Results 81 to 90 of about 52,292 (275)

The Generation Of Novelty: The Province Of Developmental Biology [PDF]

open access: yes, 2006
A response to Michael Ruse\u27s Forty Years A Philosopher Of Biology: Why EvoDevo Makes Me Still Excited About My Subject
Gilbert, Scott F.
core   +2 more sources

The Wnt Effector TCF7l2 Promotes Oligodendroglial Differentiation by Repressing Autocrine BMP4-Mediated Signaling

open access: yesJournal of Neuroscience, 2020
Promoting oligodendrocyte (OL) differentiation represents a promising option for remyelination therapy for treating the demyelinating disease multiple sclerosis (MS).
Sheng Zhang   +10 more
semanticscholar   +1 more source

Determining the function of nuclear Bmp4

open access: yesThe FASEB Journal, 2009
Bone morphogenetic protein 4 (Bmp4) is a well known growth factor that regulates gene expression through the SMAD signaling pathway. Bmp4 is involved in many developmental processes and has been identified as an important factor in several cancers, including melanoma, ovarian cancer, and colon cancer ...
Trina J Loos, Laura C Bridgewater
openaire   +1 more source

Near‐Infrared Organic Photovoltaic Electrodes for Subretinal Neurostimulation

open access: yesAdvanced Functional Materials, EarlyView.
Organic photovoltaic electrodes based on the D18:Y6 blend enable precise and light‐controlled activation of retinal ganglion cells in a degenerating retina. NIR Light‐driven activation of retinal ganglion cells, tunable stimulation parameters, and biocompatibility with human retinal organoids highlight their potential for next‐generation prosthetics ...
Andrea Corna   +10 more
wiley   +1 more source

Generation of an expandable intermediate mesoderm restricted progenitor cell line from human pluripotent stem cells. [PDF]

open access: yes, 2015
The field of tissue engineering entered a new era with the development of human pluripotent stem cells (hPSCs), which are capable of unlimited expansion whilst retaining the potential to differentiate into all mature cell populations.
Brafman, David   +8 more
core   +3 more sources

RNA sequencing reveals BMP4 as a basis for the dual-target treatment of diabetic retinopathy

open access: yesJournal of molecular medicine, 2020
Diabetic retinopathy (DR), currently considered as a neurovascular disease, has become the major cause of blindness. More and more scholars believe that DR is no longer just a kind of microvascular disease, but accompanied by retinal neurodegenerative ...
Lijie Dong   +6 more
semanticscholar   +1 more source

BMP4 Regulates Pancreatic Progenitor Cell Expansion through Id2 [PDF]

open access: yesJournal of Biological Chemistry, 2006
Inhibitor of DNA binding (Id) proteins bind to and inhibit the function of basic helix-loop-helix (bHLH) transcription factors including those that regulate pancreatic development. Moreover, bone morphogenetic proteins (BMPs) regulate the expression of Ids.
Hong, Hua   +6 more
openaire   +2 more sources

Platelet Lysate–Enriched Human Induced Pluripotent Stem Cell–Derived Chondrocyte Sheets for Bone Defect Repair via Endochondral Ossification

open access: yesAdvanced Healthcare Materials, EarlyView.
Human iPSC‐derived hypertrophic chondrocyte sheet promotes bone regeneration. Abstract Bone defects are a major clinical challenge, primarily owing to the limited self‐healing capacity of bones and the high risk of complications associated with conventional treatment strategies.
Yiwei Chen   +9 more
wiley   +1 more source

Differential expression of a BMP4 reporter allele in anterior fungiform versus posterior circumvallate taste buds of mice

open access: yesBMC Neuroscience, 2010
Background Bone Morphogenetic Protein 4 (BMP4) is a diffusible factor which regulates embryonic taste organ development. However, the role of BMP4 in taste buds of adult mice is unknown. We utilized transgenic mice with LacZ under the control of the BMP4
Barlow Linda A, Nguyen Ha M
doaj   +1 more source

Bone morphogenetic protein 4 rescues the bone regenerative potential of old muscle-derived stem cells via regulation of cell cycle inhibitors

open access: yesStem Cell Research & Therapy, 2022
Background Bone morphogenetic protein 4 (BMP4) promotes the osteogenic differentiation and the bone regenerative potential of muscle-derived stem cells (MDSCs).
Haizi Cheng   +7 more
doaj   +1 more source

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