Extracranial, Extragonadal Germ Cell Tumors: A Multicenter Australian Case Series
Asia-Pacific Journal of Clinical Oncology, EarlyView.Extragonadal germ cell tumors (EGCTs) are rare, with limited prospective data to guide treatment or inform prognosis. Incidence and treatment patterns of EGCT in Australia reflect international data and practices. Compared to testicular primaries, the prognosis of EGCT is poor, especially for primary mediastinal non‐seminoma.
Kar Ven Cavan Chow +19 more
wiley +1 more source
Bioanalytical method development and validation of bleomycin sulphate
Journal of Applied Pharmaceutical Research, 2017 Bleomycin is an anti-neoplastic drug that has recently been used for the treatment of vascular anomalies. An expedient method was developed for the determination of plasma bleomycin levels using ion-paired reversed phase high performance liquid ...
Yash Prashar +2 more
doaj
The Protective Effect of Naringin against Bleomycin-Induced Pulmonary Fibrosis in Wistar Rats
Pulmonary Medicine, 2016 The aim of the current study was to investigate the protective effect of naringin on bleomycin-induced pulmonary fibrosis in rats. Twenty-four Wistar rats randomly divided into four groups (control, bleomycin alone, bleomycin + naringin 40, and bleomycin
Nergiz H. Turgut +5 more
doaj +1 more source
Protein kinase Cδ and c-Abl kinase are required for transforming growth factor β induction of endothelial-mesenchymal transition in vitro. [PDF]
, 2011 OBJECTIVE: The origin of the mesenchymal cells responsible for the intimal fibrosis in systemic sclerosis (SSc) has not been fully identified. The present study was undertaken to investigate whether subendothelial mesenchymal cells may emerge through ...
Jimenez, Sergio A., Li, zhaodong
core +2 more sources
Protective Role for Itaconate During Inhaled Allergen Challenge
Allergy, EarlyView.Itaconate levels decrease in sputum following allergen inhalation in mild asthmatics, suggesting a dynamic metabolic response to airway challenge. Genetic deletion of Acod1 in mice did not alter airway inflammation or remodelling in response to chronic HDM exposure.
Gesa J. Albers +16 more
wiley +1 more source
Substrate specificity and structural investigation into PepO and PepW : two peptidases from Lactobacillus rhamnosus : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Biochemistry at Massey University, Palmerston North, New Zealand [PDF]
, 2005 The proteolytic systems of lactic acid bacteria have important roles in the maturation and flavour development of cheese. Lactic acid bacteria pepetidases contribute to the taste of cheese through the production of low-molecular weight peptides and free ...
Yates, Karen Maree
core
Clinical Images: Methotrexate‐induced melanonychia
Arthritis &Rheumatology, EarlyView.
Yoshinori Taniguchi, Hirotaka Yamamoto
wiley +1 more source
Sperm Telomere Interactions Are Impaired in Testicular Cancer Before and After Adjuvant Therapy
Andrology, EarlyView.ABSTRACT Background No study has yet explored telomere length or interaction in sperm nuclei of testicular cancer (TC) patients exposed to chemotherapy or radiotherapy. However, sperm telomere dynamics have emerged as a potential marker in male infertility.
Benoit Berby +10 more
wiley +1 more source
Journal of InflammationEnvironmental tobacco smoke (ETS) is known to cause lung inflammatory and injurious responses. Smoke exposure is associated with the pathobiology related to lung fibrosis, whereas the mechanism that ETS exposure augments pulmonary fibrogenesis is unclear.
Qixin Wang +3 more
doaj +1 more source
The Effects of Silymarin in Bleomycin-Induced Pulmonary Fibrosis in Mice [PDF]
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2009 Background and Objectives: Silymarin, the active principle of Silybum marianum, has antifibrotic effects in hepatic fibrosis by several mechanisms. Since the pathogenesis of fibroproliferative diseases is similar, the effect of silymarin in bleomycin ...
L. Safaeian +3 more
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