Results 51 to 60 of about 272,370 (331)

The roles and regulatory mechanisms of TGF-β and BMP signaling in bone and cartilage development, homeostasis and disease

Cell Research
Transforming growth factor-βs (TGF-βs) and bone morphometric proteins (BMPs) belong to the TGF-β superfamily and perform essential functions during osteoblast and chondrocyte lineage commitment and differentiation, skeletal development, and homeostasis ...
Mengrui Wu, Shali Wu, Wei Chen, Yi-Ping Li   +3 more
semanticscholar   +1 more source

TNFα drives pulmonary arterial hypertension by suppressing the BMP type-II receptor and altering NOTCH signalling

Nature Communications, 2017
Heterozygous germ-line mutations in the bone morphogenetic protein type-II receptor (BMPR-II) gene underlie heritable pulmonary arterial hypertension (HPAH). Although inflammation promotes PAH, the mechanisms by which inflammation and BMPR-II dysfunction
Liam A. Hurst, B. Dunmore, L. Long, A. Crosby, R. Al‐Lamki, J. Deighton, M. Southwood, Xudong Yang, M. Nikolić, B. Herrera, G. Inman, J. Bradley, Amer A. Rana, P. Upton, N. Morrell   +14 more
semanticscholar   +1 more source

FID Fast Image Display for (.BMP & .PCX) Images [PDF]

Al-Rafidain Journal of Computer Sciences and Mathematics, 2004
Video display speed constitutes a very important factor in modern software performance. The best way to achieve fastest display is by accessing Video RAM and programming video card directly.
Rawaa Qasha, Ahmed Nori
doaj   +1 more source

Sequential BMP‐2/BMP‐7 delivery from polyester nanocapsules

Journal of Biomedical Materials Research Part A, 2009
AbstractThe aim of this study was to develop a nanosized, controlled growth factor release system to incorporate into tissue engineering scaffolds and thus activate the cells seeded in the scaffold. Nanocapsules of poly(lactic acid‐co‐glycolic acid) (PLGA) and poly(3‐hydroxybutyrate‐co‐3‐hydroxyvalerate) (PHBV) were loaded with the bone morphogenetic ...
Yilgor, P., Hasirci, N., Hasirci, V.
openaire   +3 more sources

BMP-9 interferes with liver regeneration and promotes liver fibrosis

Gut, 2017
Objective Bone morphogenetic protein (BMP)-9, a member of the transforming growth factor-β family of cytokines, is constitutively produced in the liver.
K. Breitkopf-Heinlein, C. Meyer, Courtney König, H. Gaitantzi, A. Addante, Mariam Thomas, E. Wiercinska, C. Cai, Qi Li, F. Wan, C. Hellerbrand, N. Valous, M. Hahnel, C. Ehlting, J. Bode, Stephanie Mueller-Bohl, U. Klingmüller, Jutta Altenöder, I. Ilkavets, M. Goumans, L. Hawinkels, Se-Jin Lee, M. Wieland, C. Mogler, M. Ebert, B. Herrera, H. Augustin, Aránzazu Sánchez, S. Dooley, P. ten Dijke   +29 more
semanticscholar   +1 more source

GLM for Image Steganography Technique [PDF]

Al-Rafidain Journal of Computer Sciences and Mathematics, 2013
An improvement to a Steganography method for hiding data using Gray Level Images is proposed in this paper. The method is an improvement over earlier method named Least Significant Bit (LSB).
Ahmed Nori, Noor Ahmed, Thana Ahmed
doaj   +1 more source

Interplay between BMPs and Reactive Oxygen Species in Cell Signaling and Pathology

Biomolecules, 2019
The integration of cell extrinsic and intrinsic signals is required to maintain appropriate cell physiology and homeostasis. Bone morphogenetic proteins (BMPs) are cytokines that belong to the transforming growth factor-β (TGF-β) superfamily ...
Cristina Sánchez-de-Diego, José Antonio Valer, Carolina Pimenta-Lopes, José Luis Rosa, Francesc Ventura   +4 more
doaj   +1 more source

Bmp induces osteoblast differentiation through both Smad4 and mTORC1 signaling [PDF]

, 2017
The bone morphogenetic protein (Bmp) family of secreted molecules has been extensively studied in the context of osteoblast differentiation. However, the intracellular signaling cascades that mediate the osteoblastogenic function of Bmp have not been ...
Karner, Courtney M, Lee, Seung-Yon, Long, Fanxin   +2 more
core   +2 more sources

Systems biology derived source-sink mechanism of BMP gradient formation

eLife, 2017
A morphogen gradient of Bone Morphogenetic Protein (BMP) signaling patterns the dorsoventral embryonic axis of vertebrates and invertebrates. The prevailing view in vertebrates for BMP gradient formation is through a counter-gradient of BMP antagonists ...
Joseph M. Zinski, Ye Bu, Xu Wang, Wei Dou, David M. Umulis, M. Mullins   +5 more
semanticscholar   +1 more source

Biomechanical stress provides a second hit in the establishment of BMP/TGFβ-related vascular disorders

Cell Stress, 2020
Cardiovascular disorders are still the leading cause for mortality in the western world and challenge economies with steadily increasing healthcare costs.
Christian Hiepen, Jerome Jatzlau, Petra Knaus   +2 more
doaj   +1 more source