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Changes in bone morphogenetic protein receptor-IB localisation regulate osteogenic responses of human bone cells to bone morphogenetic protein-2

The International Journal of Biochemistry & Cell Biology, 2008
Cell responses to bone morphogenetic proteins (BMP) depend on the expression and surface localisation of transmembrane receptors BMPR-IA, -IB and -II. The present study shows that all three antigens are readily detected in human bone cells. However, only BMPR-II was found primarily at the plasma membrane, whereas BMPR-IA was expressed equally in the ...
Weerachai, Singhatanadgit   +3 more
openaire   +2 more sources

Application of alginate microbeads as a carrier of bone morphogenetic protein‐2 for bone regeneration

Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2018
AbstractBone morphogenetic protein‐2 (BMP‐2) is commonly used to enhance bone regeneration. The potential of BMP‐2 for bone regeneration varies according to the concentration and release kinetics on the implanted site. Therefore, it is important to determine appropriate carriers of BMP‐2. However, no optimal delivery vehicles have been identified.
Yun Hwan, Lee   +5 more
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Clinical Evaluation of Recombinant Human Bone Morphogenetic Protein-2

Clinical Orthopaedics and Related Research, 2002
Recombinant human bone morphogenetic protein-2 is an osteoinductive protein that plays a pivotal role in bone growth and regeneration. Several hundred studies were conducted in the past 7 years in numerous animal models to establish unequivocally the efficacy, safety, mechanism of action, pharmacokinetics, and surgical handling properties of ...
Alexandre, Valentin-Opran   +4 more
openaire   +2 more sources

Bone morphogenetic protein-2 in temporomandibular joints with internal derangement

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 1999
The purpose of this study was to analyze the expression of bone morphogenetic protein-2 (BMP-2) in patients with internal derangement of the temporomandibular joint.Twenty-one human temporomandibular joint samples (5 extirpated disks and 16 biopsy specimens of synovitis area from patients with internal derangement of the TMJ) and 2 control ...
T, Suzuki   +4 more
openaire   +2 more sources

Bone Augmentation Using Allogeneic Bone Blocks With Recombinant Bone Morphogenetic Protein-2

Implant Dentistry, 2017
Because of limitations of the absorbable collagen sponge (ACS), recombinant bone morphogenetic protein (rhBMP-2) requires a scaffolding device for ridge augmentation.Twenty-one patients were treated with 37 allogeneic block grafts and rhBMP-2/ACS.
openaire   +2 more sources

Adverse events and bone morphogenetic protein-2

The Spine Journal, 2011
Elizabeth A, Salisbury   +2 more
openaire   +2 more sources

Editorial: Recombinant human bone morphogenetic protein–2

Journal of Neurosurgery: Spine, 2013
Shaffrey, Christopher I, Smith, Justin S
openaire   +2 more sources

Effects of bone morphogenetic protein 2 and 7 on bone metabolism

2014
Koštani morfogenetski proteini (BMP)2 i 7 nakon niza kliničkih studija odobreni su od strane FDA za liječenje kompliciranih fraktura tibije te za spinalnu fuziju. Nakon dobrih rezultata u odobrenim indikacijama opisano je njihovo korištenje i kod fraktura humerusa, skafoidne kosti te prijeloma čeljusti.
Vukičević, Slobodan   +3 more
openaire  

Bone morphogenetic protein-2

Reactions Weekly, 2016
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