Results 11 to 20 of about 2,554,329 (307)

The 100 most cited papers on bone metastasis: A bibliometric analysis

Journal of Bone Oncology, 2022
Background: Over the past few decades, a vast number of articles focused on bone metastasis have been published. Bibliometric analysis is helpful to determine the qualities and characteristics and to reveal the influential articles in this field. Methods:
Huiyang Li, Haixiao Wu, Maxim A. Abakumov, Yao Xu, Yile Lin, Vladimir P. Chekhonin, Karl Peltzer, Kirellos Said Abbas, Shu Li, Chao Zhang   +9 more
doaj   +1 more source

Nomogram Predicts Risk and Prognostic Factors for Bone Metastasis of Pancreatic Cancer: A Population-Based Analysis

Frontiers in Endocrinology, 2022
Background The overall survival (OS) of pancreatic cancer (PC) patients with bone metastasis (BM) is extremely low, and it is pretty hard to treat bone metastasis. However, there are currently no effective nomograms to predict the diagnosis and prognosis
Wei Zhang, Lichen Ji, Xijun Wang, Senbo Zhu, Junchao Luo, Yin Zhang, Yu Tong, Fabo Feng, Yao Kang, Qing Bi   +9 more
semanticscholar   +1 more source

Genomic characterization and outcome evaluation of kinome fusions in lung cancer revealed novel druggable fusions

npj Precision Oncology, 2021
Kinase fusions represent an important type of somatic alterations that promote oncogenesis and serve as diagnostic markers in lung cancer. We aimed to identify the landscape of clinically relevant kinase fusions in Chinese lung cancer and to explore rare
Binghao Li, Hao Qu, Jing Zhang, Weibo Pan, Meng Liu, Xiaobo Yan, Xin Huang, Xuexin He, Dong Lin, Sisi Liu, Ruting Guan, Yong Wu, Qiuxiang Ou, Hua Bao, Youbin Xu, Xue Wu, Yang Shao, Nong Lin   +17 more
doaj   +1 more source

Non-cancer Causes of Death Following Initial Synchronous Bone Metastasis in Cancer Patients

Frontiers in Medicine, 2022
PurposeTo investigate the non-cancer causes of death (COD) in cancer patients with synchronous bone metastasis (BM) that is based on the Surveillance, Epidemiology, and End Results (SEER) database.MethodsThe retrospective cohort study included malignant ...
Yao Xu, Yao Xu, Basel Abdelazeem, Basel Abdelazeem, Kirellos Said Abbas, Yile Lin, Yile Lin, Haixiao Wu, Haixiao Wu, Fei Zhou, Fei Zhou, Karl Peltzer, Vladimir P. Chekhonin, Vladimir P. Chekhonin, Shu Li, Shu Li, Huiyang Li, Huiyang Li, Wenjuan Ma, Wenjuan Ma, Chao Zhang, Chao Zhang   +21 more
doaj   +1 more source

GDF15 promotes prostate cancer bone metastasis and colonization through osteoblastic CCL2 and RANKL activation

Bone Research, 2022
Bone metastases occur in patients with advanced-stage prostate cancer (PCa). The cell-cell interaction between PCa and the bone microenvironment forms a vicious cycle that modulates the bone microenvironment, increases bone deformities, and drives tumor ...
Jawed A Siddiqui, P. Seshacharyulu, Sakthivel Muniyan, R. Pothuraju, Parvez Khan, Raghupathy Vengoji, S. Chaudhary, S. K. Maurya, S. Lele, Maneesh Jain, K. Datta, M. Nasser, S. Batra   +12 more
semanticscholar   +1 more source

Ten-year retrospect of the investigation of proximal limbs metastasis in cancer: a multi-center study on survival outcome, limb function status and surgical procedures analysis

BMC Cancer, 2023
Background The aim of study was to evaluate survival outcome and limb function in cancer patients with proximal limbs metastasis. Associated factors on survival outcome and limb function were identified.
Chao Zhang, Jun Wang, Haixiao Wu, Yile Lin, Vladimir P. Chekhonin, Karl Peltzer, Artem V. Bukharov, Andrey D. Kaprin, Xu Guo, Zheng Liu   +9 more
doaj   +1 more source

The RANK/RANKL/OPG system and tumor bone metastasis: Potential mechanisms and therapeutic strategies

Frontiers in Endocrinology, 2022
With the markedly increased diagnosis and incidence of cancer in the population, tumor bone metastasis has become a frequent event in tumor patients. Healthy bone integrity is maintained by a delicate balance between bone formation and bone resorption ...
Yan Zhang, Jing-Qi Liang, Pei-Long Liu, Qiong Wang, L. Liu, Hongmou Zhao   +5 more
semanticscholar   +1 more source

Roles of the RANKL–RANK Axis in Immunity—Implications for Pathogenesis and Treatment of Bone Metastasis

Frontiers in Immunology, 2022
A substantial amount patients with cancer will develop bone metastases, with 70% of metastatic prostate and breast cancer patients harboring bone metastasis.
Bo Li, Pengru Wang, Jian Jiao, Haifeng Wei, Wei Xu, Pingting Zhou   +5 more
semanticscholar   +1 more source

Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer

Nature Communications, 2021
Bone metastasis is an incurable complication of breast cancer. In advanced stages, patients with estrogen-positive tumors experience a significantly higher incidence of bone metastasis (>87%) compared to estrogen-negative patients (
Kerui Wu, Jia-Hua Feng, Feng Lyu, F. Xing, Sambad Sharma, Yin Liu, Shih-Ying Wu, Dan Zhao, A. Tyagi, R. Deshpande, X. Pei, Marco Gabril Ruiz, Hiroyuki Takahashi, Shunsuke Tsuzuki, T. Kimura, Y. Mo, Y. Shiozawa, Ravi Singh, K. Watabe   +18 more
semanticscholar   +1 more source

m6A modification of lncRNA PCAT6 promotes bone metastasis in prostate cancer through IGF2BP2‐mediated IGF1R mRNA stabilization

Clinical and Translational Medicine, 2021
Background Bone metastasis is the leading cause of tumor‐related death in prostate cancer (PCa) patients. Long noncoding RNAs (lncRNAs) have been well documented to be involved in the progression of multiple cancers.
Chuandong Lang, C. Yin, Kaiyuan Lin, Yue Li, Qing Yang, Zhengquan Wu, Hong Du, Dong Ren, Yuhu Dai, Xinsheng Peng   +9 more
semanticscholar   +1 more source