IGF-1 enhances the osteogenic activity of BMP-6 in vitro and in vivo [PDF]
, 2017 Bone morphogenetic protein-2 (BMP-2) is widely used in orthopedic surgery and bone tissue engineering because of its strong osteogenic activity. However, BMP-2 treatments have several drawbacks and alternatives are being explored.
Becerra-Ratia, Jose +2 more
core
Parameterized Complexity of Asynchronous Border Minimization
, 2015 Microarrays are research tools used in gene discovery as well as disease and cancer diagnostics. Two prominent but challenging problems related to microarrays are the Border Minimization Problem (BMP) and the Border Minimization Problem with given ...
A Frank +16 more
core +1 more source
Pleading Securities Fraud [PDF]
, 2001 Hyaluronan based hydrogel coatings can mimic extracellular matrix components and incorporate growth factors that can be released during a progressive degradation while new tissue regenerates.
Bergman +39 more
core +4 more sources
Bmp induces osteoblast differentiation through both Smad4 and mTORC1 signaling [PDF]
, 2017 The bone morphogenetic protein (Bmp) family of secreted molecules has been extensively studied in the context of osteoblast differentiation. However, the intracellular signaling cascades that mediate the osteoblastogenic function of Bmp have not been ...
Karner, Courtney M +2 more
core +2 more sources
Salivary inflammatory biomarkers during initial orthodontic tooth movement [PDF]
, 2016 BACKGROUND: Orthodontic tooth movement is a complex process involving a number of inflammatory and anabolic/catabolic pathways. Further, successful treatment depends on proper timing of orthodontic measures with regard to patient’s growth spurt ...
Serrenho, Ana
core +1 more source
TGFβ/BMP immune signaling affects abundance and function of C. elegans gut commensals. [PDF]
, 2019 The gut microbiota contributes to host health and fitness, and imbalances in its composition are associated with pathology. However, what shapes microbiota composition is not clear, in particular the role of genetic factors.
Berg, Maureen +5 more
core +2 more sources
BMP signalling: agony and antagony in the family.
Trends in Cell Biology, 2015 Bone morphogenetic proteins (BMPs) are secreted extracellular matrix (ECM)-associated proteins that regulate a wide range of developmental processes, including limb and kidney formation.
D. Brazil +4 more
semanticscholar +1 more source
Nanoscale structure of the BMP antagonist chordin supports cooperative BMP binding [PDF]
Proceedings of the National Academy of Sciences, 2014 Significance Bone morphogenetic proteins (BMPs) are essential signaling molecules important in embryo development and maintaining tissue function in adulthood. BMPs are regulated outside the cell by inhibitors such as chordin. The structure of chordin is unknown as extracellular proteins are generally not suitable for high-resolution methods.
Troilo, Helen +8 more
openaire +4 more sources
IGF-1 enhances the osteogenic activity of BMP-6 in vitro and in vivo, and together have a stronger osteogenic effect than when IGF-1 is combined with BMP-2 [PDF]
, 2017 Bone morphogenetic protein-2 (BMP-2) is widely used in orthopedic surgery and bone tissue engineering because of its strong osteogenic activity. However, BMP-2 treatments have several drawbacks and alternatives are being explored.
Becerra-Ratia, Jose +2 more
core
Role of the bone morphogenic protein pathway in developmental haemopoiesis and leukaemogenesis [PDF]
, 2016 Myeloid leukaemias share the common characteristics of being stem cell-derived clonal diseases, characterised by excessive proliferation of one or more myeloid lineage.
Toofan, Parto, Wheadon, Helen
core +1 more source