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Progress in Growth Factor Research, 1989
Bone Morphogenetic Protein (BMP) refers to an activity derived from bone that induces the formation of cartilage and bone in vivo. This activity leads to a series of developmental processes including chemotaxis, proliferation, and differentiation, which result in the transient formation of cartilage and the production of living bone tissue, complete ...
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Bone Morphogenetic Protein (BMP) refers to an activity derived from bone that induces the formation of cartilage and bone in vivo. This activity leads to a series of developmental processes including chemotaxis, proliferation, and differentiation, which result in the transient formation of cartilage and the production of living bone tissue, complete ...
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The Bone Morphogenetic Proteins and Their Antagonists
2015The bone morphogenetic proteins (BMPs) and the growth and differentiation factors comprise a single family of some 20 homologous, dimeric cytokines which share the cystine-knot domain typical of the TGF-β superfamily. They control the differentiation and activity of a range of cell types, including many outside bone and cartilage.
Barbara, Mulloy, Chris C, Rider
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Bone Morphogenetic Proteins in Inflammation
2014Bone morphogenetic proteins (BMPs) are members of the transforming growth factor β (TGFβ) superfamily and control multiple organogenetic processes, cell proliferation and differentiation, apoptosis, and patterning of multiple organs from all three developmental envelopes including the skeleton, kidney, heart, pancreas, and eye. BMPs also have a role in
Grgurević, Lovorka +1 more
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Bone Morphogenetic Proteins and Bone Defects
Spine, 2007A systematic review of scientific literature.The study aimed to determine whether bone morphogenetic proteins (BMPs) are more effective in treating bone defects than traditional techniques, such as grafting autologous bone.BMPs were used in several human randomized controlled trials (RCTs).
MUSSANO F +4 more
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Immunogenicity of bone morphogenetic proteins
Journal of Neurosurgery: Spine, 2009Object The object of this paper is to review the immunogenicity of bone morphogenetic proteins (BMPs) and to compare the results of the immunogenicity characterization and clinical consequences between recombinant human (rh)BMP-2 and recombinant human osteogenic protein-1 (rhOP-1/BMP-7).
Hwang, C.J. +6 more
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Bone morphogenetic proteins in development
Current Opinion in Genetics & Development, 1996The bone morphogenetic proteins (BMPs) constitute a large family of cytokines related to members of the transforming growth factor-beta superfamily. Recent evidence, in particular from gene targeting experiments in the mouse, indicates that BMPs are required for mesoderm formation and for the development and patterning of many different organ systems ...
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Bone Morphogenetic Proteins (BMPs) and Bone Regeneration
2018Many research methods exist to elucidate the role of BMP-2 during bone regeneration. This chapter briefly reviews important animal models used in these studies and provides details on the rat femur defect model. This animal model is frequently utilized to measure the efficacy of osteogenic factors like BMP-2. Detailed information about delivery methods,
Deboleena, Kanjilal +1 more
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Effect of Bone Morphogenetic Protein-2 in the Treatment of Long Bone Non-Unions
Journal of Clinical Medicine, 2021Susanne Amler +2 more
exaly