Results 251 to 260 of about 27,645,133 (294)

Bone Morphogenetic Protein-2 Is a Regulator of Cell Adhesion

Experimental Cell Research, 1997
Bone morphogenetic proteins (BMPs) are a group of peptide growth factors closely related to transforming growth factors-beta. The BMPs are suggested to play an essential role in bone development and they are strong candidate molecules to be used clinically to improve fracture healing.
L, Nissinen, L, Pirilä, J, Heino
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A review on carrier systems for bone morphogenetic protein‐2

Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2016
ABSTRACTBone morphogenetic protein‐2 (BMP‐2) has unique bone regeneration property. The powerful osteoinductive nature makes it considered as second line of therapy in nonunion bone defect. A large number of carriers and delivery systems made up of different materials have been investigated for controlled and sustained release of BMP‐2.
Vishal, Agrawal, Mukty, Sinha
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Bone Morphogenetic Protein 2 Therapy for Craniofacial Surgery

Journal of Craniofacial Surgery, 2008
Between 2 and 10 years of age, the developing craniofacial skeleton poses a significant reconstructive challenge. Local autogenous bone is largely unavailable, distant bone grafts are fraught with significant morbidity and limited yield, and alloplastic materials are incompatible with the growing calvarium and facial skeleton.
Darren M, Smith, Gregory M, Cooper, Mark P, Mooney, Kacey G, Marra, Joseph E, Losee   +4 more
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Potential of Recombinant Human Bone Morphogenetic Protein-2 in Bone Regeneration

Implant Dentistry, 1999
Recombinant human bone morphogenetic protein (rhBMP-2) has been used as a bone substitute. This article describes the rhBMP-2 structure, mechanisms of action, carriers, advantages, safety, and recent clinical studies relevant to dentistry.
E, Barboza, A, Caúla, F, Machado
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Expression of bone morphogenetic protein-6 and -2 and a bone morphogenetic protein antagonist in horses with naturally acquired osteochondrosis

American Journal of Veterinary Research, 2004
Abstract Objective —To determine the mRNA expression of bone morphogenetic protein (BMP)-6 and -2 and a BMP antagonist (Noggin) in horses with osteochondrosis. Sample Population —Samples of articular cartilage from ...
Stacy A, Semevolos, Alan J, Nixon, M Lisa, Strassheim   +2 more
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Bone morphogenetic protein‐2 for peri‐implant bone regeneration and osseointegration

Clinical Oral Implants Research, 1997
Recombinant human bone morphogenetic protein‐2 (rhBMP‐2) induced bone regeneration and osseointegration was evaluated in supra‐alveolar peri‐implant defects in 5 beagle dogs. Alveolar bone was reduced 5 mm in height in mandibular premolar areas and the premolars were extracted.
T J, Sigurdsson, E, Fu, D N, Tatakis, M D, Rohrer, U M, Wikesjö   +4 more
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Repair of Bone Allograft Fracture Using Bone Morphogenetic Protein-2

Clinical Orthopaedics and Related Research, 2002
Long-term clinical data have shown that reconstruction using bone allografts provide adequate function after extensive tumor surgery. Complications such as nonunion of allograft-host interface, infection, and allograft fracture often require major revision surgeries.
Francis Young-In, Lee, Stephen, Storer, Eric J, Hazan, Mark C, Gebhardt, Henry J, Mankin   +4 more
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Mechanisms of Bone Morphogenetic Protein 2 in Respiratory Diseases

Current Allergy and Asthma Reports
Bone morphogenetic protein 2 (BMP2) belongs to the transforming growth factor-β (TGF-β) superfamily and plays an important role in regulating embryonic development, angiogenesis, osteogenic differentiation, tissue homeostasis, and cancer invasion. Increasing studies suggest BMP2 is involved in several respiratory diseases.
Yiqiong Wen, Yuanyuan Zheng, Shu Hua, Tongfen Li, Xiaoqing Bi, Qiongfen Lu, Min Li, Shibo Sun   +7 more
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Bone Formation with Use of rhBMP-2 (Recombinant Human Bone Morphogenetic Protein-2)*

The Journal of Bone & Joint Surgery, 1997
We examined the effect of rhBMP-2 (recombinant human bone morphogenetic protein-2), delivered in a porous poly(DL-lactic acid) implant, on bone formation in a critical-sized defect in the radial diaphysis in rabbits. A unilateral segmental defect, twenty millimeters long, was created in the radius in ninety-six skeletally mature New Zealand White ...
H D, Zegzula, D C, Buck, J, Brekke, J M, Wozney, J O, Hollinger   +4 more
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Bone morphogenetic protein 2 (BMP-2) and induction of tumor angiogenesis

Journal of Cancer Research and Clinical Oncology, 2005
Bone morphogenetic proteins (BMPs) are members of the transforming growth factor-beta family and play an important role in the regulation of embryonic vasculogenesis but their role in postnatal angiogenesis remains to be clarified. In this study we investigated a possible role of BMP-2 in the promotion of tumor angiogenesis.We studied the effect of BMP-
Martin, Raida, Joachim H, Clement, Russell D, Leek, Kurosh, Ameri, Roy, Bicknell, Dietger, Niederwieser, Adrian L, Harris   +6 more
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