Results 11 to 20 of about 76,730 (157)

Bone Morphogenetic Proteins [PDF]

Cold Spring Harbor Perspectives in Biology, 2016
Bone morphogenetic proteins (BMPs), originally identified as osteoinductive components in extracts derived from bone, are now known to play important roles in a wide array of processes during formation and maintenance of various organs including bone, cartilage, muscle, kidney, and blood vessels. BMPs and the related "growth and differentiation factors"
Takenobu, Katagiri, Tetsuro, Watabe
openaire   +2 more sources

Bone morphogenetic protein-2 influence on metabolic activity and proteoglycan synthesis by intervertebral disc cells

Acta Biomedica Scientifica, 2016
Modern therapeutic strategies for intervertebral disc repair mainly focus on targeting molecular pathways of extracellular matrix degeneration. Anabolic strategies for regeneration are aimed to increase production of major extracellular molecules ...
L. A. Bardonova, E. G. Belykh, V. A. Byvaltsev   +2 more
doaj   +1 more source

Effects of bioactive glass S53P4 or beta-tricalcium phosphate and bone morphogenetic protein-2 and bone morphogenetic protein-7 on osteogenic differentiation of human adipose stem cells

Journal of Tissue Engineering, 2012
The effects of bioactive glass S53P4 or beta-tricalcium phosphate; and bone morphogenetic proteins bone morphogenetic protein-2, bone morphogenetic protein-7, or bone morphogenetic protein-2 + 7 on osteogenic differentiation of human adipose stem cells ...
Martin Waselau, Mimmi Patrikoski, Miia Juntunen, Kasperi Kujala, Minna Kääriäinen, Hannu Kuokkanen, George K Sándor, Outi Vapaavuori, Riitta Suuronen, Bettina Mannerström, Brigitte von Rechenberg, Susanna Miettinen   +11 more
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Preliminary evaluation of BMP-2-derived peptide in repairing a peri-implant critical size defect: A canine model

Journal of the Formosan Medical Association, 2021
Background/Purpose: A synthetic bone morphogenetic protein (BMP)-2-derived peptide has been discovered to promote bone regeneration. The present study investigated the potential of the BMP-2 peptide combined with hydroxyapatite (HAp)/β-tricalcium ...
Yueh-Ling Chao, Li-Deh Lin, Hao-Hueng Chang, Tong-Mei Wang   +3 more
doaj   +1 more source

Addition of bone morphogenetic protein type 2 to ascorbate and β-glycerophosphate supplementation did not enhance osteogenic differentiation of human adipose-derived stem cells

Journal of Applied Oral Science, 2012
Bone morphogenetic protein type 2 (BMP-2) is a potent local factor, which promotes bone formation and has been used as an osteogenic supplement for mesenchymal stem cells.
Ariadne Cristiane Cabral Cruz, Mariana Lúcia Silva, Thiago Caon, Cláudia Maria Oliveira Simões   +3 more
doaj   +1 more source

Multiple roles of ALK3 in osteoarthritis: a narrative review

Bone & Joint Research, 2023
Osteoarthritis (OA) is a chronic degenerative joint disease characterized by progressive cartilage degradation, synovial membrane inflammation, osteophyte formation, and subchondral bone sclerosis.
Xianchun Ruan, Jinning Gu, Mingyang Chen, Fulin Zhao, Munire Aili, Demao Zhang   +5 more
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Cellular Response to Bone Morphogenetic Proteins-2 and -7 Covalently Bound to Photocrosslinked Heparin–Diazoresin Multilayer

Biomolecules, 2023
Despite the plethora of research that exists on recombinant human bone morphogenetic protein-2 and -7 (rhBMP-2 and rhBMP-7) and has been clinically approved, there is still a need to gain information that would allow for their more rational use in bone ...
Magdalena Wytrwal, Małgorzata Sekuła-Stryjewska, Agata Pomorska, Ewa Oclon, Ewa Zuba-Surma, Szczepan Zapotoczny, Krzysztof Szczubiałka   +6 more
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EXPERIMENTAL ESTIMATION OF COMPOSITE MATERIAL CONTAINING THE PROTEIN-MINERAL COMPONENTS AND RECOMBINANT BONE MORPHOGENETIC PROTEIN-2 AS A COVERING OF TITANIUM IMPLANTS

Travmatologiâ i Ortopediâ Rossii, 2011
The influence of both, the composite material based on the protein-mineral components including the prolonged form of the recombinant human bone morphogenetic protein 2 (rhBMP-2) and the method of the titanium implant’s surface treatment, on the ...
M. Z. Fedorova, S. V. Nadezhdin, A. S. Semikhin, M. A. Lazebnaya, G. V. Khramov, Y. R. Kolobov, A. V. Gromov, M. S. Bartov, V. G. Lunin, A. S. Karyagina, D. V. Gunderov   +10 more
doaj   +1 more source

Bone morphogenetic proteins: Periodontal regeneration

North American Journal of Medical Sciences, 2013
Periodontitis is an infectious inflammatory disease that results in attachment loss and bone loss. Regeneration of the periodontal tissues entails de novo formation of cementum, periodontal ligament, and alveolar bone. Several different approaches are currently being explored to achieve complete, reliable, and reproducible regeneration of periodontal ...
Rao, Subramaniam M, Ugale, Gauri M, Warad, Shivaraj B   +2 more
openaire   +3 more sources

Bone Morphogenetic Protein Coating on Titanium Implant Surface: a Systematic Review

eJournal of Oral Maxillofacial Research, 2017
Objectives: The purpose of the study is to systematically review the osseointegration process improvement by bone morphogenetic protein coating on titanium implant surface.
Haim Haimov, Natali Yosupov, Ginnady Pinchasov, Gintaras Juodzbalys   +3 more
doaj   +1 more source