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Functions of BNIP3 in Nutrient Stress Responses
2019BNIP3 is a mitophagy receptor that targets mitochondria for degradation at the autophagolysosome. By mediating mitophagy, BNIP3 functions to decrease mitochondrial mass as an adaptive response to stress, namely hypoxia and nutrient starvation. This catabolic mechanism prevents the accumulation of damaging reactive oxygen species that are normally ...
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BNIP3 is degraded by ULK1-dependent autophagy via MTORC1 and AMPK
Autophagy, 2013Eung-Sam Kim +2 more
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Response to myocardial ischemia/reperfusion injury involves Bnip3 and autophagy
Cell Death and Differentiation, 2006Asa Gustafsson +2 more
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Enhancing lysosome biogenesis attenuates BNIP3-induced cardiomyocyte death
Autophagy, 2012Abhinav Diwan, Haiyan Liu, Xiucui Ma
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The role of Bcl-2 family member BNIP3 in cell death and disease: NIPping at the heels of cell death
Cell Death and Differentiation, 2009S B Gibson
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BNIP3 subfamily BH3-only proteins: mitochondrial stress sensors in normal and pathological functions
Oncogene, 2009G Chinnadurai +2 more
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BNIP3 Interacting with LC3 Triggers Excessive Mitophagy in Delayed Neuronal Death in Stroke
CNS Neuroscience and Therapeutics, 2014Spencer Gibson, Xingshun Xu
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