Results 211 to 220 of about 213,033 (265)

Production and Purification of Mesenchymal Stem Cell‐Derived Extracellular Vesicles Using Preferential Exclusion Chromatography

open access: yesELECTROPHORESIS, EarlyView.
A scalable purification strategy using hydroxyl (OH) monolithic chromatography enables efficient isolation and direct concentration of MSC‐EVs from adherent and microcarrier‐based upstreams. This approach supports process scale‐up while ensuring high purity suitable for therapeutic EV manufacturing.
Katja Vrabec   +8 more
wiley   +1 more source

Clinical and research applications of synthetic bone substitutes in equine veterinary medicine: A systematic review

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Bone grafting in equine medicine offers a promising contribution to treating orthopaedic developmental diseases and chondral, osteochondral and segmental bone defects. Among grafts, synthetic bone substitutes—alloplastics—show favourable biological properties addressing numerous limitations presented by autografts, xenografts and ...
Katarzyna Skierbiszewska   +6 more
wiley   +1 more source

Mass culture of equine synovial fluid‐derived mesenchymal stromal cells using nonwoven polyethylene terephthalate fabrics

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Culture protocols need to yield 100 million equine synovial fluid (SF)‐derived mesenchymal stromal cells (SF‐MSCs) in around 3 weeks are needed, before these cells can be evaluated as agents of articular repair in clinical trials. Objectives To investigate mass culture of equine SF‐MSC culture protocols using nonwoven polyethylene ...
Miho Daniel Yoshitomi   +5 more
wiley   +1 more source

Review of articular cartilage repair techniques and their application in the horse

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Articular cartilage lesions represent a significant career‐limiting problem in athletic horses. A healthy articular cartilage surface is vital for optimal joint function, and defects can result in irreversible degenerative changes. Successful treatment of cartilage lesions remains a long‐standing challenge for orthopaedic surgeons, prompting ...
Charlotte K. Barton   +2 more
wiley   +1 more source

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