Results 131 to 140 of about 88,042,096 (284)

Calcium citrate: a new biomaterial that can enhance bone formation in situ

Chinese Journal of Traumatology, 2012
【Abstract】 Objective: To investigate the effect of a new biomaterial combining calcium citrate and recombinant human bone morphogenetic protein-2 (rhBMP-2) on bone regeneration in a bone defect rabbit model. Methods: Totally 30 male New Zealand
WANG Li-ming, WANG Wei, LI Xiu-cui, PENG Lei, LIN Zhong-qin, XV Hua-zi   +5 more
doaj  

Modulation of bone morphogenetic protein-2 and bone morphogenetic protein-4 gene expression in osteoblastic cell lines.

Cellular and molecular biology (Noisy-le-Grand, France), 1999
Bone morphogenetic proteins (BMPs) belong to the transforming growth factor-beta (TGF-beta) superfamily and are crucial factors in the process of bone formation. Despite knowledge on their wide distribution and expression, however, there is very little information on the biological factors that affect gene transcription of these osteoinductive agents ...
Virdi, A., Cook, L., Oreffo, R., Triffitt, J.   +3 more
openaire   +2 more sources

Membrane lipid metabolism as a regulatory frontier in neural crest biology: Roles for sphingolipids, cholesterol, and lipid rafts

Developmental Dynamics, EarlyView.
Abstract Neural crest cells are multipotent, migratory stem‐like cells essential for vertebrate development that contribute broadly to many tissues including the craniofacial skeleton, peripheral nervous system, and pigment‐producing cells. Their development progresses through phases of induction, specification, delamination, migration, and ...
Allison E. Mancini, Mallorie P. Jenne, Michael L. Piacentino   +2 more
wiley   +1 more source

Role of Bone Morphogenetic Protein 4 in the Inflammation of the Myocardium and Vascular Tissue of Obese Mice. [PDF]

J Cardiovasc Pharmacol, 2022
Wu T, Chen L, Shen Q, Wang L, Zong GJ.
europepmc   +1 more source

The Mouse Bone Morphogenetic Protein-4 Gene [PDF]

Journal of Biological Chemistry, 1995
Jian Q. Feng, Di Chen, Austin J. Cooney, Ming-Jer Tsai, Marie A. Harris, Sophia Y. Tsai, Mei Feng, Gregory R. Mundy, Stephen E. Harris   +8 more
openaire   +1 more source

Bone induction in monkeys by bone morphogenetic protein. A trans-filter technique

, 1993
We investigated bone induction by bone morphogenetic protein in primates, comparing it with that seen in rodents. Twelve Millipore diffusion chambers containing 5 mg of semipurified bone morphogenetic protein were implanted into the dorsal muscles of 12
S Miyamoto, K Takaoka, K Ono
core   +1 more source

Increased calcification by erythrophagocytosis in aortic valvular interstitial cells

ESC Heart Failure, Volume 12, Issue 2, Page 1469-1473, April 2025.
Abstract Background Calcific aortic valve disease (CAVD) progresses over time to severe aortic stenosis and eventually heart failure. Recent evidence indicates that intraleaflet haemorrhage (ILH) strongly promotes CAVD progression. However, it remains poorly understood how it mechanistically contributes to valvular calcification.
Zihan Qin, Magnus Bäck, Anders Franco‐Cereceda, Sven‐Christian Pawelzik   +3 more
wiley   +1 more source

Melatonin mediates the BMP4/MAPK signaling pathway to alleviate zearalenone-induced abnormal embryonic development in mice

Ecotoxicology and Environmental Safety
Zearalenone (ZEA) is a common mycotoxin found in crops that poses a threat to human health, particularly the female reproductive system. Here, we show that exposing mouse zygotes to ZEA in vitro significantly impairs embryo development, leading to embryo
Mengyao Wang, Zhixin Pu, Jing Zhang, Peiwen Wang, Yaxin Chen, Yating Zhu, Hongzhen Ruan, Dongmei Ji, Weiwei Zou, Huiru Cheng, Zhiming Ding, Yunxia Cao, Yajing Liu, Dan Liang   +13 more
doaj   +1 more source

The osteogenesis of bacterial cellulose scaffold loaded with bone morphogenetic protein-2.

, 2012
Bacterial cellulose (BC) is a nanofibrous biological material with attractive physicochemical properties and biocompatibility. Its fiber is similar to the collagenous fiber of bone.
Lei Chen, Yang Li, Hua Zhang, Zhaoxu Wang*, Qin Shi(施勤), Jie Sun(孙杰), Bing Chen, Huilin Yang   +7 more
core  

Methotrexate inhibits BMP4 and abrogates the hypertrophic chondrocyte phenotype of synovial fibroblasts in juvenile idiopathic arthritis

Pediatric Rheumatology Online Journal
Background Juvenile Idiopathic Arthritis (JIA) induces growth disturbances in affected joints. Fibroblast-like synoviocytes (FLS) play a crucial role in JIA pathogenesis.
Megan M. Simonds, Samuel T. Freer, Anne Marie C. Brescia   +2 more
doaj   +1 more source