Results 91 to 100 of about 12,929 (204)

Pathway-based cancer transcriptome deciphers a high-resolution intrinsic heterogeneity within bladder cancer classification

Journal of Translational Medicine
Background The heterogeneity of bladder cancer (BLCA) is affected by its inherent transcriptional properties and tumor microenvironment (TME). Stromal transcriptional components in the TME significantly influence the transcriptional classification of ...
Zhan Wang, Zhaokai Zhou, Shuai Yang, Zhengrui Li, Run Shi, Ruizhi Wang, Kui Liu, Xiaojuan Tang, Qi Li   +8 more
doaj   +1 more source

α-E-Catenin (CTNNA1) Inhibits Cell Proliferation, Invasion and EMT of Bladder Cancer

Cancer Management and Research, 2020
Qiang Chi, Hui Xu, Dianbin Song, Zhiyong Wang, Zemin Wang, Guang Ma Department of Urology, Affiliated Hospital of Chengde Medical University, Chengde 067000, People’s Republic of ChinaCorrespondence: Qiang ChiDepartment of Urology, Affiliated ...
Chi Q, Xu H, Song D, Wang Z, Wang Z, Ma G   +5 more
doaj  

A molecular landscape and prognosis signature based on histone tyrosine sulfation in pan‐cancer analysis

Clinical and Translational Discovery, Volume 6, Issue 4, August 2026.
A pan‐cancer transcriptional signature based on histone tyrosine sulfation (HYsulf) reveals associations with immune infiltration, metabolic reprogramming and patient prognosis, thereby enabling the development of predictive nomograms for PCPG and UVM.
Meijuan Cai, Yuhao Liao, Jun Lin, Xumeng Chen, Jiale Wang, Zhijuan Li, Zhengjun Yang, DianKui Cai   +7 more
wiley   +1 more source

FOXA1 is a highly sensitive diagnostic marker for prostate cancer including small cell carcinoma of the prostate

Histopathology, Volume 89, Issue 2, Page 240-250, August 2026.
FOXA1 is a highly sensitive diagnostic marker for prostate cancer. Besides prostatic adenocarcinoma, it is also expressed in 57%–80% of metastatic or primary prostatic small cell carcinomas, which lose traditional prostatic markers including NKX3.1. Although it is less specific than NKX3.1, it can serve as a valuable adjunct for confirming prostatic ...
Jianping Zhao, Jun Yao, Hossein Hosseini, Ezra Baraban, Ruihe Lin, Charles C. Guo, Lei Huo, Wei Lu, Khaja Khan, Shufang Wang, Luisa Maren Solis Soto, Qingqing Ding   +11 more
wiley   +1 more source

Implementasi Blended Learning by the Constructive Approach (BLCA) untuk Meningkatkan Pemahaman Konsep dan Kemandirian Belajar Mahasiswa dalam Matakuliah Interaksi Manusia dan Komputer Prodi Teknologi Pendidikan FIP UNY [PDF]

, 2013
Penelitian ini bertujuan untuk: 1) mengetahui implementasi blended learning by the constructive approach (BLCA) dalam matakuliah Interaksi Manusia dan Komputer (IMK) Prodi Teknologi Pendidikan (TP) FIP UNY; 2) meningkatkan pemahaman konsep mahasiswa ...
Wahyuningsih, dian
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CXCL10 could be a prognostic and immunological biomarker in bladder cancer

Discover Oncology
Introduction As proteins that promote immune cell differentiation, chemokines have attracted great interest regarding their role in anti-tumor immune responses within the cancer environment.
Tao Yin, Shuanzhu Mou, Haiyu Zhang, Ying Dong, Bing Yan, Weisheng Huang, Yuhan Liu, Hongbing Mei   +7 more
doaj   +1 more source

Tumor‐Intrinsic ARHGEF3 Enhances Antitumor Immunity by Promoting T‐Cell Infiltration and Limiting Myeloid Cell‐Mediated Immunosuppression

Advanced Science, Volume 13, Issue 38, 9 July 2026.
ARHGEF3 is broadly downregulated across human cancers and correlates with patient prognosis. Tumor‐intrinsic ARHGEF3 activates the RHOA–ROCK–PTEN cascade to inhibit AKT signaling, thereby promoting chemokine‐driven T‐cell infiltration and relieving lipid‐mediated myeloid immunosuppression.
Yue Li, Lan Wang, Zihao Zhang, Chunmei Qian, Ning Li, Wei Huang, Qian Ba, Xiaojian Liu, Mayu Sun   +8 more
wiley   +1 more source

Comparing urine levels of BLCA-4 nuclear matrix protein in patients with bladder cancer and non-bladder cancer [PDF]

, 2019
BACKGROUND: The molecular mechanism of bladder cancer is yet not fully understood. Aim of this study was to compare the levels of BLCA-4 nuclear matrix protein in the urine of patients with bladder cancer and non-affected individuals.
Izadpanahi, Mohammad-Hosein, Faridizad, Romina, Haghshenas, L., Ghadimi, Keyvan, Eslami, Mohammad-Javad, Alavi, Ali   +5 more
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Pan‐cancer atlas of cellular architecture reveals a nearest‐neighbour distance‐associated biomechanical‐immune axis involving CD4+ memory T cells

Clinical and Translational Medicine, Volume 16, Issue 7, July 2026.
1. NND extracted from routine H&E slides serves as a spatial proxy for mechanical crowding across 21 cancer types. 2. Low NND is associated with Hippo/YAP/TAZ pathway activation and CD4+ TMem cell enrichment, validated by single‐cell and spatial transcriptomics. 3.
Linglong Huang, Arne Östman, Yunfan Sun
wiley   +1 more source

膀胱癌新型标志物BLCA-4蛋白的研究进展 [PDF]

, 2007
膀胱癌是常见的恶性肿瘤之一,复发率高。传统的诊断方法多有创伤性,检删方法敏感性和特异性不高。随着分子生物学发展,近年来发现了6种新的膀胱癌特异性核基质蛋白,其中尿液BLCA-4蛋白对膀胱癌早期诊断具有较好的临床应用前景,现就BLCA-4蛋白研究现状进行综述。厦门市卫生局2004年度医学科研立项(厦卫科教中医2004-400号)
张忠英, 陈亮, 刘莉莉
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