Results 51 to 60 of about 15,201 (184)

Identifying prognostic characteristics of m6A-related glycolysis gene and predicting the immune infiltration landscape in bladder cancer

Cancer Cell International, 2023
Backgrounds Glucose metabolism is associated with the development of cancers, and m6A RNA methylation regulator-related genes play vital roles in bladder urothelial carcinoma (BLCA).
Guanwen Zhou, Yi Li, Xiangguo Ren, Guoliang Qin, Zhaocun Zhang, Haifeng Zhao, Lijian Gao, Xianzhou Jiang   +7 more
doaj   +1 more source

Comprehensive transcriptomic analysis of cell lines as models of primary tumors across 22 tumor types. [PDF]

, 2019
Cancer cell lines are a cornerstone of cancer research but previous studies have shown that not all cell lines are equal in their ability to model primary tumors.
Aran, D, Butte, AJ, Charalel, J, Chen, B, Goldstein, T, Sirota, M, van 't Veer, LJ, Wolf, DM, Yau, C, Yu, K   +9 more
core   +1 more source

TEAD4 functions as a prognostic biomarker and triggers EMT via PI3K/AKT pathway in bladder cancer

Journal of Experimental & Clinical Cancer Research, 2022
Background The distant metastasis is the primary cause of cancer morbidity and mortality for bladder cancer (BLCA) paitents. All the recommended therapy for it largely depends on how far the cancer has invaded.
Ming Chi, Jiao Liu, Chenxue Mei, Yaxing Shi, Nanqi Liu, Xuefeng Jiang, Chang Liu, Nan Xue, Hong Hong, Jisheng Xie, Xun Sun, Bo Yin, Xin Meng, Biao Wang   +13 more
doaj   +1 more source

Prediction of inherited genomic susceptibility to 20 common cancer types by a supervised machine-learning method. [PDF]

, 2018
Prevention and early intervention are the most effective ways of avoiding or minimizing psychological, physical, and financial suffering from cancer. However, such proactive action requires the ability to predict the individual's susceptibility to cancer
Kim, Byung-Ju, Kim, Sung-Hou
core   +2 more sources

Development of a prognostic model to predict BLCA based on anoikis-related gene signature: preliminary findings

BMC Urology, 2023
Abstract Background The prevalence of bladder urothelial carcinoma (BLCA) is significant on a global scale. Anoikis is a type of procedural cell death that has an important role in tumor invasion and metastasis. The advent of single-cell RNA sequencing (scRNA-seq) approaches has revolutionized the genomics field by ...
Shusheng Zhu, Qingsong Zhao, Yanpeng Fan, Chao Tang   +3 more
openaire   +3 more sources

PARP inhibitors chemopotentiate and synergize with cisplatin to inhibit bladder cancer cell survival and tumor growth

BMC Cancer, 2022
Background Management of bladder cancer (BLCA) has not changed significantly in the past few decades, with platinum agent chemotherapy being used in most cases.
Sayani Bhattacharjee, Matthew J. Sullivan, Rebecca R. Wynn, Alex Demagall, Andrew S. Hendrix, Puneet Sindhwani, Firas G. Petros, Nagalakshmi Nadiminty   +7 more
doaj   +1 more source

Identification of tryptophan metabolism- and immune-related genes signature and prediction of immune infiltration landscape in bladder urothelial carcinoma

Frontiers in Immunology, 2023
IntroductionTryptophan metabolism is indirectly involved in immune tolerance and promotes response to anticancer drugs. However, the mechanisms underlying tryptophan metabolism and immune landscape in bladder urothelial carcinoma (BLCA) are not fully ...
Guanwen Zhou, Guoliang Qin, Zhaocun Zhang, Haifeng Zhao, Linlin Xue   +4 more
doaj   +1 more source

Identification of integrin drug targets for 17 solid tumor types. [PDF]

, 2018
Integrins are contributors to remodeling of the extracellular matrix and cell migration. Integrins participate in the assembly of the actin cytoskeleton, regulate growth factor signaling pathways, cell proliferation, and control cell motility.
Arun, Adith S, Lam, Kit S, Tepper, Clifford G   +2 more
core   +1 more source

A Multi-Method Approach for Proteomic Network Inference in 11 Human Cancers. [PDF]

, 2016
Protein expression and post-translational modification levels are tightly regulated in neoplastic cells to maintain cellular processes known as 'cancer hallmarks'.
Bemis, D., Ciriello, G., Sander, C., Schultz, N., Sánchez-Vega, F., Sümer, S.O., Şenbabaoğlu, Y.   +6 more
core   +3 more sources

Prognostic value of LncRNA DLGAP1-AS2 in bladder cancer and its regulatory effect on tumor progression

Discover Oncology
Background Bladder cancer (BLCA) represents one of the most prevalent malignant neoplasms within the urinary system, and its incidence is progressively rising annually in China.
Yuhui Zhao, Xiaotong Wu, Yi Zheng, Huiming Bai, Zhihang Zhang, Mingzhi Li, Xiaofeng He, Chao Yu   +7 more
doaj   +1 more source