Results 61 to 70 of about 15,201 (184)

PRR11 is a prognostic biomarker and correlates with immune infiltrates in bladder urothelial carcinoma

Scientific Reports, 2023
Abnormal proline-rich protein 11 (PRR11) expression is associated with various tumors. However, there are few reports concerning PRR11 with prognostic risk, immune infiltration, or immunotherapy of bladder urothelial carcinoma (BLCA). This study is based
Wenpeng Ni, Lijuan Yi, Xiaoru Dong, Mengjie Cao, Jinjuan Zheng, Qingling Wei, Chunlei Yuan   +6 more
doaj   +1 more source

Prediction of Prognosis and Recurrence of Bladder Cancer by ECM-Related Genes

Journal of Immunology Research, 2022
Background. Bladder cancer (BLCA) is one of the most common cancers and ranks ninth among all cancers. Extracellular matrix (ECM) genes activate a number of pathways that facilitate tumor development.
Hongfan Zhao, Zihao Chen, Yunze Fang, Mingqiang Su, Yipeng Xu, Zhifeng Wang, Michael Adu Gyamfi, Junfeng Zhao   +7 more
doaj   +1 more source

Screening ANLN and ASPM as bladder urothelial carcinoma-related biomarkers based on weighted gene co-expression network analysis

Frontiers in Genetics, 2023
Introduction: Bladder cancer (BLCA) is one of the most common malignancies in the urinary system with a poor prognosis and high treatment costs. Identifying potential prognostic biomarkers is significant for exploring new therapeutic and predictive ...
Tenghao Yang, Zepai Chi, Guoyuan Liu, Xuwei Hong, Sizhe Cao, Kequan Cheng, Yonghai Zhang   +6 more
doaj   +1 more source

Absence of an embryonic stem cell DNA methylation signature in human cancer. [PDF]

, 2019
BackgroundDifferentiated cells that arise from stem cells in early development contain DNA methylation features that provide a memory trace of their fetal cell origin (FCO). The FCO signature was developed to estimate the proportion of cells in a mixture
Christensen, Brock C, Kelsey, Karl T, Koestler, Devin C, Salas, Lucas A, Wiencke, John K, Zhang, Ze   +5 more
core  

Menin facilitates the cell proliferation of bladder cancer via modulating the TFAP2C/β-catenin axis

Genes and Diseases
Bladder cancer (BLCA) is a common malignant tumor of the urinary system, with significant morbidity and mortality rates worldwide. The MEN1 gene, encoding the menin protein, plays a regulatory role in several cancers. However, the role played by menin in
Qing Shi, Xiang Pan, Shiheng Zhang, Mengyuan Wu, Meiqi Xu, Yun-Qi Li, Li Zhong, Zi-Qi Wang, Wanhai Xu, Yakun Luo   +9 more
doaj   +1 more source

The Relationship of Pyroptosis-Related Genes, Patient Outcomes, and Tumor-Infiltrating Cells in Bladder Urothelial Carcinoma (BLCA)

Frontiers in Pharmacology, 2022
Introduction: The role of pyroptosis and its effects on tumor-infiltrating cells (TICs) in the pathogenesis and treatment outcomes of patients with bladder urothelial carcinoma (BLCA) remains unclear.Methods: We conducted a bioinformatics analysis on the pyroptosis-related genes (PRGs) and TICs using data from public domains, and evaluated their impact
Ruiyan Xie, Ming Xie, Litong Zhu, Joanne W. Y. Chiu, Wayne Lam, Desmond Y. H. Yap   +5 more
openaire   +3 more sources

Pathway-based cancer transcriptome deciphers a high-resolution intrinsic heterogeneity within bladder cancer classification

Journal of Translational Medicine
Background The heterogeneity of bladder cancer (BLCA) is affected by its inherent transcriptional properties and tumor microenvironment (TME). Stromal transcriptional components in the TME significantly influence the transcriptional classification of ...
Zhan Wang, Zhaokai Zhou, Shuai Yang, Zhengrui Li, Run Shi, Ruizhi Wang, Kui Liu, Xiaojuan Tang, Qi Li   +8 more
doaj   +1 more source

INTEGRATIVE ANALYSIS OF OMICS DATA IN ADULT GLIOMA AND OTHER TCGA CANCERS TO GUIDE PRECISION MEDICINE [PDF]

, 2017
Transcriptomic profiling and gene expression signatures have been widely applied as effective approaches for enhancing the molecular classification, diagnosis, prognosis or prediction of therapeutic response towards personalized therapy for cancer ...
hu, Xin, hu, xin
core   +1 more source

The multi-omic landscape of transcription factor inactivation in cancer [PDF]

, 2016
BACKGROUND: Hypermethylation of transcription factor promoters bivalently marked in stem cells is a cancer hallmark. However, the biological significance of this observation for carcinogenesis is unclear given that most of these transcription factors ...
Beck, S, Feber, A, Teschendorff, AE, Widschwendter, M, Yang, Z, Zheng, SC   +5 more
core   +1 more source

α-E-Catenin (CTNNA1) Inhibits Cell Proliferation, Invasion and EMT of Bladder Cancer

Cancer Management and Research, 2020
Qiang Chi, Hui Xu, Dianbin Song, Zhiyong Wang, Zemin Wang, Guang Ma Department of Urology, Affiliated Hospital of Chengde Medical University, Chengde 067000, People’s Republic of ChinaCorrespondence: Qiang ChiDepartment of Urology, Affiliated ...
Chi Q, Xu H, Song D, Wang Z, Wang Z, Ma G   +5 more
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