Results 71 to 80 of about 905,740 (294)
Ter94/VCP is a novel component involved in BMP signaling.
PLoS ONE, 2014 Bone morphogenetic proteins (BMPs), a subgroup of the transforming growth factor (TGF)-β family, transduce their signal through multiple components downstream of their receptors.
Zhao Zeng +4 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.Dynamic compression enhances mesenchymal stromal cell proliferation in nonwoven PET scaffolds under chondrogenic differentiation conditions and triggers mechanosensitive transcriptional programs associated with extracellular matrix remodeling. These findings highlight the potential of mechanically stimulated PET scaffolds as a promising platform for ...
Graciosa Quelhas Teixeira +8 more
wiley +1 more source
Advanced Materials, EarlyView.Micro‐topographical cues applied through temporally controlled microscale confinement improve the reproducibility, spatial organization, and neurosensory‐associated features of pluripotent stem cell‐derived inner ear organoids. Integration with a vascularized organoid platform further enables controlled investigation of vascular‐epithelial interactions
Harshita Sharma +15 more
wiley +1 more source
Alk1 Signaling in Vascular Development [PDF]
, 2013 Heterozygous loss of the endothelial-specific transforming growth factor-beta (TGF-β) Type 1 receptor, activin receptor-like kinase 1 (ALK1), results in the autosomal dominant disorder, hereditary hemorrhagic telangiectasia type 2 (HHT2), which is ...
Laux, Derek William
core
Advanced Materials Interfaces, EarlyView.Graphene layers are fabricated on Cu foil and transferred onto glass substrates to form double‐ and multi‐layer G‐glass. Raman spectroscopy confirms structural integrity, while SEM and fluorescence microscopy reveal favorable adhesion and spreading of L‐929 fibroblast cells.
Mariana Mihaela Apostol +8 more
wiley +1 more source
Crosstalk between BMP and Notch Induces Sox2 in Cerebral Endothelial Cells
Cells, 2019 Bone morphogenetic protein (BMP) and Notch signaling are critical for endothelial cell (EC) differentiation in vascular development. Recent studies have shown that excess BMP activity induces Notch signaling in cerebral ECs resulting in arteriovenous ...
Xiuju Wu +8 more
doaj +1 more source
Direct response elements of BMP within the PV.1A promoter are essential for its transcriptional regulation during early Xenopus development. [PDF]
PLoS ONE, 2011 Xvent homeobox genes encode transcription factors that repress organizer genes and are essential for dorsoventral specification during early embryogenesis in Xenopus.
Hyun-Shik Lee +10 more
doaj +1 more source
Charting Endocrine Progenitors Across Species and Organs
Advanced Science, EarlyView.Endocrine progenitors give rise to the hormone‐producing cells of the pancreas and intestine. Using single‐cell multiomics and proteomics, this study compares these progenitors across species, systems, and organs, mapping the conserved and species‐specific gene regulatory networks that guide their formation.
Changying Jing +21 more
wiley +1 more source
Kekkon5 is an extracellular regulator of BMP signaling
Developmental Biology, 2009 Precise spatial and temporal control of Drosophila Bone Morphogenetic Protein (BMP) signaling is achieved by a host of extracellular factors that modulate ligand distribution and activity. Here we describe Kekkon5 (Kek5), a transmembrane protein containing leucine-rich repeats (LRRs), as a novel regulator of BMP signaling in Drosophila.
Evans, Timothy A. +2 more
openaire +2 more sources
Role of p63 in skin biology: its function in cell proliferation and differentiation [PDF]
, 2011 p63, a p53 family member, plays an essential role in epidermal development controlling several biological functions, some of which remain poorly understood.
Antonini, Dario
core +1 more source