Results 1 to 10 of about 15,201 (184)

Development of a prognostic model related to mitochondria and programmed cell death-related genes in bladder cancer [PDF]

open access: yesFrontiers in Genetics
BackgroundVarious forms of programmed cell death (PCD) play a crucial role in regulating the development and spread of cancer, with mitochondria serving as key organelles involved in executing PCD.
Xuwei Zhao   +8 more
doaj   +2 more sources

MFSD12, transcriptionally regulated by PLAGL2, promotes bladder cancer progression [PDF]

open access: yesCommunications Biology
Bladder cancer (BLCA) is one of the most common malignant tumors of the urinary system. Identification of novel molecular signaling targets for the tumorigenesis of BLCA is important.
Jiani He   +8 more
doaj   +2 more sources

Metabolic changes preceding bladder cancer occurrence among Korean men: a nested case-control study from the KCPS-II cohort

open access: yesCancer & Metabolism, 2023
Background Bladder cancer (BLCA) research in Koreans is still lacking, especially in focusing on the prediction of BLCA. The current study aimed to discover metabolic signatures related to BLCA onset and confirm its potential as a biomarker.
Youngmin Han   +7 more
doaj   +1 more source

Clinical significance and potential regulatory mechanism of overexpression of pituitary tumor-transforming gene transcription factor in bladder cancer

open access: yesBMC Cancer, 2022
Background Pituitary tumor transforming gene-1 (PTTG1) transcription factor is identified as carcinogenic and associated with tumor invasiveness, but its role in bladder cancer (BLCA) remains obscure.
Jian-Di Li   +10 more
doaj   +1 more source

Values of OAS gene family in the expression signature, immune cell infiltration and prognosis of human bladder cancer

open access: yesBMC Cancer, 2022
Background Bladder cancer (BLCA) is one of the most common genitourinary malignancies in the world, but its pathogenic genes have not been fully identified and the treatment outcomes are still unsatisfactory. Although the members of 2', 5'-oligoadenylate
Lijuan Gao   +11 more
doaj   +1 more source

SIRT4 is an independent prognostic factor in bladder cancer and inhibits bladder cancer growth by suppressing autophagy

open access: yesCell Division, 2023
Background Nucleosome-localized sirtuin 4 (SIRT4) was found to function as an oncogene and tumor suppressor gene in different tumors. However, the clinical significance of SIRT4 in bladder urothelial carcinoma (BLCA) has not been assessed, nor has the ...
Jie Yin   +5 more
doaj   +1 more source

AIM2 inflammasome activation benefits the therapeutic effect of BCG in bladder carcinoma

open access: yesFrontiers in Pharmacology, 2022
A large proportion of bladder cancer (BLCA) patients suffer from malignant progression to life-threatening muscle-invasive bladder cancer (MIBC). Inflammation is a critical event in cancer development, but little is known about the role of inflammation ...
Houhong Zhou   +10 more
doaj   +1 more source

Annexin A1 promotes the progression of bladder cancer via regulating EGFR signaling pathway

open access: yesCancer Cell International, 2022
Background Bladder cancer (BLCA) is one of the most common malignancies worldwide. One of the main reasons for the unsatisfactory management of BLCA is the complex molecular biological mechanism.
Piao Li   +10 more
doaj   +1 more source

NUPR1 imparts oncogenic potential in bladder cancer

open access: yesCancer Medicine, 2023
Background NUPR1, or p8, is a small chromatin protein that plays a central role in the resistance to treatment and progression of cancer. Nevertheless, the molecular mechanism of NUPR1 in bladder cancer (BLCA) remains unclear.
Lifeng Zhang   +7 more
doaj   +1 more source

Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas [PDF]

open access: yes, 2018
This integrated, multiplatform PanCancer Atlas study co-mapped and identified distinguishing molecular features of squamous cell carcinomas (SCCs) from five sites associated with ...
Abdel-Rahman, Mohamed H.   +784 more
core   +6 more sources

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