Results 101 to 110 of about 114,435 (209)

Role for TGF-beta superfamily signaling in telencephalic GABAergic neuron development. [PDF]

, 2010
Signaling mechanisms mediated by the Transforming Growth Factor-beta (TGF-beta) superfamily regulate a variety of developmental processes. Here we show that components of both bone morphogenetic protein/growth differentiation factor and TGF-beta/activin ...
Lee, Amie Y, Long, Jason E, Maira, Mario, Rubenstein, John LR, Stifani, Stefano   +4 more
core  

BMP-2-Driven Osteogenesis: A Comparative Analysis of Porcine BMSCs and ASCs and the Role of TGF-β and FGF Signaling

Biology
Mesenchymal stromal cells (MSCs), such as bone marrow-derived cells (BMSCs) and adipose-derived cells (ASCs), are key candidates for bone regeneration therapies but have not yet been integrated into standard clinical practice due to heterogeneity in ...
Roman Taday, Pascal Jungbluth, Sebastian Zensen, Thomas Krakau, Joachim Windolf, Michèle J. Hoffmann, Vera Grotheer   +6 more
doaj   +1 more source

Wdr68 Mediates Dorsal and Ventral Patterning Events for Craniofacial Development.

PLoS ONE, 2016
Birth defects are among the leading causes of infant mortality and contribute substantially to illness and long-term disability. Defects in Bone Morphogenetic Protein (BMP) signaling are associated with cleft lip/palate.
Estibaliz Alvarado, Mina Yousefelahiyeh, Greg Alvarado, Robin Shang, Taryn Whitman, Andrew Martinez, Yang Yu, Annie Pham, Anish Bhandari, Bingyan Wang, Robert M Nissen   +10 more
doaj   +1 more source

BMP/Dpp signaling and epithelial morphogenesis in Drosophila development [PDF]

, 2018
In this thesis, I mainly investigate how BMP/Dpp signaling is involved in development of the early pupal wing of Drosophila, and the mechanisms coupling Dpp signaling with morphogenesis.Tässä työssä tutkitaan lähinnä sitä, miten BMP / Dpp-signalointi on ...
Gui, Jinghua
core  

Biglycan : a multivalent proteoglycan providing structure and signals [PDF]

, 2013
Research over the past few years has provided fascinating results indicating that biglycan, besides being a ubiquitous structural component of the extracellular matrix (ECM), may act as a signaling molecule.
Năstase, Mădălina-Viviana, Schäfer, Liliana, Young, Marian F.   +2 more
core  

Signaling by BMP

Reactome - a curated knowledgebase of biological pathways, 2007
L Huminiecki, A Moustakas
openaire   +1 more source

SnapShot: BMP Signaling in Development

Cell, 2011
Dutko, James A., Mullins, Mary C.
openaire   +2 more sources

Ethanol Induces Craniofacial Defects in Bmp Mutants Independent of nkx2.3 by Elevating Cranial Neural Crest Cell Apoptosis

Biomedicines
Background: Craniofacial malformations lie at the heart of fetal alcohol spectrum disorders (FASDs). While there is growing evidence for a genetic component in FASDs, little is known of the cellular mechanisms underlying these ethanol-sensitive loci in ...
Hieu D. L. Vo, C. Ben Lovely
doaj   +1 more source

Molecular mechanism of BMP signal control by Twisted gastrulation

Nature Communications
Twisted gastrulation (TWSG1) is an evolutionarily conserved secreted glycoprotein which controls signaling by Bone Morphogenetic Proteins (BMPs). TWSG1 binds BMPs and their antagonist Chordin to control BMP signaling during embryonic development, kidney ...
Tomas Malinauskas, Gareth Moore, Amalie F. Rudolf, Holly Eggington, Hayley L. Belnoue-Davis, Kamel El Omari, Samuel C. Griffiths, Rachel E. Woolley, Ramona Duman, Armin Wagner, Simon J. Leedham, Clair Baldock, Hilary L. Ashe, Christian Siebold   +13 more
doaj   +1 more source

Methyl-Beta-Cyclodextrin Restores Aberrant Bone Morphogenetic Protein 2-Signaling in Bone Marrow Stromal Cells Obtained from Aged C57BL/6 Mice

Journal of Developmental Biology
During aging, disruptions in various signaling pathways become more common. Some older patients will exhibit irregular bone morphogenetic protein (BMP) signaling, which can lead to osteoporosis (OP)—a debilitating bone disease resulting from an imbalance
Daniel Halloran, Venu Pandit, Kelechi Chukwuocha, Anja Nohe   +3 more
doaj   +1 more source