Results 211 to 220 of about 21,955 (252)

Transcriptional dynamics uncover the role of BNIP3 in mitophagy during muscle remodeling in <i>Drosophila</i>. [PDF]

open access: yesElife
Taoka H   +11 more
europepmc   +1 more source

Coordinating BNIP3/NIX-mediated mitophagy in space and time

open access: yesBiochemical Society Transactions
Mitochondria maintain organellar homeostasis through multiple quality control pathways, including the clearance of defective or unwanted mitochondria by selective autophagy.
Natalie M. Niemi, Jonathan R. Friedman
semanticscholar   +3 more sources
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An unexpected journey for BNIP3

Autophagy
Mitophagy is a cellular process that enables the selective degradation of damaged, dysfunctional, or superfluous mitochondria. During mitophagy, specific proteins recognize and tag mitochondria for degradation.
Jose M Delgado, C. Shoemaker
semanticscholar   +3 more sources

BNIP3 as a Regulator of Cisplatin-Induced Apoptosis

Biochemistry (Moscow), 2020
BNIP3 is a member of Bcl-2 protein family involved in regulation of various forms of cell death. However, its role in these processes remains unclear and varies depending on the type of cancer cells and environmental factors (pH, O2 level, etc.). Here, the role of BNIP3 in apoptosis regulation in lung adenocarcinoma cells was investigated.
A S, Gorbunova   +6 more
openaire   +2 more sources

BNIP3 and Nix: Atypical regulators of cell fate

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2022
Since their discovery nearly 25 years ago, the BCL-2 family members BNIP3 and BNIP3L (aka Nix) have been labelled 'atypical'. Originally, this was because BNIP3 and Nix have divergent BH3 domains compared to other BCL-2 proteins. In addition, this atypical BH3 domain is dispensable for inducing cell death, which is also unusual for a 'death gene ...
Jared T, Field, Joseph W, Gordon
openaire   +2 more sources

BNIP3 Regulation of Intracellular Calcium

The FASEB Journal, 2016
Necrotizing enterocolitis is the most common gastrointestinal emergency affecting low‐birth weight premature infants, with an incidence between 3% and 10% in infants less than 1500 grams, and mortality ranging from 15% to 30%. The pathogenesis of NEC is not clearly defined, but is likely a multifactorial disease wherein intestinal ischemia and hypoxia ...
Jared Field   +5 more
openaire   +1 more source

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