Results 171 to 180 of about 577,492 (298)

A post hoc analysis of linaclotide in pediatric patients with functional constipation and neurodevelopmental disorders

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Functional constipation (FC) is common in children with comorbid neurodevelopmental disorders (NDD) and its optimal treatment may be challenged by adherence and medication tolerability issues in this population. We assessed the efficacy and safety of linaclotide in pediatric patients with FC and NDD.
Hannibal Person   +9 more
wiley   +1 more source

Effects of catechins, resveratrol, silymarin components and some of their conjugates on xanthine oxidase‐catalyzed xanthine and 6‐mercaptopurine oxidation

open access: yesJournal of the Science of Food and Agriculture, Volume 105, Issue 5, Page 2765-2776, 30 March 2025.
Abstract BACKGROUND Over the past two decades, the global incidence of gout has markedly increased, affecting people worldwide. Considering the side effects of xanthine oxidase (XO) inhibitor drugs (e.g. allopurinol and febuxostat) used in the treatment of hyperuricemia and gout, the potential application of phytochemicals has been widely studied.
Tímea Bencsik   +6 more
wiley   +1 more source

Nutritional characterization of Cusco green tea and its synergistic effect with omega‐3 on metabolic and cognitive dysfunctions in obese rats

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Obesity and its metabolic complications, such as insulin resistance and cognitive decline, remain a global health challenge. Green tea (Camelia sinensis) and ω‐3 polyunsaturated fatty acids (PUFAs) are recognized for their antioxidant, anti‐inflammatory, and neuroprotective properties.
Paola Finetti‐Casanova   +5 more
wiley   +1 more source

Community awareness of association between black tea consumption and iron deficiency anemia. [PDF]

open access: yesJ Family Med Prim Care
Alorainy M   +6 more
europepmc   +1 more source

Latex Serum‐Derived Supramolecular Networks Enable Toughening of Natural Rubber

open access: yesMacromolecular Rapid Communications, EarlyView.
Latex‐serum addition enhances strain‐induced crystallization (SIC) toughening in natural rubber, increasing tearing strength and extending the SIC activation window. Supramolecular networks form via bifurcated hydrogen bonding between polyol components (e.g., quebrachitol) and end‐functionalized polyisoprene chains, serving as effective crystallization
Katsuhiko Tsunoda   +5 more
wiley   +1 more source

A Non‐Antigenic Randomized Polyethylene Glycol/Poly(2‐Phenyl‐2‐Oxazine)‐Based Drug Delivery Platform

open access: yesMacromolecular Rapid Communications, EarlyView.
Randomized PEG (rPEG), a conceptually new PEG alternative, is combined with poly(2‐phenyl‐2‐oxazine) (PPheOzi) to establish an rPEG‐b‐PPheOzi‐b‐rPEG micellar drug delivery platform. The PPheOzi block enables high drug loadings, while competitive ELISA reveals a drastic reduction in anti‐PEG antibody affinity of rPEG in comparison to PEG.
Julian Schmidt   +6 more
wiley   +1 more source

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