Results 141 to 150 of about 183,822 (327)

Atomically precise metal cluster enzymes for pathological tissue regeneration

BMEMat, EarlyView.
Schematic illustration of atomically precise metal cluster enzymes (MCEs) for pathological tissue regeneration. Atomically precise MCEs can modulate biological processes, such as attenuation of inflammatory responses, eradication of bacterial pathogens, regulation of angiogenesis, and promotion of cell development.
Ziqiang Xiong, Zhifeng Shi, Mengqing Li, Jien Han, Haoyan Chen, Maofei Ran, Shaojian Zhong, Limin Ma, Chengyun Ning, Youzhun Fan, Zhenghua Tang, Peng Yu   +11 more
wiley   +1 more source

Association of plasma bone morphogenetic protein-4 levels with arterial stiffness in hypertensive patients. [PDF]

J Clin Lab Anal, 2022
Wang N, Guo Y, Dong Y, Li X, Liu Q, Liu Q, Wang G, Qin M, Zhang Z, Song J, Liang L, Zhong J.   +11 more
europepmc   +1 more source

Role for TGF-beta superfamily signaling in telencephalic GABAergic neuron development. [PDF]

, 2010
Signaling mechanisms mediated by the Transforming Growth Factor-beta (TGF-beta) superfamily regulate a variety of developmental processes. Here we show that components of both bone morphogenetic protein/growth differentiation factor and TGF-beta/activin ...
Lee, Amie Y, Long, Jason E, Maira, Mario, Rubenstein, John LR, Stifani, Stefano   +4 more
core  

Engineering Lipid Nanoparticles for Precision RNA Delivery: Design Principles, Targeting Strategies, and Clinical Prospects

Cancer Nexus, EarlyView.
ABSTRACT Lipid nanoparticles (LNPs) represent the most clinically advanced platform for RNA delivery and have enabled major breakthroughs in vaccines and gene therapies. However, their broader application is still limited by inefficient extrahepatic delivery, immunogenicity, and insufficient control over tissue‐ and cell‐specific targeting. This review
Yu Han, Ying Wang, Xintao Gao, Yan Lei, Yantao Li, Zhiyong Tang   +5 more
wiley   +1 more source

Robinow syndrome DVL1 variants disrupt morphogenesis and appendage formation in a Drosophila disease model

Developmental Dynamics, EarlyView.
Abstract Background Robinow syndrome is a rare developmental syndrome caused by variants in genes in Wnt signaling pathways. We previously showed that expression of patient variants in Dishevelled 1 (DVL1) in Drosophila and chicken models disrupts the balance of canonical and non‐canonical Wnt signaling.
Gamze Akarsu, Katja R. MacCharles, Kenneth Kin Lam Wong, Joy M. Richman, Esther M. Verheyen   +4 more
wiley   +1 more source

Calcium citrate: a new biomaterial that can enhance bone formation in situ

Chinese Journal of Traumatology, 2012
【Abstract】 Objective: To investigate the effect of a new biomaterial combining calcium citrate and recombinant human bone morphogenetic protein-2 (rhBMP-2) on bone regeneration in a bone defect rabbit model. Methods: Totally 30 male New Zealand
WANG Li-ming, WANG Wei, LI Xiu-cui, PENG Lei, LIN Zhong-qin, XV Hua-zi   +5 more
doaj  

The Mouse Bone Morphogenetic Protein-4 Gene [PDF]

Journal of Biological Chemistry, 1995
Jian Q. Feng, Di Chen, Austin J. Cooney, Ming-Jer Tsai, Marie A. Harris, Sophia Y. Tsai, Mei Feng, Gregory R. Mundy, Stephen E. Harris   +8 more
openaire   +1 more source

Identification of novel genes regulating the development of the palate

Developmental Dynamics, EarlyView.
Abstract Background The International Mouse Phenotyping Consortium (IMPC) has generated thousands of knockout mouse lines, many of which exhibit embryonic or perinatal lethality. Using micro‐computed tomography (micro‐CT), the IMPC has created and publicly released three‐dimensional image data sets of embryos from these lethal and subviable lines.
Ashwin Bhaskar, Sophie Astrof
wiley   +1 more source

Bone morphogenetic protein 4 (BMP4) [PDF]

Science-Business eXchange, 2011
openaire   +3 more sources

Reconstruction of maxillofacial bone defects: Contemporary methods and future techniques [PDF]

, 2014
Reconstruction of maxillofacial continuity defects has always been a challenging tasks for the scientist and surgeons over the years. The main goal of the reconstruction of the maxillofacial region is to restore facial form, function, full ...
Alfotawi, R., Ayoub, A.
core