Results 31 to 40 of about 381,513 (352)
Lung India, 2013 Background: To quantify the impact of bone metastasis and skeletal-related events (SREs) on mortality among older patients with lung cancer. Materials and Methods: Using the linked Surveillance, Epidemiology and End Results-Medicare database, we ...
Nalini Sathiakumar +8 more
doaj +1 more source
Role of SPARC in Bone Remodeling and Cancer‐Related Bone Metastasis [PDF]
, 2013 There is a growing socioeconomic recognition that clinical bone diseases such as bone infections, bone tumors and osteoporotic bone loss mainly associated with ageing, are major issues in today0s society.
Brekken, Rolf A. +3 more
core +1 more source
Chinese Journal of Lung Cancer, 2013 Background and objective Bone metastasis is common in lung cancer patients. The β isomer of the C-terminal telopeptide of type I collagen (β-CTX) and bone-specific alkaline phosphates (BAP) are regarded as important bone turnover markers in bone ...
Qiong TANG +3 more
doaj +1 more source
Mouse models for studying prostate cancer bone metastasis. [PDF]
, 2016 Once tumor cells metastasize to the bone, the prognosis for prostate cancer patients is generally very poor. The mechanisms involved in bone metastasis, however, remain elusive, because of lack of relevant animal models.
Dai, J. +4 more
core +1 more source
Trends in Bone Metastasis Modeling [PDF]
Cancers, 2020 Bone is one of the most common sites for cancer metastasis. Bone tissue is composed by different kinds of cells that coexist in a coordinated balance. Due to the complexity of bone, it is impossible to capture the intricate interactions between cells under either physiological or pathological conditions.
Laranga R. +5 more
openaire +4 more sources
NKX2-8/PTHrP Axis-Mediated Osteoclastogenesis and Bone Metastasis in Breast Cancer
Frontiers in Oncology, 2022 Bone metastasis is one of the most common distant metastasis of breast cancer, which could cause serious skeletal disease and increased cancer-related death.
Ainiwaerjiang Abudourousuli +15 more
doaj +1 more source
Osteocyte-Driven Downregulation of Snail Restrains Effects of Drd2 Inhibitors on Mammary Tumor Cells [PDF]
, 2018 While bone is a frequent target of breast cancer-associated metastasis, little is known about the effects of tumor-bone interactions on the efficacy of tumor-suppressing agents.
Chen, Andy +8 more
core +1 more source
Zhongliu Fangzhi Yanjiu, 2019 Objective To investigate the relationship between tumor markers of lung cancer and bone metastasis of whole body bone imaging in lung adenocarcinoma. Methods The whole body bone imaging of 278 patients diagnosed as lung adenocarcinoma in our hospital was
CAO Zhongnian +5 more
doaj +1 more source
Hallmarks of Bone Metastasis [PDF]
Calcified Tissue International, 2017 Breast cancer bone metastasis develops as the result of a series of complex interactions between tumor cells, bone marrow cells, and resident bone cells. The net effect of these interactions are the disruption of normal bone homeostasis, often with significantly increased osteoclast and osteoblast activity, which has provided a rational target for ...
Rachelle W. Johnson, Larry J. Suva
openaire +2 more sources
Journal of Experimental & Clinical Cancer Research, 2019 Background Clinically, prostate cancer (PCa) exhibits a high avidity to metastasize to bone. Myc-associated zinc-finger protein (MAZ) is a well-documented oncogene involved in the progression and metastasis of multiple cancer types, even in PCa. However,
Qing Yang +9 more
doaj +1 more source