Results 71 to 80 of about 12,929 (204)

The correlation between SCD expression and immune cells infiltration levels in BLCA、CESC、KICH and LGG. [PDF]

open access: yes
(A) The expression level of SCD was significantly correlated with infiltrating levels of different immune cells in BLCA、CESC and LGG. (TIF)
Jiang Jiang (1513975)   +4 more
core   +1 more source

Supplementary Figure S8 from Multi-omics Integration Analysis Robustly Predicts High-Grade Patient Survival and Identifies CPT1B Effect on Fatty Acid Metabolism in Bladder Cancer [PDF]

open access: yes, 2019
Supplementary Figure S8. A) FAO activity in BLCA cell lines upon CPTB overexpression. B) mRNA expression of ATP8B2 and PLA2G4C in patients with BLCA and BLCA cell lines of different grades. mRNA levels were normalized to GAPDH internal control.
Chandrashekar R. Ambati (15011102)   +24 more
core   +1 more source

A cancer-associated fibroblast subtypes-based signature enables the evaluation of immunotherapy response and prognosis in bladder cancer [PDF]

open access: yes, 2023
Summary: Bladder cancer (BLCA) is one of the most prevalent and heterogeneous urinary malignant tumors. Previous researches have reported a significant association between cancer-associated fibroblasts (CAFs) and poor prognosis of tumor patients. However,
Hong Shen   +16 more
core   +1 more source

TEAD4 functions as a prognostic biomarker and triggers EMT via PI3K/AKT pathway in bladder cancer

open access: yesJournal of Experimental & Clinical Cancer Research, 2022
Background The distant metastasis is the primary cause of cancer morbidity and mortality for bladder cancer (BLCA) paitents. All the recommended therapy for it largely depends on how far the cancer has invaded.
Ming Chi   +13 more
doaj   +1 more source

O‐GlcNAcylation of KAT2A Enhances Bladder Cancer Proliferation by Inhibiting the KAT2A‐TRIM22 Interaction

open access: yesCancer Science, EarlyView.
Lysine acetyltransferase 2A (KAT2A) is a transcriptional coactivator and a member of the Histone Acetyltransferase (HAT) family. While altered KAT2A activity has been implicated in various cancers, its role in bladder cancer (BLCA) remains poorly understood.
Wenjie Yang   +8 more
wiley   +1 more source

UBE2C‐Mediated CD147‐CTLA‐4 Axis Promotes T Cell Exhaustion and Immunosuppressive Microenvironment in Bladder Cancer

open access: yesCancer Science, EarlyView.
UBE2C upregulates cellular CD147 and enhances its release into the tumor microenvironment both as soluble CD147 (sCD147) and packaged within tumor‐derived exosomes. These CD147‐bearing signals induce T‐cell exhaustion, marked by elevated CTLA‐4 expression and reduced secretion of effector cytokines (IFN‐γ, TNF‐α, TGF‐β), ultimately diminishing CD8+ T ...
Xuwei Hong   +7 more
wiley   +1 more source

PARP inhibitors chemopotentiate and synergize with cisplatin to inhibit bladder cancer cell survival and tumor growth

open access: yesBMC Cancer, 2022
Background Management of bladder cancer (BLCA) has not changed significantly in the past few decades, with platinum agent chemotherapy being used in most cases.
Sayani Bhattacharjee   +7 more
doaj   +1 more source

Three Epigenetic Biomarkers, GDF15, TMEFF2, and VIM, Accurately Predict Bladder Cancer from DNA-Based Analyses of Urine Samples [PDF]

open access: yes, 2010
Purpose: To identify a panel of epigenetic biomarkers for accurate bladder cancer (BlCa) detection in urine sediments. Experimental Design: Gene expression microarray analysis of BlCa cell lines treated with 5-aza-2′-deoxycytidine and ...
Ângelo Rodrigues   +12 more
core   +1 more source

Supplementary Material for: ANLN Serves as an Oncogene in Bladder Urothelial Carcinoma via Activating JNK Signaling Pathway [PDF]

open access: yes, 2022
Introduction: To understand the significance of ANLN (anillin, actin-binding protein)-mediated c-Jun N-terminal kinase (JNK) signal pathway on the progression of bladder urothelial carcinoma (BLCA).
Chen F. (4120777)   +3 more
core   +1 more source

Identification of tryptophan metabolism- and immune-related genes signature and prediction of immune infiltration landscape in bladder urothelial carcinoma

open access: yesFrontiers in Immunology, 2023
IntroductionTryptophan metabolism is indirectly involved in immune tolerance and promotes response to anticancer drugs. However, the mechanisms underlying tryptophan metabolism and immune landscape in bladder urothelial carcinoma (BLCA) are not fully ...
Guanwen Zhou   +4 more
doaj   +1 more source

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