirus-associated nephropathy [PDF]

, 2020
Background BKPyV is associated with polyomavirus-associated nephropathy (PVAN), a major cause of graft rejection in kidney transplant recipients (KTRs).
Aberle, Stephan W., Auvinen, Eeva, Bond, Gregor, Liimatainen, Hanna, Strassl, Robert, Weseslindtner, Lukas   +5 more
core   +1 more source

DNA Virus Detection in Olfactory Neuroblastomas Using Targeted Enrichment NGS

Neuropathology, Volume 46, Issue 2, April 2026.
ABSTRACT A variety of malignancies can be found in the sinonasal tract including the nasal cavity, paranasal sinuses, and skull base. Many of these are attributed to viruses, for example, carcinomas with the presence of transcriptionally active high‐risk human papillomavirus, as well as Epstein–Barr virus associated malignant lymphoepithelial carcinoma
Maria K. Jauhiainen, Outi I. Mielonen, Aaro Haapaniemi, Maria Söderlund‐Venermo, Jaana Hagström, Maria F. Perdomo, Saku T. Sinkkonen, Antti A. Mäkitie   +7 more
wiley   +1 more source

Polyomaviruses in blood donors:Detection, prevalence and blood safety [PDF]

, 2022
Polyomaviruses are a family of viruses with a small genome, wrapped in a viral particle with a diameter of 40-45 nanometres. Polyomaviruses are able to persist in the human body. This means that a person, once infected, does not lose the virus despite an
Kamminga, S.
core   +4 more sources

Anion homeostasis is important for non-lytic release of BK polyomavirus from infected cells [PDF]

Open Biology, 2015
BK polyomavirus (BKPyV) is a member of a family of potentially oncogenic viruses, whose reactivation can cause severe pathological conditions in transplant patients, leading to graft rejection. As with many non-enveloped viruses, it is assumed that virus
Gareth L. Evans, Laura G. Caller, Victoria Foster, Colin M. Crump   +3 more
doaj   +1 more source