Results 1 to 10 of about 2,554,329 (307)
IL-20RB mediates tumoral response to osteoclastic niches and promotes bone metastasis of lung cancer
The Journal of Clinical Investigation, 2022 Bone is a common site of metastasis in lung cancer, but the regulatory mechanism remains incompletely understood. Osteoclasts are known to play crucial roles in osteolytic bone metastasis by digesting bone matrix and indirectly enhancing tumor ...
Yunfei He +19 more
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PLoS ONE, 2020 Bone is one of the most common sites of metastasis from advanced solid tumors. Bone metastasis is a leading cause of pain and increases the risk of skeletal-related events (SREs) in cancer patients.
Soojung Hong +4 more
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The Journal of Clinical Investigation, 2022 Therapeutics targeting osteoclasts are commonly used treatments for bone metastasis; however, whether and how osteoclasts regulate premetastatic niche and bone tropism are largely unknown.
Zhiying Yue +26 more
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Bone metastasis pattern of cancer patients with bone metastasis but no visceral metastasis
Journal of Bone Oncology, 2019 Background: Bone metastasis of cancer can be a result from systemic blood spreading or vertebral venous plexus spreading. Systemic blood pathway induced bone metastasis can happen in any bone in the body since the spreading is considered to be random ...
Mingyu Zhu +16 more
doaj +3 more sources
Cancer Communications, 2019 Bone metastasis is the leading cause of death in prostate cancer patients, for which there is currently no effective treatment. Since the bone microenvironment plays an important role in this process, attentions have been directed to the interactions ...
Xiangyu Zhang
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Risk factors of bone metastasis in lung adenocarcinoma [PDF]
BMC Pulmonary MedicineObjective To investigate the risk factors of bone metastasis in lung adenocarcinoma and construct a risk prediction model. Methods Patients with newly diagnosed primary lung adenocarcinoma admitted to our hospital between 1 March 2018 and 1 March 2023 ...
Zhongnian Cao +8 more
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A Predictive Nomogram for Early Death in Pheochromocytoma and Paraganglioma
Frontiers in Oncology, 2022 BackgroundPheochromocytoma (PHEO) and paraganglioma (PGL) are relatively rare neuroendocrine tumors. The factors affecting patients with early death remain poorly defined. We aimed to study the demographic and clinicopathologic pattern and to develop and
Huiyang Li +17 more
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The role of integrin family in bone metabolism and tumor bone metastasis
Cell Death Discovery, 2023 Integrins have been the research focus of cell-extracellular matrix adhesion (ECM) and cytokine receptor signal transduction. They are involved in the regulation of bone metabolism of bone precursor cells, mesenchymal stem cells (MSCs), osteoblasts (OBs),
Liwei Mao, Lian Wang, Jiake Xu, Jun Zou
semanticscholar +1 more source
Association between malnutrition and leucopenia in patients with osteosarcoma
Frontiers in Nutrition, 2022 Background and aimLeucopenia (LP) greatly limits the efficacy of chemotherapy in osteosarcoma patients. This study aimed to evaluate the nutritional status of osteosarcoma patients before chemotherapy, assess the risk of LP during the perichemotherapy ...
Haixiao Wu +21 more
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Theranostics, 2021 Rationale: Breast cancer preferentially develops osteolytic bone metastasis, which makes patients suffer from pain, fractures and spinal cord compression.
Xinxin Yuan +27 more
semanticscholar +1 more source