Results 231 to 240 of about 125,148 (266)
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Mesenchymal stromal/stem cells markers in the human bone marrow
Cytotherapy, 2013Mesenchymal stromal/stem cells (MSCs) can be isolated from human bone marrow (BM), expanded ex vivo and identified via numerous surface antigens. Despite the importance of these cells in regenerative therapy programs, it is unclear whether the cell membrane signature defining MSC preparations ex vivo is determined during culture or may reflect an in ...
RASINI, Valeria +7 more
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Characterization of bone marrow-derived mesenchymal stem cells in aging
Bone, 2015Adult mesenchymal stem cells are a resource for autologous and allogeneic cell therapies for immune-modulation and regenerative medicine. However, patients most in need of such therapies are often of advanced age. Therefore, the effects of the aged milieu on these cells and their intrinsic aging in vivo are important considerations.
Rocky Tuan
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The characteristics of human cranial bone marrow mesenchymal stem cells
Neuroscience Letters, 2015Recently, cell-based therapy has attracted attention for treatment of central nervous system (CNS) disorders. Bone marrow-derived mesenchymal stem cells (BMSCs) are considered to have good engraftment potential. Therefore, more efficient and less invasive methods to obtain donor cells are required.
Katsuhiro Shinagawa +10 more
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Bone marrow-derived mesenchymal stem cells and the tumor microenvironment
Cancer and Metastasis Reviews, 2010Over the last decade, there has been a growing interest in the role of mesenchymal stem cells (MSC) in cancer progression. These cells have the potential to give rise to a variety of mesenchymal cells like osteoblasts, chondrocytes, adipocytes, fibroblasts, and muscle cells. In contrast to their hematopoetic counterparts, MSC are not as clearly defined,
Scott A, Bergfeld, Yves A, DeClerck
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Isolation of Pig Bone Marrow-Derived Mesenchymal Stem Cells
2016Large animal models are an important preclinical tool for the evaluation of new interventions and their translation into clinical practice. The pig is a widely used animal model in multiple clinical fields, such as cardiology and orthopedics, and has been at the forefront of testing new therapeutics, including cell-based therapies.
Dries A M, Feyen +5 more
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Bone Marrow Mesenchymal Stem Cells: Agents of Immunomodulation and Neuroprotection
Current Stem Cell Research & Therapy, 2011Mesenchymal stromal cells (MSC) are part of the bone marrow stem cells repertoire which also includes the main stem cells population of the bone marrow, the hematopoietic stem cells. The main role of MSCs is to support hematopoiesis but they can also give rise to cells of the mesodermal layers.
Ibrahim, Kassis +2 more
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[Immunocharacteristics of bone marrow mesenchymal stem cell].
Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2010To study the immunocharacteristics of bone marrow mesenchymal stem cell (MSC) and provide experimental evidence for the potential therapeutic application.MSCs were isolated from rat bone marrow and confirmed by immunophenotype, and the growth dynamic and cell cycle were analyzed. MSCs were cultured with or without 200 U/ml interferon gamma (IFNg) , the
Zai-Fa, Hong +2 more
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Culture and Characterization of Human Bone Marrow Mesenchymal Stem Cells
2007Bone marrow (BM) mesenchymal stem cells (MSCs) are non-hematopoietic cells capable of generating colonies of plastic-adherent marrow mesenchymal cells, each derived from a single cell termed a colony-forming unit fibroblasts (CFU-Fs). In addition to their role in establishing the marrow microenvironment, these cells have been shown to differentiate ...
Bruno, Delorme, Pierre, Charbord
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Mesenchymal Stem Cells Derived from Human Bone Marrow
2015Mesenchymal stem cells are found in a number of tissues and have the potential to differentiate into a range of mesenchymal lineages. This ready availability and multipotent character means that mesenchymal stem cells have become a focus for the field of tissue engineering, particularly for the repair of bone and cartilage.
Gardner OF, Alini M, Stoddart MJ
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[Characterization of bone marrow mesenchymal stem cells.]
Clinical calcium, 2017Bones support the body as part of the human musculoskeletal system. They also contain bone marrow, which is a site of hematopoiesis. Bone marrow mesenchymal stem cells play a vital role by regulating skeletal tissue formation and maintaining hematopoiesis.
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