Results 71 to 80 of about 15,721 (211)

CDCOCA: A statistical method to define complexity dependence of co-occuring chromosomal aberrations [PDF]

, 2011
Background Copy number alterations (CNA) play a key role in cancer development and progression. Since more than one CNA can be detected in most tumors, frequently co-occurring genetic CNA may point to cooperating cancer related genes.
Baudis, Michael, Cai, H, Kumar, N, Rehrauer, H   +3 more
core   +1 more source

Prediction of Prognosis and Recurrence of Bladder Cancer by ECM-Related Genes

Journal of Immunology Research, 2022
Background. Bladder cancer (BLCA) is one of the most common cancers and ranks ninth among all cancers. Extracellular matrix (ECM) genes activate a number of pathways that facilitate tumor development.
Hongfan Zhao, Zihao Chen, Yunze Fang, Mingqiang Su, Yipeng Xu, Zhifeng Wang, Michael Adu Gyamfi, Junfeng Zhao   +7 more
doaj   +1 more source

FOXA1 is a highly sensitive diagnostic marker for prostate cancer including small cell carcinoma of the prostate

Histopathology, EarlyView.
FOXA1 is a highly sensitive diagnostic marker for prostate cancer. Besides prostatic adenocarcinoma, it is also expressed in 57%–80% of metastatic or primary prostatic small cell carcinomas, which lose traditional prostatic markers including NKX3.1. Although it is less specific than NKX3.1, it can serve as a valuable adjunct for confirming prostatic ...
Jianping Zhao, Jun Yao, Hossein Hosseini, Ezra Baraban, Ruihe Lin, Charles C. Guo, Lei Huo, Wei Lu, Khaja Khan, Shufang Wang, Luisa Maren Solis Soto, Qingqing Ding   +11 more
wiley   +1 more source

INTEGRATIVE ANALYSIS OF OMICS DATA IN ADULT GLIOMA AND OTHER TCGA CANCERS TO GUIDE PRECISION MEDICINE [PDF]

, 2017
Transcriptomic profiling and gene expression signatures have been widely applied as effective approaches for enhancing the molecular classification, diagnosis, prognosis or prediction of therapeutic response towards personalized therapy for cancer ...
hu, Xin, hu, xin
core   +1 more source

Mitochondrial DNA copy number variation across human cancers. [PDF]

, 2016
Mutations, deletions, and changes in copy number of mitochondrial DNA (mtDNA), are observed throughout cancers. Here, we survey mtDNA copy number variation across 22 tumor types profiled by The Cancer Genome Atlas project.
Al-Ahmadie, Hikmat A, Hakimi, A Ari, Lee, William, Miller, Martin L, Reznik, Ed, Riaz, Nadeem, Sander, Chris, Sarungbam, Judy, Seshan, Venkatraman E, Tickoo, Satish K, Şenbabaoğlu, Yasin   +10 more
core   +1 more source

Construction and evaluation of a bladder cancer prognosis model based on super-enhancer-associated genes

Discover Oncology
Introduction Bladder cancer (BLCA) is a malignant tumour that occurs on the mucosa of the bladder. It accounts for the first place in the incidence of genitourinary tumours in China.
Lieyu Xu, Zhenhao Zeng, Xinchang Zou, Zunwei Zhu, Tao Zeng   +4 more
doaj   +1 more source

Cancer heterogeneity explored through immune cell deconvolution of the tumor microenvironment

Quantitative Biology, Volume 14, Issue 3, September 2026.
Abstract Cancer is a highly heterogeneous disease, characterized by significant variability across multiple dimensions. This diversity has been extensively studied from various perspectives. In this study, we aim to examine cancer heterogeneity through the lens of immune cell composition within the tumor microenvironment.
Limin Jiang, Chung‐I Li, Rui Xin, Jijun Tang, Yan Guo   +4 more
wiley   +1 more source

A metabolic reprogramming-related gene signature correlates with prognosis and proliferation of BLCA

Discover Oncology
Bladder cancer (BLCA) is one of the most frequent urothelium carcinoma, but with poor prognosis due to lack of reliable predictive biomarkers. Metabolic reprogramming involving in various nutrients, and is reported to be closely associated with malignant progression in BLCA.
Yaoxin Wu, Yi Luo, Tinghao Li
openaire   +3 more sources

Pathway-based cancer transcriptome deciphers a high-resolution intrinsic heterogeneity within bladder cancer classification

Journal of Translational Medicine
Background The heterogeneity of bladder cancer (BLCA) is affected by its inherent transcriptional properties and tumor microenvironment (TME). Stromal transcriptional components in the TME significantly influence the transcriptional classification of ...
Zhan Wang, Zhaokai Zhou, Shuai Yang, Zhengrui Li, Run Shi, Ruizhi Wang, Kui Liu, Xiaojuan Tang, Qi Li   +8 more
doaj   +1 more source

On why cancer cells require a great amount of glucose

Quantitative Biology, Volume 14, Issue 2, June 2026.
Abstract The traditional thinking has been that cancer cells require a great amount of glucose to support their rapid growth, but the reality may be different. We have previously demonstrated that all cancer cells in The Cancer Genome Atlas harbor persistent Fenton reactions in their cytosol, which generate OH− ${\text{OH}}^{-}$ and ultimately kill the
Xuechen Mu, Aoran Liu, Rui Shi, Long Xu, Zhenyu Huang, Ye Zhang, Ying Xu   +6 more
wiley   +1 more source