Results 211 to 220 of about 78,836 (261)
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Growth Factors, 2003
Bone morphogenetic proteins (BMPs) are multi-functional growth factors that belong to the transforming growth factor beta (TGFbeta) superfamily. The roles of BMPs in embryonic development and cellular functions in postnatal and adult animals have been extensively studied in recent years. Signal transduction studies have revealed that Smad1, 5 and 8 are
Di, Chen, Ming, Zhao, Gregory R, Mundy
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Bone morphogenetic proteins (BMPs) are multi-functional growth factors that belong to the transforming growth factor beta (TGFbeta) superfamily. The roles of BMPs in embryonic development and cellular functions in postnatal and adult animals have been extensively studied in recent years. Signal transduction studies have revealed that Smad1, 5 and 8 are
Di, Chen, Ming, Zhao, Gregory R, Mundy
+8 more sources
Genes and Function, 1997
The concept that there is a substance in bone that can induce new-bone formation has been discussed for many years. However, the credit for the discovery of bone morphogenetic protein goes to Marshall R. Urist, who, in 1965, demonstrated the formation of bone by a process that he called autoinduction.
N, Ueno, M, Moos
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The concept that there is a substance in bone that can induce new-bone formation has been discussed for many years. However, the credit for the discovery of bone morphogenetic protein goes to Marshall R. Urist, who, in 1965, demonstrated the formation of bone by a process that he called autoinduction.
N, Ueno, M, Moos
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Biochemical and Biophysical Research Communications, 2007
Bone morphogenetic proteins (BMPs) are multi-functional growth factors belonging to the transforming growth factor-beta superfamily. It has been demonstrated that BMPs had been involved in the regulation of cell proliferation, survival, differentiation and apoptosis.
Yong-Tao, Xiao +2 more
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Bone morphogenetic proteins (BMPs) are multi-functional growth factors belonging to the transforming growth factor-beta superfamily. It has been demonstrated that BMPs had been involved in the regulation of cell proliferation, survival, differentiation and apoptosis.
Yong-Tao, Xiao +2 more
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Journal of neurosurgery. Spine, 2009
Although the authors used the same interbody spacers and even higher dose of rhBMP-2 (than the dose of rhBMP-2 was used in another report in which incidence of the resorptions after interbody fusions assisted with rhBMP-2 was 100%) there was no resorptions in their study. We asked for the authors' clarification of the strange phenomenon.
Smoljanović, Tomislav +2 more
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Although the authors used the same interbody spacers and even higher dose of rhBMP-2 (than the dose of rhBMP-2 was used in another report in which incidence of the resorptions after interbody fusions assisted with rhBMP-2 was 100%) there was no resorptions in their study. We asked for the authors' clarification of the strange phenomenon.
Smoljanović, Tomislav +2 more
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Journal of Dental Research, 1971
Bone morphogenetic protein (BMP) made by the process comprising the steps of demineralizing bone tissue; treating the demineralized bone tissue under aqueous conditions with a water soluble neutral salt and a solubilizing agent for the BMP, the agent being selected from the group consisting of urea and guanidine, and thereby transforming the bone ...
M R, Urist, B S, Strates
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Bone morphogenetic protein (BMP) made by the process comprising the steps of demineralizing bone tissue; treating the demineralized bone tissue under aqueous conditions with a water soluble neutral salt and a solubilizing agent for the BMP, the agent being selected from the group consisting of urea and guanidine, and thereby transforming the bone ...
M R, Urist, B S, Strates
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Bone morphogenetic proteins in bone tumors
Journal of Orthopaedic Science, 2004Bone morphogenetic proteins (BMPs), inducers of ectopic bone formation in vivo, are present in a number of osteosarcomas. BMPs are responsible for reactive bone formation, including periosteal reactions by normal osteoblasts, rather than production of tumorous osteoid by tumor cells.
Hideki, Yoshikawa +3 more
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Bone Morphogenetic Protein and Bone Morphogenetic Protein Gene Family in Bone Formation and Repair
Clinical Orthopaedics and Related Research, 1998The bone morphogenetic proteins are secreted signalling molecules that belong to the transforming growth factor beta family of growth and differentiation factors. Individual bone morphogenetic proteins are prominent at many sites during embryogenesis and are likely to be key regulators of early development and organogenesis.
J M, Wozney, V, Rosen
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Bone Morphogenetic Protein and Fusion
Journal of Neurosurgery: Spine, 2007In their article (Villavicencio AT, Burneikiene S, Nelson EL, et al: Safety of transforaminal lumbar interbody fusion and intervertebral recombinant human bone morphogenetic protein– 2. J Neurosurg Spine 3: 436– 443, December, 2005), Villavicencio and colleagues referred to the work by Haid et al., claiming that the fusion rates during ...
Pećina, Marko +2 more
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Bone morphogenetic proteins and their antagonists
Reviews in Endocrine and Metabolic Disorders, 2006Skeletal homeostasis is determined by systemic hormones and local factors. Bone morphogenetic proteins (BMPs) are unique because they induce the commitment of mesenchymal cells toward cells of the osteoblastic lineage and also enhance the differentiated function of the osteoblast.
Elisabetta, Gazzerro, Ernesto, Canalis
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Bone morphogenetic protein: a review
International Orthopaedics, 1991The osteogenic potential of bone and bone matrix has been characterised only by its biological effects and the parameters influencing it. Recently, the osteoinductive ability of bone matrix had been defined chemically by the description of a bone morphogenetic protein (BMP), and the parameters of osteogenic factors from different species have now been ...
G, Aldinger +5 more
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