HMOX1 interacts with BNIP3 to modulate neuronal ferroptosis after spinal cord ischemia-reperfusion injury via a mitophagy-dependent mechanism. [PDF]
Duan Y +10 more
europepmc +1 more source
Hypoxic BMSC-derived exosomes-induced mitophagy quenches intestinal inflammation via HIF-1α/BNIP3 pathway. [PDF]
Zhu F +9 more
europepmc +1 more source
Mitophagy in breast cancer: Regulatory mechanisms and therapeutic potential. [PDF]
Chang Y +9 more
europepmc +1 more source
Mitophagy-driven prognosis in pediatric acute myeloid leukemia: a new frontier. [PDF]
Kumar RR +14 more
europepmc +1 more source
Receptor-mediated mitophagy: a new target of neurodegenerative diseases. [PDF]
Yang J +5 more
europepmc +1 more source
Functional Dissection of BH3 Only Protein BNIP3
BNIP3 is a pro-apoptotic protein, which contains BH3 and trans-membrane domains. Previous studies demonstrated an association between ceBNIP3, C. elegans homologue of BNIP3, and ced-3. It seemed likely that the interaction between ceBNIP3 and ced-3 was an alternative cascade of caspase activation in C.
openaire
Mechanism of autophagy initiation by transmembrane selective autophagy receptors. [PDF]
Adriaenssens E, Martens S.
europepmc +1 more source
Methylated BNIP3 gene in colorectal cancer prognosis
The DNA methylation of apoptosis-related genes in various cancers contributes to the disruption of the apoptotic pathway and results in resistance to chemotherapeutic agents. Irinotecan (CPT-11) is one of the key chemotherapy drugs used to treat metastatic colorectal cancer (CRC).
openaire
BNIP3L/BNIP3-Mediated Mitophagy Contributes to the Maintenance of Ovarian Cancer Stem Cells. [PDF]
Li N +14 more
europepmc +1 more source
Docosahexaenoic Acid Modulates Autophagy and Confers Neuronal Resilience under Hypoxia-Reoxygenation Stress. [PDF]
Zamora F +5 more
europepmc +1 more source

