Proteomics analysis reveals progesterone receptor induced mitochondria-mediated apoptosis in breast cancer cells. [PDF]
Woo QY +10 more
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Quercetin prevents age-related hearing loss in C57BL/6J mice by activating mitophagy and inhibiting the NLRP3 inflammasome. [PDF]
Feng M +6 more
europepmc +1 more source
TFAP2A induces cisplatin resistance via BNIP3-mediated mitophagy in non-small cell lung cancer. [PDF]
Guo LL, Yang XH, Jin HZ, Tian L.
europepmc +1 more source
Oxidative stress-mediated impairment of human trophoblast cell proliferation by zinc pyrithione exposure. [PDF]
Wang X +5 more
europepmc +1 more source
Mitophagy in gastrointestinal tumors: mechanisms and new targets for immunotherapy. [PDF]
Zhang T +7 more
europepmc +1 more source
Cyclic tensile loading regulates nucleus pulposus cell autophagy through mitochondrial dynamics: molecular mechanisms and implications. [PDF]
Xue S, Soleimani Samarkhazan H.
europepmc +1 more source
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An unexpected journey for BNIP3
AutophagyMitophagy is a cellular process that enables the selective degradation of damaged, dysfunctional, or superfluous mitochondria. During mitophagy, specific proteins recognize and tag mitochondria for degradation. These tagged mitochondria are engulfed by specialized structures called phagophores that then mature into autophagosomes/mitophagosomes ...
José M Delgado, Christopher J Shoemaker
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BNip3 and signal-specific programmed death in the heart
Journal of Molecular and Cellular Cardiology, 2005The BH3-only proteins, including BNip3, are members of the Bcl-2 family of cell death-regulating factors. Whereas proteins such as Bax and Bak play a central role in most forms of apoptosis, the BH3-only proteins appear to modulate apoptosis through cell type- and signal-specific pathways.
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BNIP3 Regulation of Intracellular Calcium
The FASEB Journal, 2016Necrotizing enterocolitis is the most common gastrointestinal emergency affecting low‐birth weight premature infants, with an incidence between 3% and 10% in infants less than 1500 grams, and mortality ranging from 15% to 30%. The pathogenesis of NEC is not clearly defined, but is likely a multifactorial disease wherein intestinal ischemia and hypoxia ...
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