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Bone marrow-derived mesenchymal stem cells
Leukemia & Lymphoma, 2005Human mesenchymal stem cells (MSCs) contribute to the regeneration of mesenchymal tissues, and are essential in providing support for the growth and differentiation of primitive hemopoietic cells within the bone marrow microenvironment. Techniques are now available to isolate human MSCs and manipulate their expansion in vitro under defined culture ...
Kemp, KC, Hows, J, Donaldson, C
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Odontogenic Potential of Bone Marrow Mesenchymal Stem Cells
Journal of Oral and Maxillofacial Surgery, 2007This study aimed to investigate the odontogenic potential of bone marrow mesenchymal stem cells (BM-MSCs) for seeding in tooth regeneration.In this study, BM-MSCs were co-cultured with oral epithelial cells derived from rat embryos. Expression of the odontogenic genes Pax9, DMP1, and DSPP was detected by the reverse-transcription polymerase chain ...
Zhi-Yong, Li +5 more
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Human Bone Marrow Native Mesenchymal Stem Cells
Regenerative Medicine, 2008The adult bone marrow (BM) has been generally considered to be composed of hematopoietic tissue and the associated supporting stroma. There is accumulating evidence that a subset of multipotential cells exists within the latter compartment, commonly referred to as mesenchymal stem cells (MSCs).
Charalampos, Pontikoglou +2 more
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Germ cell differentiation of bone marrow mesenchymal stem cells
Andrologia, 2019Bone marrow mesenchymal stem cells (BM-MSCs) were first cultured under induction of retinoic acid (RA), Sertoli cells conditioned medium and RA + con (conditioned medium) as treatment groups. The presence of Sertoli cells was confirmed by immunocytochemistry of follicle-stimulating hormone receptor in Sertoli cells and flow cytometry by anti-Gata4 ...
Maryam Salem +3 more
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Microenvironment and stem properties of bone marrow‐derived mesenchymal cells
Wound Repair and Regeneration, 2001Adult stem cells are self‐renewing, pluripotent, and able to repopulate the tissue in which they reside. Cells endowed with these properties have been isolated from several tissues and an increasing number of reports provide evidence of their ability, following transplantation, to engraft host tissues other than those of their origin.
BIANCHI G +5 more
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Bone Marrow Mesenchymal Stem Cells Promote the Stemness of Hypopharyngeal Cancer Cells
Cellular Reprogramming, 2020A study was to investigate the regulation of bone marrow mesenchymal stem cells (BMSCs) on the stemness of hypopharyngeal cancer cells (FaDu cells). Green fluorescent protein-labeled FaDu cells were cocultured with BMSCs and then were isolated. In vitro experiments, including cell cycle and apoptosis analyses and clonogenic and sphere formation assays,
Danyang, Li +6 more
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Isolation of Mouse Bone Marrow Mesenchymal Stem Cells
2016Mesenchymal stem cells (MSCs) were initially characterized as connective tissue progenitors resident in bone marrow, but have now been isolated from a variety of tissues and organs and shown to also exhibit potent tissue regenerative properties mediated largely via paracrine actions.
Siddaraju V, Boregowda +2 more
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Mesenchymal Stem Cells from Adult Bone Marrow
2008Mesenchymal stem cells (MSCs), sometimes referred to as marrow stromal cells or multipotential stromal cells, represent a class of adult progenitor cells capable of differentiation to several mesenchymal lineages. They can be isolated from many tissues although bone marrow has been used most often.
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Integral Therapeutic Potential of Bone Marrow Mesenchymal Stem Cells
Current Drug Targets, 2005Bone marrow derived mesenchymal stem cells (MSC) are adult stem cells that reside within the bone marrow compartment. In the traditional developmental model, adult stem cells are able to differentiate only to the tissue in which they reside. Recent data have challenged the committed fate of the adult stem cells, presenting evidence for their multi ...
I, Kan, E, Melamed, D, Offen
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Mesenchymal Stem Cell Content of Human Vertebral Bone Marrow
Transplantation, 2004Mesenchymal stem cells (MSCs) are capable of down-regulating alloimmune responses and promoting the engraftment of hematopoietic stem cells. MSCs may therefore be suitable for improving donor-specific tolerance induction in solid-organ transplantation.
Norbert, Ahrens +7 more
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