Results 81 to 90 of about 15,721 (211)

Implementasi Blended Learning by the Constructive Approach (BLCA) untuk Meningkatkan Pemahaman Konsep dan Kemandirian Belajar Mahasiswa dalam Matakuliah Interaksi Manusia dan Komputer Prodi Teknologi Pendidikan FIP UNY [PDF]

, 2013
Penelitian ini bertujuan untuk: 1) mengetahui implementasi blended learning by the constructive approach (BLCA) dalam matakuliah Interaksi Manusia dan Komputer (IMK) Prodi Teknologi Pendidikan (TP) FIP UNY; 2) meningkatkan pemahaman konsep mahasiswa ...
Wahyuningsih, dian
core  

Knowledge about the presence or absence of miRNA isoforms (isomiRs) can successfully discriminate amongst 32 TCGA cancer types. [PDF]

, 2017
Isoforms of human miRNAs (isomiRs) are constitutively expressed with tissue- and disease-subtype-dependencies. We studied 10 271 tumor datasets from The Cancer Genome Atlas (TCGA) to evaluate whether isomiRs can distinguish amongst 32 TCGA cancers ...
Chervoneva, Inna, Loher, Phillipe, Londin, Eric, Magee, Rogan, Rigoutsos, Isidore, Telonis, Aristeidis G.   +5 more
core   +2 more sources

α-E-Catenin (CTNNA1) Inhibits Cell Proliferation, Invasion and EMT of Bladder Cancer

Cancer Management and Research, 2020
Qiang Chi, Hui Xu, Dianbin Song, Zhiyong Wang, Zemin Wang, Guang Ma Department of Urology, Affiliated Hospital of Chengde Medical University, Chengde 067000, People’s Republic of ChinaCorrespondence: Qiang ChiDepartment of Urology, Affiliated ...
Chi Q, Xu H, Song D, Wang Z, Wang Z, Ma G   +5 more
doaj  

Absence of an embryonic stem cell DNA methylation signature in human cancer. [PDF]

, 2019
BackgroundDifferentiated cells that arise from stem cells in early development contain DNA methylation features that provide a memory trace of their fetal cell origin (FCO). The FCO signature was developed to estimate the proportion of cells in a mixture
Christensen, Brock C, Kelsey, Karl T, Koestler, Devin C, Salas, Lucas A, Wiencke, John K, Zhang, Ze   +5 more
core  

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, Volume 20, Issue 5, Page 1299-1322, May 2026.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Solving problems of clustering and classification of cancer diseases based on DNA methylation data [PDF]

, 2016
The article deals with the problem of diagnosis of oncological diseases based on the analysis of DNA methylation data using algorithms of cluster analysis and supervised learning.
Druzhkov, PN, Ivanchenko, MV, Krylov, IB, Meyerov, IB, Polovinkin, AN, Zaikin, AA, Zolotykh, NY   +6 more
core   +1 more source

Pancancer Fine‐Mapping of Mutational Intolerance Identifies CHEK1 as an Immunosuppressive Driver in Lung Adenocarcinoma

Advanced Science, Volume 13, Issue 25, 4 May 2026.
This study identifies mutation‐intolerant genes (MIGs), which are mutationally constrained in tumors despite normal‐tissue variability. Using miDriver, the authors pinpoint MIGs essential for tumor‐intrinsic fitness and immune evasion. Focusing on CHEK1, they show it drives tumor fitness and sculpts an immunosuppressive niche via the MIF–CD74 axis ...
Tao Wang, Hongyu Zhao, Xiaojie Sun, Yuqi Ding, Zhipeng Zhu, Xiaotong Yu, Rongyi Zhu, Dan Wang, Kailong Li, Yang Liu, Li‐Bin Wang, Xiaolu Zhao, Baojun Suo, Hongsen Bi, Peipei Zhang, Tong Liu, Fengbiao Mao   +16 more
wiley   +1 more source

A Multi-Method Approach for Proteomic Network Inference in 11 Human Cancers. [PDF]

, 2016
Protein expression and post-translational modification levels are tightly regulated in neoplastic cells to maintain cellular processes known as 'cancer hallmarks'.
Bemis, D., Ciriello, G., Sander, C., Schultz, N., Sánchez-Vega, F., Sümer, S.O., Şenbabaoğlu, Y.   +6 more
core   +3 more sources

CXCL10 could be a prognostic and immunological biomarker in bladder cancer

Discover Oncology
Introduction As proteins that promote immune cell differentiation, chemokines have attracted great interest regarding their role in anti-tumor immune responses within the cancer environment.
Tao Yin, Shuanzhu Mou, Haiyu Zhang, Ying Dong, Bing Yan, Weisheng Huang, Yuhan Liu, Hongbing Mei   +7 more
doaj   +1 more source

Tumor‐Derived Exosomal TAGLN2 Promotes Metastasis by Inducing Vascular Permeability and Angiogenesis via the NRP1/SEMA4D/YAP Axis

Advanced Science, Volume 13, Issue 29, 22 May 2026.
Gastric cancer‐derived exosomal TAGLN2 is identified as a key mediator of vascular reprogramming, with significantly elevated levels detected in patient serum. Independent of canonical SEMA4D signaling, it nucleates a cytoplasmic TAGLN2/NRP1/SEMA4D ternary complex that dually activates YAP, promoting angiogenesis, vascular dysfunction, and metastasis ...
Shuqi Yu, Jiajia Zhuo, Xiaoquan Hong, Shihao Rao, Yafang Ye, Dandan Kang, Huifang Peng, Huiqin Zhuo   +7 more
wiley   +1 more source